Synthesis, Antibacterial Studies and Crystal Structures of Tridentate Schiff Base Ligand and It’s Cobalt(III) Complex (original) (raw)
Related papers
Polyhedron, 2013
Ligand, HL, 2-((2-(benzylthio)phenylimino)methyl)phenol, upon reaction with Co(NO 3) 3 Á6H 2 O, Ni(OAc) 2-Á4H 2 O and PdCl 2 separately afforded complexes [(L) 2 Co]NO 3 (1), [(L) 2 Ni] (2) and [(L)PdCl] (3) respectively. The new complexes were characterized by usual spectroscopic studies like UV-Vis, IR and NMR and authenticated by X-ray structure determination on [(L) 2 Co]NO 3 , [(L) 2 Ni]. The analysis of crystal structures revealed that in all the complexes the ligand HL binds the metal center as uni-negative anion; L À dissociating phenolic proton and offers (O, N, S) tridentate binding mode to the metal. The compound [Co(L) 2 ]-NO 3 is tested for in vitro antibacterial activity. Complex 3, acts as a catalyst in Heck reaction for a number of substrates. Complexes 1 and 2 exhibited a quasi reversible oxidative responses at 0.97 and 0.85 V, respectively, versus SCE. The electronic spectra and redox properties of the complexes have been explained with DFT computation.
Two new Schiff base complexes of cobalt(III) viz. [Co(L)(L 1)(NCS)]ClO 4 (1) and [Co(L 2)(N 3)] 2 Á4H 2 O (2), where L = propane-1,2-diamine, L 1 = 2-[N-(2-aminopropyl)ethanimidoyl]phenolate and L 2 = 2,2 0-[propane-1,2-diylbis(nitriloeth-1-yl-1-ylidene)]diphenolate ion, have been prepared and characterized. The syntheses have been achieved by reacting cobalt perchlorate either with the diamine (L) and 2-hydroxyacetophenone together or with their Schiff base H 2 L 2 in presence of the respective pseudohalide. The same synthetic system has yielded two complexes of different nuclearity in presence of two different pseudohalides i.e. the mononuclear 1 with thiocyanate and the binuclear 2 with azide ion. The tridentate (L 1) and tetradentate (L 2) Schiff base anions were formed in situ to bind the Co(III) ion in case of the template syntheses. The complexes have been characterized by elemental analysis, IR spectroscopy and single crystal X-ray diffraction studies. Structural studies reveal that the central Co(III) ions in both the complexes 1 and 2 adopt distorted octahedral geometry and weak intermolecular H-bonding or p.. .p interactions are operative to bind the complex units in the solid state. The antibacterial activity of the complexes and related compounds has been tested against some Gram(+) and Gram(À) bacteria.
2018
A series of six new mononuclear Schiff base complexes, <b>1</b>–<b>6</b> of cobalt(III) of the general formula, [CoLX] or its adduct with methanol, is reported. The pentadentate Schiff base ligand (H<sub>2</sub>L) was obtained by the condensation of <i>N</i>-(3-aminopropyl)-<i>N</i>-methylpropane-1,3-diamine with 1-(2-hydroxyphenyl)ethanone (H<sub>2</sub>L<sup>1</sup>) or 1-(2-hydroxyphenyl)propan-1-one (H<sub>2</sub>L<sup>2</sup>). X stands for the pseudohalides, N<sub>3</sub><sup>–</sup>, N(CN)<sub>2</sub><sup>−</sup> , and NCS<sup>–</sup>. The complexes have been synthesized by the reaction of equimolar amounts of cobalt(II) nitrate with H<sub>2</sub>L<sup>1</sup> or H<sub>2</sub>L<sup>2</sup> in the presence of the respective pseudohalide in methanol medium. All the ...
Microbial pathogenesis, 2017
A novel Co(III) complex, [Co(L)(Imi)3]Cl incorporating 2-((3-methoxy-2-oxidobenzylidene)amino)-4-methylphenolate (L(2-)), as a dibasic deprotonated Schiff base ligand and imidazole (Imi) was synthesized and fully characterized using physicochemical and spectroscopic techniques including elemental analysis, conductance measurement, FT-IR, UV-Vis and X-ray single crystal diffraction. As the conductivity data showed, the synthesized complex had a 1:1 ionic nature. The structure of the complex was found to be distorted octahedral in which, O/N donor atoms of the Schiff base ligand and N atoms of three imidazole groups were involved. Antimicrobial activity of the Co(III) complex as well as the its parent Schiff base ligand against two Gram-positive bacteria (S. Aureus and M. luteus), two Gram-negative bacteria (E. coli and P. aeruginosa) and a fungus (C. Albicans) was studied. Moreover, the antimicrobial activity of [Co(L)(Imi)3]Cl was investigated using molecular docking of the complex ...
Zeitschrift für anorganische und allgemeine Chemie, 2021
Mononuclear chelates of Cr(III), Mn(II), Fe(III), Ni(II), Cu(II), Zn(II) and Cd(II) resulted from new tridentate Schiff base ligand, 4‐((1‐(5‐acetyl‐2,4‐dihydroxyphenyl)ethylidene)amino)‐1,5‐dimethyl‐2‐phenyl‐1H‐pyrazol‐3(2H)‐one, were synthesized. Metal to ligand ratio was found to be1 : 1, which was revealed via elemental analysis and characterized via various spectroscopic tools. IR has point out that the coordination of the ligand towards the metal ions was carried out via NOO donor atoms. UV‐Vis, 1H NMR spectral data, molar conductivity measurements, BET surface area, melting points and theoretically through density function theory were used such as characterizing techniques in supporting further interpretation of the complexes structures. The complexes were octahedral except Cu(II) and Ni(II) complexes were tetrahedral as suggested from the magnetic moment measurement. The complexes were found to have surface area, pore volume and particle radius of 23–176 m2 g−1, 0.02‐0.33 cc...