EVALUATION OF THE LOCOMOTOR AND DIURETIC ACTIVITIES OF ETHANOLIC EXTRACT OF LEAVES OF CAPPARIS DIVARICATA LAM. (CAPPARIDACEAE) Research Article (original) (raw)

2011

Abstract

The aim of the present study was to evaluate the locomotor and diuretic activities of ethanolic extract of leaves of Capparis divaricata Lam. (EEC) in experimental animals. Locomotor activity was evaluated by actophotometer in mice and diuretic activity was evaluated using in-vivo Lipschitz test model in rats. Oral administration of EEC at doses 250 mg/kg and 500 mg/kg produced significant (P< 0.01) CNS depression by reducing locomotor activity while it showed a significant (P< 0.01) increase in the urine volume when compared to control. Thus, in conclusion the EEC has a significant CNS depression action by reducing locomotor in mice and diuretic action in rats. Preliminary phytochemical screening showed the presence of alkaloids, flavonoids, phenolic compounds, glycosides, tannins and saponins.

Manish Kondawar hasn't uploaded this paper.

Let Manish know you want this paper to be uploaded.

Ask for this paper to be uploaded.