GABA receptors (original) (raw)

Characterization in Rats of the Anxiolytic Potential of ELB139 [1-(4-Chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a New Agonist at the Benzodiazepine Binding Site of the GABAA Receptor

Shahram Akbarzadeh

Journal of Pharmacology and Experimental Therapeutics, 2005

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Benzodiazepine Binding Site Occupancy by the Novel GABAA Receptor Subtype-Selective Drug 7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in Rats, Primates, and Humans

Bindi Sohal

Journal of Pharmacology and Experimental Therapeutics, 2009

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Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series

Frederic Knoflach

Bioorganic & Medicinal Chemistry Letters, 2009

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Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: The approximated activation of receptor subtypes may explain behavioral effects

Bojan Markovic

Brain Research, 2014

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Are GABAA Receptors Containing α5 Subunits Contributing to the Sedative Properties of Benzodiazepine Site Agonists?

Dubravko Bokonjic

Neuropsychopharmacology, 2008

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Benzodiazepine Binding Site Occupancy by the Novel GABAA Receptor Subtype-Selective Drug 7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in Rats, Primates, and Humans

sandra sanabria

Journal of Pharmacology and Experimental Therapeutics, 2010

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Interaction of SQ 20009 and GABA-like drugs as modulators of benzodiazepine receptor binding

Porntip Supavilai

European Journal of Pharmacology, 1980

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Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes

Uwe Rudolph

Nature Reviews Drug Discovery, 2011

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A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model

Michael Poe

International Journal of Medicinal Chemistry, 2015

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benzodiazepine receptor ligands a patent review (2006-2012).pdf

Gabriella Guerrini

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Benzodiazepine receptor ligands: a patent review (2006 – 2012)

Gabriella Guerrini

Expert Opinion on Therapeutic Patents, 2013

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Inhibition of γ-aminobutyric acid stimulated [3H]diazepam binding by benzodiazepine receptor ligands

Phil Skolnick

Biochemical Pharmacology, 1981

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Gaba Receptors and Benzodiazepines

Colin Goodchild

BJA: British Journal of Anaesthesia, 1993

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Modulation of benzodiazepine receptor binding: Insight into pharmacological efficacy

William Roeske

European Journal of Pharmacology, 1982

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Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation

Holger Rabe, Hartmut Lüddens

European Journal of Pharmacology, 2011

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Chronic treatment with diazepam or the inverse benzodiazepine receptor agonist FG 7142 causes differential changes in the effects of GABA receptor stimulation

Dai Stephens

Epilepsy Research, 1988

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Chronic exposure of cells expressing recombinant GABAA receptors to benzodiazepine antagonist flumazenil enhances the maximum number of benzodiazepine …

Dubravka Švob Štrac

Life sciences, 2004

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Biological function of GABAA/benzodiazepine receptor heterogeneity

Hartmut Lüddens

Journal of Psychiatric Research, 1995

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Computer-aided design of selective ligands of the benzodiazepine-binding site of the GABAA receptor

Vladimir Chupakhin

Doklady Chemistry, 2008

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Triazolam is more efficacious than diazepam in a broad spectrum of recombinant GABAA receptors

Stefano Vicini

European Journal of Pharmacology: Molecular Pharmacology, 1993

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Chronic exposure of cells expressing recombinant GABAA receptors to benzodiazepine antagonist flumazenil enhances the maximum number of benzodiazepine binding sites

Dubravka Švob Štrac

Life Sciences, 2004

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6-Methyl-3′-bromoflavone, a High-Affinity Ligand for the Benzodiazepine Binding Site of the GABAA Receptor with Some Antagonistic Properties

Luciana Izquierdo

Biochemical and Biophysical Research Communications, 1999

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