Can Nutritional Supports Beneficial in Other Viral Diseases Be Favorable for COVID-19? (original) (raw)
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Background: The novel coronavirus (COVID-19) is considered as the most life-threatening pandemic disease during the last decade. The individual nutritional status, though usually ignored in the management of COVID-19, plays a critical role in the immune function and pathogenesis of infection. Accordingly, the present review article aimed to report the effects of nutrients and nutraceuticals on respiratory viral infections including COVID-19, with a focus on their mechanisms of action. Methods: Studies were identified via systematic searches of the databases including PubMed/ MEDLINE, ScienceDirect, Scopus, and Google Scholar from 2000 until April 2020, using keywords. All relevant clinical and experimental studies published in English were included. Results: Protein-energy malnutrition (PEM) is common in severe respiratory infections and should be considered in the management of COVID-19 patients. On the other hand, obesity can be accompanied by decreasing the host immunity. Therefo...
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In December 2019, a novel severe acute respiratory syndrome coronavirus (SARS-Cov2) emerged in Wuhan, China, which is followed by the global pandemic of coronavirus disease (COVID-19). So far, COVID-19 is affecting the health and lives of millions of people and impacting economic dramatically in more than 180 countries worldwide. Since the outbreak of COVID-19, potential medical treatments and vaccines have been developed and tested by biotech and pharmaceutical companies. Nutrition is critical for prevent and recovery of diseases. Multiple nutrients have been considered as potential means to help in the combat against COVID-19. In addition, nutritional considerations are also important for people to maintain healthy when their daily dietary behaviors and physical activities are altered by COVID-19. Here, we tried to summarize potential medical treatments, vaccines, and important nutrients affecting outcomes of COVID-19 patients. In addition, we discussed the influences of dietary ...
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The novel coronavirus diseases 2019 (COVID-19) has unfolded an unprecedented worldwide public health emergency with disastrous economic consequences. Around 12 million coronavirus cases have already been identified with over half a million death. Despite numerous efforts by government as well as international organizations, these numbers are still increasing with a surprising rate. Although urgent and absolutely necessary, a reliable therapeutic or vaccine is still elusive and this status quo may remain for an uncertain period of time. Taken that into account, boosting up adaptive immunity through nutritional interventions may help subside this epidemic and save many lives. This review focuses on the nexus between a balanced diet and adaptive immunity, particularly, how poor diet may lead to compromised immunity resulting in susceptibility to the viral infections. Additionally, we discuss how nutrients (vitamins, minerals, trace elements) could be used as a tool to modulate immune r...
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International journal of applied chemical and biological sciences, 2021
A novel coronavirus (SARS-CoV-2) has rapidly spread from a regular seafood market in Wuhan, China to more than 200 countries, globally infecting millions of people with a dangerous pneumonia like fatal conditions. Depending upon the immunity of individual, the severity of infection and its viral load, symptoms varied from mild to severe leading to Acute respiratory distress syndrome (ARDS) and sepsis. Thus, in order to combat the symptoms and reduce the death rate it was accepted globally to use pre-used anti-viral, anti-malaria, antiinflammatory and various immune-boosters drugs. The drugs are undergoing clinical trials to increase its safety efficiency simultaneously suppressing viral infection. Along with drugs, the micronutrients like vitamin C, vitamin D and Zinc are also used as immune-boosters in combination with drugs to increase the efficiency rate and reduce the side effects. Following review, describes the clinical trials currently undergoing and importance of micro-and macro nutrients to overcome hyper-inflammation and cytokine storm generated by SARS-CoV-2.
COVID-19: Role of Nutrition and Supplementation
Nutrients
At the end of 2019, a new coronavirus (COVID-19) appeared on the world scene, which mainly affects the respiratory system, causing pneumonia and multi-organ failure, and, although it starts with common symptoms such as shortness of breath and fever, in about 2–3% of cases it leads to death. Unfortunately, to date, no specific treatments have been found for the cure of this virus and, therefore, it is advisable to implement all possible strategies in order to prevent infection. In this context, it is important to better define the role of all behaviors, in particular nutrition, in order to establish whether these can both prevent infection and improve the outcome of the disease in patients with COVID-19. In the literature, it is widely shown that states of malnutrition, overweight, and obesity negatively affect the immune system, leading to viral infections, and several studies have shown that nutritional interventions can act as immunostimulators, helping to prevent viral infections...
Potential Efficacy of Nutrient Supplements for Treatment or Prevention of COVID-19
Journal of Dietary Supplements
COVID-19 (COronaVIrus Disease of 2019), the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents an ongoing global health challenge and the deadliest epidemic coronavirus outbreak to date. Early sequencing of the viral genome and knowledge from past coronavirus outbreaks (SARS-CoV-1 and Middle East Respiratory Syndrome, MERS) has led to rapid advances in knowledge of how the virus spreads and infects human hosts. Unfortunately, advancing knowledge has not yet produced a treatment that substantially lowers morbidity or mortality and only recently resulted in the development of a vaccine that prevents severe disease. Mounting evidence supports the notion that dietary supplementation of key essential nutrients may contribute to the body's defenses against infection as well as bolster the body's responses to infection. Evidence supporting the potential beneficial roles of vitamin C, vitamin D, zinc, and B3 vitamins is reviewed here, revealing a combination of basic research elucidating underlying mechanisms of action, preclinical studies and human intervention studies has led to the proliferation of registered clinical trials on COVID-19. Overall, the data suggest this collection of nutrients has a promising impact on reducing the risk and/or severity of COVID-19, although firm conclusions await the results of these trials.
How Nutrition can help to fight against COVID-19 Pandemic
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Currently Covid-19 pandemic is a leading challenge across the globe. It is mandatory to attain and maintain good nutritional status to fight against virus. Nutritional status of individual is affected by several factors such as age, sex, health status, life style and medications. Nutritional status of individuals has been used as resilience towards destabilization during this COVID-19 pandemic. Optimal nutrition and dietary nutrient intake impact the immune system, therefore the only sustainable way to survive in current context is to strengthen the immune system. There is no evidence found that supplement can cure the immune system except Vit C, which is one of the best way to improve immune system. A proper diet can ensure that the body is in proper state to defeat the virus. However along with the dietary management guidelines the food safety management and good food practices is compulsory. This article explores the importance of nutrition to boost immunity and gives some profes...
Nutritional Therapy in COVID-19 Management
Kompass Nutrition & Dietetics, 2020
This review deals with the relationship among nutrition, the immune system, and coronavirus disease 2019 (COVID-19). The influence of nutrients and bioactive molecules present in foodstuffs on immune system activity, the influence of COVID-19 on the nutritional status of the patients, and the dietary recommendations for hospitalized patients are addressed. Deficient nutritional status is probably due to anorexia, nausea, vomiting, diarrhea, hypoalbuminemia, hypermetabolism, and excessive nitrogen loss. There is limited knowledge regarding the nutritional support during hospital stay of COVID-19 patients. However, nutritional therapy appears as first-line treatment and should be implemented into standard practice. Optimal intake of all nutrients, mainly those playing crucial roles in immune system, should be assured through a diverse and well-balanced diet. Nevertheless, in order to reduce the risk and consequences of infections, the intakes for some micronutrients may exceed the rec...
COVID-19 and Impact of Nutrition
Life and Science
Coronavirus disease (COVID-19) is an infectious disease that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has affected the entire world. The clinical course of infection varies from asymptomatic to mild symptoms to life threatening conditions in affected individuals. An unbalanced immune response is responsible for many complications and even death in severe cases. Poor nutritional status is a major risk factor for infection as it makes the patient immunocompromised. A good dietary pattern boost immune system in combating infections. In this review, the role of various dietary patterns, individual vitamins and trace elements will be considered. The link between diet and COVID-19 has yet to be established. However, findings from previous studies on respiratory tract infections have shown that diet plays an important role in the management and prevention of infections.