Fisetin induces apoptosis through mitochondrial apoptosis pathway in human uveal melanoma cells (original) (raw)
Fisetin Deters Cell Proliferation, Induces Apoptosis, Alleviates Oxidative Stress and Inflammation in Human Cancer Cells, HeLa
nazia afroze
International Journal of Molecular Sciences, 2022
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Inhibition of Human Melanoma Cell Growth by the Dietary Flavonoid Fisetin Is Associated with Disruption of Wnt/β-Catenin Signaling and Decreased Mitf Levels
Adeel Ahmad
Journal of Investigative …, 2011
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The Flavonol Isoquercitrin Promotes Mitochondrial-Dependent Apoptosis in SK-Mel-2 Melanoma Cell via the PI3K/AKT/mTOR Pathway
Rona Lizardo
Nutrients, 2020
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Fisetin: A Dietary Antioxidant for Health Promotion
Nihal Ahmad
Antioxidants & Redox Signaling, 2013
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Enhancement of P53-Mutant Human Colorectal Cancer Cells Radiosensitivity by Flavonoid Fisetin
Yi-jang Lee
International Journal of Radiation Oncology*Biology*Physics, 2010
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N -acetyl-L -cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells
Shing-chuan Shen
Molecular Carcinogenesis, 2013
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A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF- B-signaling pathways
Hasan Mukhtar
Carcinogenesis, 2008
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Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
Jameel Alafifi
Global Medical Genetics
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Fisetin: A bioactive phytochemical with potential for cancer prevention and pharmacotherapy
Hardeep S Tuli
Life sciences, 2017
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Genotoxic and Cytotoxic Activity of Fisetin on Glioblastoma Cells
Bernd Kaina
Anticancer Research/Anticancer research, 2024
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Phosphoprotein levels, MAPK activities and NFκB expression are affected by fisetin
Maikel Peppelenbosch
Journal of Enzyme Inhibition and Medicinal Chemistry, 2007
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Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter
Byoung-mog Kwon
Carcinogenesis, 2015
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Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease
ＷＥＩＴＩＮＧ ＬＩＵ
Biochemical Pharmacology, 2002
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Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics
KANAN PANCHAL
Pharmaceuticals
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Zeaxanthin Induces Apoptosis in Human Uveal Melanoma Cells through Bcl-2 Family Proteins and Intrinsic Apoptosis Pathway
Richard B Rosen
Evidence-Based Complementary and Alternative Medicine, 2013
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Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation
Paavo Honkakoski
Scientific Reports, 2015
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Flavonoid-induced apoptotic cell death in human cancer cells and its mechanisms
Preethi Vetrivel
Journal of Biomedical Translational Research
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In-vitro anti-proliferative and anti-oxidant activity of galangin, fisetin and quercetin: Role of localization and intermolecular interaction in model membrane
Marieta Costache
European Journal of Medicinal Chemistry, 2014
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Cancer chemopreventive role of fisetin: Regulation of cell signaling pathways in different cancers
Baojun Xu
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Fisetin Protects HaCaT Human Keratinocytes from Fine Particulate Matter (PM2.5)-Induced Oxidative Stress and Apoptosis by Inhibiting the Endoplasmic Reticulum Stress Response
Dumindu Kavinda, Neelaka Molagoda
Antioxidants
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Antiproliferative Mechanisms of a Polyphenolic Combination of Kaempferol and Fisetin in Triple-Negative Breast Cancer Cells
Dr. Rashid Ayub
International Journal of Molecular Sciences
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Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line–A comparative study
sivagami gunasekaran
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The Flavonoid Luteolin Increases the Resistance of Normal, but Not Malignant Keratinocytes, Against UVB-Induced Apoptosis
Lieve Declercq
Journal of Investigative Dermatology, 2010
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The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
Emran Habibi
Frontiers in Pharmacology
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Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers
Jean Fotie
Bioorganic Chemistry, 2021
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The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells
You-cheng Hseu
Cancers
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Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells
Anu Kauppinen
The Journal of nutritional biochemistry, 2017
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TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of …
Peter Hersey
The Journal of …, 2000
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Enhancement of induced apoptosis in human melanoma A375 by a combination of natural compounds
Ali Al Shawi
academicjournals.org
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Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential
Sardul Sandhu
Biomolecules, 2019
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Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint
Gary Gorbsky
…, 2009
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