Does the Serum Testosterone Level Have a Relation to Coronary Artery Disease in Elderly Men? (original) (raw)

2011, Current Gerontology and Geriatrics Research

Background. The low serum level of testosterone in the elderly subjects may contribute to coronary artery disease (CAD). Our aim is to study serum levels of free testosterone in elderly men with CAD.Subjects and Methods. This study was conducted on 100 elderly males with CAD, one half of them was presented with ACS (with mean age year), and the other half was presented with stable CAD (with mean age year), in addition to 50 apparently healthy elderly males (with mean age year) as a control group. We detected the levels of serum free testosterone, cortisol, fibrinogen, plasminogen activator inhibitor-1(PAI-1), high sensitive C-reactive protein(hsCRP), interleukin-6(IL-6).Results. Cases with CAD had significant lower values of free testosterone and HDL-c, but they had significant higher values of cortisol, fibrinogen, PAI-1, IL-6, hsCRP, in comparison to control group. Cases with ACS had significant higher values of cortisol, hsCRP, IL-6, fibrinogen, PAI-1, total cholesterol and BMI m...