P53 gene: major mutations in neoplasias and anticancer gene therapy (original) (raw)

p53: From Fundamental Biology to Clinical Applications in Cancer

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P53 HOW CRUCIAL IS ITS ROLE IN CANCER? DR. PHILOMENA GEORGE International Journal of Current Pharmaceutical Research Vol 3, Issue 2, 2011,ISSN- 0975-7066

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p53 at a Glance: The Story So Far…

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Twenty years of p53 research: structural and functional aspects of the p53 protein

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Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression

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P53 (protein 53 kDa)

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Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011

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P53 from Pathway to Therapy

David LANE

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Recent advances in p53 research: an interdisciplinary perspective

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P53 transcriptional activities: A general overview and some thoughts

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P53: Its Role in Carcinogenesis And Also A Novel Target for Anti-Cancer Therapy

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Mutant p53 proteins: Between loss and gain of function

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P53 HOW CRUCIAL IS ITS ROLE IN CANCER?

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p53 alterations in human cancer: more questions than answers

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Gene Regulation by p53 in Human Cancer System

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Sequence analysis of the tumour suppressor protein p53 and its implications

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Ory K, Legros Y, Auguin C, Soussi T.. Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation. EMBO J 13: 3496-3504

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Mutant p53: an oncogenic transcription factor

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Role of P53 Gene.pdf

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p53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53

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Restoration of wild-type p53 function in human cancer: Relevance for tumor therapy

Gianluca Bossi

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The first 30 years of p53: growing ever more complex

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P53 Family: At the Crossroads in Cancer Therapy

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[P53 tumor suppressor gene]

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p53: Twenty five years understanding the mechanism of genome protection

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The p53 Tumor Suppressor Gene: From Molecular Biology to Clinical Investigation

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More targets, more pathways and more clues for mutant p53

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Life and death by P53

Wen-hwa Lee

BioEssays, 1995

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Recent findings on the role of wild-type and mutant p53 in cancer development and therapy

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Role of p53 in Human Cancers

Yusuf TUTAR

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Tumour associated mutants of p53 can inhibit transcriptional activity of p53 without heterooligomerization

Toivo Maimets, Arnold Kristjuhan

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p53-based Cancer Therapy

Chit Fang Cheok

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