The catalytic mechanism of cytochrome P-450. Spin-trapping evidence for one-electron substrate oxidation (original) (raw)

Substrate mediated redox partner selectivity of cytochrome P450

Lucy Waskell

Chemical Communications, 2018

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Mechanistic Studies of 9-Ethynylphenanthrene-Inactivated Cytochrome P450 2B1

Ute Kent

Archives of Biochemistry and Biophysics, 1995

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Reaction profile of the last step in cytochrome P-450 catalysis revealed by studies of model complexes

Zeev Gross

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One small step for cytochrome P450 in its catalytic cycle, one giant leap for enzymology

Huriye Erdogan

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Water as biocatalyst in cytochrome P450

devesh kumar

Faraday Discussions, 2011

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Cytochrome P450 E1 (CYP2E1)

Richa Garva

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Searching for the Second Oxidant in the Catalytic Cycle of Cytochrome P450: A Theoretical Investigation of the Iron(III)-Hydroperoxo Species and Its Epoxidation Pathways

Pankaj Sharma

Journal of the American Chemical Society, 2002

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Resonance Raman Studies of Cytochrome P450 2B4 in Its Interactions with Substrates and Redox Partners

Lucy Waskell

Biochemistry, 2008

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New Features In the Catalytic Cycle of Cytochrome P450 During the Formation of Compound I From Compound 0

Jingjing Zheng

J. Phys. Chem. …, 2005

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Direct formation of complexes between cytochrome P-450 and nitrosoarenes

Arthur Cho

Biochemistry, 1986

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Formation of a Novel Reversible Cytochrome P450 Spectral Intermediate: Role of Threonine 303 in P450 2E1 Inactivation †

Ute Kent

Biochemistry, 2004

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Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes

Sason SHAIK

Chemical Reviews, 2004

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Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms

Christal Sohl

Archives of Biochemistry and Biophysics, 2011

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Oxygen Economy of Cytochrome P450: What Is the Origin of the Mixed Functionality as a Dehydrogenase−Oxidase Enzyme Compared with Its Normal Function?

devesh kumar

Journal of the American Chemical Society, 2004

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An Assessment of the Reaction Energetics for Cytochrome P450-Mediated Reactions

Sreedhara Voleti

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Assignment on Molecular Mechanism of Interaction of Cytochrome P-450

Nahid Mahamud

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Selective inactivation of cytochrome P-450 isozymes by suicide substrates

Bruce Mico

Archives of Biochemistry and Biophysics, 1981

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Models for the enzymatically active state of cytochrome p-450

Robert Kirchner

International Journal of Quantum Chemistry, 2009

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Cytochrome P-450 oxygen intermediates and reactivity at subzero temperatures

K Kristoffer Andersson

Journal of Molecular Catalysis, 1980

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Two-state reactivity mechanisms of hydroxylation and epoxidation by cytochrome P-450 revealed by theory

Sason SHAIK

Current Opinion in Chemical Biology, 2002

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Kinetics of Oxidation of Benzphetamine by Compounds I of Cytochrome P450 2B4 and Its Mutants

Lucy Waskell

Journal of the American Chemical Society, 2009

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Spectra and Kinetic Studies of the Compound I Derivative of Cytochrome P450 119

Xin Sheng

Journal of the American Chemical Society, 2008

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Specificity of the cytochrome P-450 interaction with cytochromeb5

Fred Friedman

FEBS Letters, 1994

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Cytochromes P450: a success story

Daniele Werck-reichhart

Genome Biol, 2000

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Unusual Cytochrome P450 Enzymes and Reactions

Andrew Tyler Munro

Journal of Biological Chemistry, 2013

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A model compound study of the CO-adduct of cytochrome P-450

jerry stern

The Journal of biological chemistry, 1974

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The cytochrome P450 1A2 active site: Topology and perturbations caused by glutamic acid-318 and threonine-319 mutations

Paul Ortiz de Montellano

Biochemistry, 1993

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Protein engineering of cytochromes P-450

Michael Noble

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000

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NADPH and H2O2-dependent reactions of cytochromeP-450LMcompared with peroxidase catalysis

Reinhard Renneberg

FEBS Letters, 1978

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The Catalytic Site of Cytochrome P4504A11 (CYP4A11) and Its L131F Mutant

Elizabeth Dierks

Journal of Biological Chemistry, 1998

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Direct observation of substrate binding to ferrous-CO cytochrome P-450-CAM using 19 F NMR

George Crull

FEBS Letters, 1989

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Formation of the Active Species of Cytochrome P450 by Using Iodosylbenzene: A Case for Spin‐Selective Reactivity

Yohann Moreau

… A European Journal, 2007

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Rabbit liver cytochrome P-450 2B5: high-level expression of the full-length protein in Escherichia coli, purification, and catalytic activity

Rita Bernhardt

Biochimica et Biophysica Acta (BBA) - General Subjects, 1995

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Quantitative Production of Compound I from a Cytochrome P450 Enzyme at Low Temperatures. Kinetics, Activation Parameters, and Kinetic Isotope Effects for Oxidation of Benzyl Alcohol

Xin Sheng

Journal of the American Chemical Society, 2009

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Ligand binding studies of engineered cytochrome P-450d wild type, proximal mutants, and distal mutants

Abu Sadeque

Biochemistry, 1991

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