[Neonatal sepsis morbidity and mortality in a tertiary care hospital] (original) (raw)
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Sepsis Code: dodging mortality in a tertiary hospital
Revista Española de Quimioterapia, 2021
Background. In the hospital of La Princesa, the “Sepsis Code” (CSP) began in 2015, as a multidisciplinary group that provides health personnel with clinical, analytical and organizational tools, with the aim of the detection and early treatment of patients with sepsis. The objective of this study is to evaluate the impact of CSP implantation on mortality and to determine the variables associated with an increase in it. Material and methods. A retrospective analytical study of patients with CSP alert activation from 2015 to 2018 was conducted. Clinical-epidemiological variables, analytical parameters, and severity factors such as admission to critical care units (UCC) and the need for amines were collected. Statistical significance was established at p < 0.05. Results. We included 1,121 patients. The length of stay was 16 days and 32% required admission to UCC. Mortality showed a statistically significant linear downward trend from 24% in 2015 to 15% in 2018. The predictive mortal...
Perinatal risk factors in neonatal sepsis. Three-year study
2018
Introducción: las Unidades de Cuidados Neonatales son áreas de atención dinámica que reciben pacientes con disímiles factores de riesgo que predisponen a la sepsis. Objetivo: determinar la incidencia de los factores de riesgo perinatales en la aparición de sepsis de inicio precoz en los recién nacidos atendidos en el Servicio de Neonatología del Hospital Universitario Ginecoobstétrico “Mariana Grajales” de Villa Clara durante los años 2015 y 2017. Métodos: se realizó un estudio analítico de grupos comparativos con elementos de enfoque mixto. La población estudio estuvo conformada por 312 neonatos con factores de riesgo. Resultados: predominaron los recién nacidos a término, masculinos y con peso mayor o igual a 2 500 gramos; sin embargo, la prematuridad y el bajo peso tuvieron asociación causal con la sepsis de aparición temprana. Los factores de riesgo estratificados en pacientes con sepsis neonatal temprana fueron, por orden de frecuencia: el tiempo de rotura de membrana mayor de ...
Factores asociados al desarrollo de sepsis neonatal en un hospital infantil de tercer nivel en Colombia, 2020
Introduction: Neonatal sepsis (SN) causes high morbidity and mortality in this population; in South America its incidence is between 3.5 to 8.9 per 1,000 live births. This might be due to the fact that, although the “gold standard” for diagnostic confirmation is blood culture, it lacks sensitivity because of its low isolation rate. Therefore, it is essential to correctly identify risk factors associated with its presentation in order to increase the probability of making a diagnosis and timely treatment. Objective: To identify the factors associated with the development of bacterial sepsis in newborns admitted to the Napoleon Franco Pareja Children's Hospital in the city of Cartagena. Methods: Cross-sectional study of the medical records of hospitalized newborns with suspected early or late SN. Sociodemographic variables of newborn, mother, clinical presentation and treatment were measured. Raw and adjusted OR were estimated by logistic regression of clinical variables as causal of SN. Results: Sepsis was present in 19.1 % of the 230 suspected newborns, of these, 63.6 % were identified as Sthapylococcus coagulase negative spp. The adjusted association analysis showed as risk factors for SN, being a teenage mother with OR = 3.21 (95 % CI: 1.13 - 9.18) and high CRP with OR = 2.41 (95 % CI 1.17- 4.99). Conclusion: Neonatal sepsis and its diagnosis continue to be a major clinical challenge in developing countries. The present study suggests that the children of an adolescent mother and the elevated CRP are related to a positive diagnosis as methods prior to blood cultures, which continue to be the gold standard despite their low performance. Keywords: neonatal sepsis; risk factors; cross-sectional studies; C-reactive protein.
Maternal risks associated with early neonatal sepsis.pdf
Neonatal infection is a clinical syndrome that constitutes an important cause of neonatal morbidity and mortality. According to the time of onset, sepsis may be early or late (after 72 hours of life), considered primarily as intrahospital. It is identified maternal factors related to early neonatal sepsis in the neonatology department of the General Hospital "Dr. AgostinhoNeto "during 2014. Analytical research was carried out on cases and controls whose universe consisted of 38 neonates diagnosed with early sepsis and 76 controls (births up to 2 days before or after the cases) and who were admitted to the neonatology department, Information was obtained from the mothers' case histories and controls, risk factors were assessed through the odds ratio. Predominant adolescent mothers, history of vaginal infection, premature rupture of the membrane, the history of dystocic delivery.
Risk factors associated with early sepsis in neonates.pdf
Neonatal infection is a clinical syndrome that is an important and frequent cause of morbidity and mortality in the neonatal period. Depending on the time of onset, sepsis may be early or late. Objective: To identify some risk factors present in neonates associated with early sepsis in the neonatal clinic at the General Teaching Hospital Agostino Neto during 2014. Method: A case-control study was conducted in which 38 infants diagnosed with sepsis Preterm neonatal and 76 unpaired controls (births up to 2 days before or after the cases) and who were admitted to the neonatology service, the information was obtained from the case histories and controls, the factors risk were evaluated through the odds ratio. Results: There was a predominance of cases with a history of dystocic delivery; Preterm birth, low birth weight, in addition to the history of having received mechanical ventilation, these elements were associated with early-onset sepsis. Conclusions: an adequate control of risk factors in newborns can guarantee a decrease in the occurrence of neonatal sepsis in particular and improve the quality of life of neonates.
Revista Ciencias Biomédicas
Introducción: La sepsis neonatal causa una alta morbimortalidad en esta población; en América del Sur su incidencia está entre 3,5 a 8,9 por cada 1000 nacidos vivos. Esto podría obedecer a que pesar de que el “gold estándar” para la confirmación diagnóstica es el hemocultivo, carece de sensibilidad por su baja tasa de aislamiento. Por lo anterior, se hace indispensable identificar de manera acertada factores de riesgo asociados a su presentación para con ello aumentar la probabilidad de realizar un diagnóstico y manejo oportuno.Objetivo: Identificar los factores asociados al desarrollo de sepsis bacteriana en los recién nacidos que ingresaron al Hospital Infantil Napoleón Franco Pareja en Cartagena. Métodos: estudio de corte transversal con las historias clínicas de recién nacidos hospitalizados con sospecha de sepsis neonatal temprana o tardía. Se midieron variables sociodemográficas del recién nacido, de la madre, la presentación clínica y el tratamiento. Se estimaron odds ratios ...
2015
Neonatal sepsis has a high death rate. Evaluate the characteristics of its clinical presentation allows to establish control measures. Objectives: To describe the panorama of sepsis events in a neonatal therapy unit, with regard to their classifi cation, early or late, and causal agents. Analyze the behavior of infection according to the newborns degree of maturity. Material and methods: We recovered data from clinical records of all the events of sepsis in a private care NICU during seven years and we analyzed them. For this study, we defi ned sepsis according to the criteria of the Centers for Disease Control and Prevention (CDC) in the United States, and reviewed the results of isolates of pathogens. Results: A total 712 episodes of neonatal sepsis were identifi ed, 650 (91.3%) corresponded to early sepsis and 62 (8.7%) to late sepsis. There were 31 isolates of pathogens, 12 (1.8%) among the 650 cases of early sepsis and 19 (30.6%) of the 62 neonates with late sepsis (p < 0.00...