Transactivation-deficient Delta TA-p73 Inhibits p53 by Direct Competition for DNA Binding. IMPLICATIONS FOR TUMORIGENESIS (original) (raw)

P53-FAMILY Proteins and Their Regulators: Hubs and Spokes in Tumor Suppression

Andrea Lunardi

Cell Death & Differentiation, 2010

View PDFchevron_right

p63 and p73, members of the p53 gene family, transactivate PKCδ

alessandro terrinoni

Biochemical Pharmacology, 2006

View PDFchevron_right

ΔN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53

Gerald Verhaegh

Oncogene, 2002

View PDFchevron_right

Supplementary Table 2 from Comparison of the Effect of Mutant and Wild-Type p53 on Global Gene Expression

Dan Longo

2023

View PDFchevron_right

EXPRESSION OF p53 IN HUMAN BREAST CANCER

Veaceslav Fulga

Biological Markers in Fundamental and Clinical Medicine (collection of abstracts), 2017

View PDFchevron_right

p53 Gene Replacement for Cancer&Interactions with DNA Damaging Agents

Susan Grammer

Acta Oncologica, 2001

View PDFchevron_right

P53: A Molecular Marker for the Detection of Cancer

Nikolina Vlatkovic

Expert Opinion on Medical Diagnostics, 2008

View PDFchevron_right

Complex analysis of the p53 tumor suppressor in lung carcinoma

Jana Smardova

Oncology Reports, 2015

View PDFchevron_right

Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes

Anindita Das

Oncogene, 2004

View PDFchevron_right

p73 Function Is Inhibited by Tumor-Derived p53 Mutants in Mammalian Cells

Charles J DiComo

View PDFchevron_right

On the shoulders of giants: p63, p73 and the rise of p53

Daniel Caput

Trends in Genetics, 2002

View PDFchevron_right

P53 in Breast Cancer: Mutation and Countermeasures

Sumit Kumar

Frontiers in Bioscience, 2007

View PDFchevron_right

Repair or perish – the role of p53 protein in a cell’s life

Barbara Pieńkowska-grela

Nowotwory. Journal of Oncology, 2019

View PDFchevron_right

Mutated and non-mutated TP53 as targets in the treatment of leukaemia

hernan concha

British Journal of Haematology, 2008

View PDFchevron_right

Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain

Loretta Tuosto

2009

View PDFchevron_right

Transactivation-deficient DeltaTA-p73 acts as an oncogene

Brigitte Pützer

Cancer research, 2002

View PDFchevron_right

P53 Re-Expression Inhibits Proliferation and Restores Differentiation of Human Thyroid Anaplastic Carcinoma Cells

S. Filetti

Oncogene, 1997

View PDFchevron_right

Tumor Suppressor Protein p53 Recruits Human Sin3B

leena vig

2011

View PDFchevron_right

p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities

Daniel Caput

Molecular Cell, 1998

View PDFchevron_right

P53 at the Crossroads Between Cancer and Neurodegeneration

Cristina Lanni

Free Radical Biology and Medicine, 2012

View PDFchevron_right

Role of the p53-homologue p73 in E2F1-induced apoptosis

Brigitte Pützer

Nature Genetics, 2000

View PDFchevron_right

Transactivation-deficient p73α (p73Δexon2) inhibits apoptosis and competes with p53

Michael McGuckin

Oncogene, 2001

View PDFchevron_right

Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets

Tali Haran

Nucleic Acids Research, 2010

View PDFchevron_right

Mutations in p53, p53 protein overexpression and breast cancer survival

Tara Kalra

Carolina Digital Repository (University of North Carolina at Chapel Hill), 2009

View PDFchevron_right

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

Alan Fersht

Oncogene, 2000

View PDFchevron_right

Translational approaches targeting the p53 pathway for anti-cancer therapy

Frank Essmann

British Journal of Pharmacology, 2012

View PDFchevron_right

P53 Isoforms Δ133P53 and P53Β Are Endogenous Regulators of Replicative Cellular Senescence

Giang Nguyen

Nature Cell Biology, 2009

View PDFchevron_right

Transactivation-de®cient p73a (p73Dexon2) inhibits apoptosis and competes with p53

Ygal Haupt

Oncogene, 2001

View PDFchevron_right

TAF6δ orchestrates an apoptotic transcriptome profile and interacts functionally with p53

László Tora

BMC Molecular Biology, 2010

View PDFchevron_right

DNA binding and 3′–5′ exonuclease activity in the murine alternatively-spliced p53 protein

Tali Haran

Oncogene, 2002

View PDFchevron_right

A Subset of Tumor-Derived Mutant Forms of p53 Down-Regulate p63 and p73 through a Direct Interaction with the p53 Core Domain

Maria Lokshin

Molecular and Cellular Biology, 2001

View PDFchevron_right

p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core

Sergey Zotchev

Nucleic Acids Research, 2000

View PDFchevron_right

Analysis of the Binding of p53 to DNAs Containing Mismatched and Bulged Bases

Natalya Degtyareva

Journal of Biological Chemistry, 2001

View PDFchevron_right

Early stages of p53-induced apoptosis are reversible

Jon Geske

Cell Death & Differentiation, 2001

View PDFchevron_right

Physical and Functional Interaction between p53 and the Werner's Syndrome Protein

Gianni Cesareni

Journal of Biological Chemistry, 1999

View PDFchevron_right