Site-directed mutagenesis of Arginine282 suggests how protons and peptides are co-transported by rabbit PepT1 (original) (raw)

The mammalian proton-coupled peptide cotransporter PepT1: sitting on the transporter–channel fence?

David Meredith

Philosophical Transactions of the Royal Society B: Biological Sciences, 2009

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The transmembrane tyrosines Y56, Y91 and Y167 play important roles in determining the affinity and transport rate of the rabbit proton-coupled peptide transporter …

Myrtani Pieri

The International Journal of …, 2009

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Site-directed Mutation of Arginine 282 to Glutamate Uncouples the Movement of Peptides and Protons by the Rabbit Proton-peptide Cotransporter PepT1

David Meredith

Journal of Biological Chemistry, 2004

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The transmembrane tyrosines Y56, Y91 and Y167 play important roles in determining the affinity and transport rate of the rabbit proton-coupled peptide transporter PepT1

Myrtani Pieri

The International Journal of Biochemistry & Cell Biology, 2009

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From Bacteria to Man: Archaic Proton-Dependent Peptide Transporters at Work

B. Spanier

Physiology, 2006

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Structural insights into substrate recognition in proton-dependent oligopeptide transporters

Caroline Jegerschöld, Lionel Trésaugues

EMBO reports, 2013

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Modified amino acids and peptides as substrates for the intestinal peptide transporter PepT1

Richard Boyd

European Journal of Biochemistry, 2000

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Unified modeling of the mammalian and fish proton-dependent oligopeptide transporter PepT1

Elena Bossi

Channels (Austin, …, 2011

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Residues R282 and D341 act as electrostatic gates in the proton-dependent oligopeptide transporter PepT1

Antonio Peres

The Journal of Physiology, 2011

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Minimal Molecular Determinants of Substrates for Recognition by the Intestinal Peptide Transporter

Hannelore H Daniel

Journal of Biological Chemistry, 1998

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Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1

Michael Bolger

Journal of Pharmaceutical Sciences, 1998

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Current Perspectives on Established and Putative Mammalian Oligopeptide Transporters

Dea Herrera-Ruiz

Journal of pharmaceutical …, 2003

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Molecular Identification of a Role for Tyrosine 167 in the Function of the Human Intestinal Proton Coupled Dipeptide Transporter (hPepT1

chun chu

Biochemical and Biophysical Research Communications, 1998

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A cluster of proton/amino acid transporter genes in the human and mouse genomes☆

Martin Foltz

Genomics, 2003

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Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor

Jean-Marc Jeckelmann

Communications Chemistry, 2022

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Substrate specificity and transport mode of the proton-dependent amino acid transporter mPAT2

Martin Foltz

European Journal of Biochemistry, 2004

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Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport

David Meredith

Structure (London, England : 1993), 2015

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Substrate recognition by the mammalian proton-dependent amino acid transporter PAT1

Martin Foltz

Molecular Membrane Biology, 2003

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An update on renal peptide transporters

Hannelore H Daniel

American journal of physiology. Renal physiology, 2003

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Molecular cloning and tissue distribution of rat peptide transporter PEPT2

Ken-Ichi Inui

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1996

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Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions

Himansha Singh, Hendrik W . van Veen

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Defining Minimal Structural Features in Substrates of the H+/Peptide Cotransporter PEPT2 Using Novel Amino Acid and Dipeptide Derivatives

Hannelore H Daniel

Molecular Pharmacology, 2002

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The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters

Fritz Markwardt

FEBS Journal, 2010

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Faculty Opinions recommendation of Proton movement and coupling in the POT family of peptide transporters

Richard Naftalin

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2017

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Expression cloning of a cDNA from rabbit small intestine related to proton-coupled transport of peptides, ßlactam antibiotics and ACE-inhibitors

Heini Murer

Pflügers Archiv European Journal of Physiology, 1994

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The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics

Carsten Uhd Nielsen, Birger Brodin

British Journal of Pharmacology, 2010

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Functional Characterization of Two Novel Mammalian Electrogenic Proton-dependent Amino Acid Cotransporters

Hannelore H Daniel

Journal of Biological Chemistry, 2002

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Intestinal peptidases form functional complexes with the neutral amino acid transporter B 0 AT1

S. Bröer

Biochemical Journal, 2012

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Computational modelling of H+-coupled peptide transport via human PEPT1

Ken-Ichi Inui

The Journal of physiology, 2005

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