The binding site for allosteric modulators of AMPA receptor (original) (raw)
2004, Doklady Biochemistry and Biophysics
AI-generated Abstract
The paper investigates the binding site for allosteric modulators of AMPA receptors, focusing on compounds such as cyclothiazide and new analogues of piperonylic and benzodioxane-6 carboxylic acids. It highlights the importance of these modulators in neurophysiological processes and their potential therapeutic roles in treating neurodegenerative disorders. Through molecular docking studies, the paper identifies interactions within the binding pocket and suggests avenues for designing novel allosteric ligands.
Sign up for access to the world's latest research.
checkGet notified about relevant papers
checkSave papers to use in your research
checkJoin the discussion with peers
checkTrack your impact