Assessment Of Lymph Node Tumour Mass From CT Scans : How Good Is Diameters And Visual Assessment (original) (raw)

Journal of Medical Physics, 1995

Abstract

The evaluation response of tumours requires quantification of tumour mass in terms of volume or maximum diameter. In normal practice changes in maximum diameter of tumour are assessed visually on follow-up CT films. This may lead to erroneous results. Twenty one patients of testicular cancer in stage I1 A to I1 D with retroperitoneal lymphadenopathy were scanned by CT for 3 to 5 times during the course of treatment. Tumour size was assessed in terms of diameter as per practice followed routinely. Avery important observation was that actual measurement of diameter instead of visual assessment resulted in change of stage of cancer in 42.8% (9 out of 21) cases. Moreover, in 6 out of these 21 cases (28%) there occurred a change in stage from I1 C to II D which assumes significance due to change in treatment protocol from BEP (Bleomycin. Etoposide, Cisplatinum) to BOP-VIP (Bleomycin, Vincristin, Cisplatinum, VP-16, Ifosfamide, Cisplatinum). Tumour volume estimated on the basis of visual ...

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