High-Magnitude, Virus-Specific CD4 T-Cell Response in the Central Nervous System of Coronavirus-Infected Mice (original) (raw)
CD4 T-Cell-Mediated Demyelination Is Increased in the Absence of Gamma Interferon in Mice Infected with Mouse Hepatitis Virus
Stanley Perlman
Journal of Virology, 2002
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Bystander CD4 T cells do not mediate demyelination in mice infected with a neurotropic coronavirus
Stanley Perlman
Journal of Neuroimmunology, 2003
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Perforin and Gamma Interferon-Mediated Control of Coronavirus Central Nervous System Infection by CD8 T Cells in the Absence of CD4 T Cells
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CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity
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Murine hepatitis virus-4 (strain JHM)-induced neurologic disease is modulated in Vivo by monoclonal antibody
Robert Knobler
Virology, 1984
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Pathogenesis of acute and chronic central nervous system infection with variants of mouse hepatitis virus, strain JHM
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Cutting Edge: CD8 T Cell-Mediated Demyelination Is IFN- Dependent in Mice Infected with a Neurotropic Coronavirus
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Contributions of the Viral Genetic Background and a Single Amino Acid Substitution in an Immunodominant CD8+T-Cell Epitope to Murine Coronavirus Neurovirulence
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Characterization of brain-infiltrating mononuclear cells during infection with mouse hepatitis virus strain JHM
Karin Nitiss
Journal of Neuroimmunology, 1991
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Cytokine induction in vitro in mouse brain endothelial cells and astrocytes by exposure to mouse hepatitis virus (MHV-4, JHM)
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Advances in experimental medicine and biology, 1993
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Current Opinion in Microbiology, 2001
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The role of gamma interferon in infection of susceptible mice with murine coronavirus, MHV-JHM
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Immune response to a murine coronavirus: Identification of a homing receptor-negative CD4+ T cell subset that responds to viral glycoproteins
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Antibody-Mediated Protection against Cytotoxic T-Cell Escape in Coronavirus-Induced Demyelination
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The Role of CD4 and CD8 T Cells in MHV-JHM-Induced Demyelination
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Advances in Experimental Medicine and Biology, 2001
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Differential Antigen Recognition by T Cells from the Spleen and Central Nervous System of Coronavirus-Infected Mice
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Virology, 1996
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De Novo Recruitment of Antigen-Experienced and Naive T Cells Contributes to the Long-Term Maintenance of Antiviral T Cell Populations in the Persistently Infected Central Nervous System
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The Journal of Immunology, 2009
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Mouse hepatitis virus neurovirulence: evidence of a linkage between S glycoprotein expression and immunopathology
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Virus-Specific Antibody, in the Absence of T Cells, Mediates Demyelination in Mice Infected with a Neurotropic Coronavirus
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The American Journal of Pathology, 2005
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Gamma Interferon Is Critical for Neuronal Viral Clearance and Protection in a Susceptible Mouse Strain following Early Intracranial Theiler's Murine Encephalomyelitis Virus Infection
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Understanding the Cellular and Molecular Mechanism of Mouse Hepatitis Virus Induced Neuroinflammation and Demyelination in an Experimental Mice Model
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Infection with Cytotoxic T-Lymphocyte Escape Mutants Results in Increased Mortality and Growth Retardation in Mice Infected with a Neurotropic Coronavirus
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Macrophage Infiltration, but Not Apoptosis, Is Correlated with Immune-Mediated Demyelination following Murine Infection with a Neurotropic Coronavirus
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CD4 T Cells Promote CD8 T Cell Immunity at the Priming and Effector Site during Viral Encephalitis
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Importance of the Antibody Response in the Outcome of Virus-Induced Diseases of the Central Nervous System
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Kinetics of Cytokine mRNA Expression in the Central Nervous System Following Lethal and Nonlethal Coronavirus-Induced Acute Encephalomyelitis
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Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection
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T cell mediated suppression of neurotropic coronavirus replication in neural precursor cells
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Pathogenesis of murine coronavirus in the central nervous system
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Role of IFN-γ responsiveness in CD8 T cell-mediated viral clearance and demyelination in coronavirus-infected mice
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Bystander CD8 T Cell-Mediated Demyelination After Viral Infection of the Central Nervous System
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Recruitment Kinetics and Composition of Antibody-Secreting Cells Within the Central Nervous System Following Viral Encephalomyelitis
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Persistent viral infection elevates central nervous system MHC class I through chronic production of interferons
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Axonal Damage Is T Cell Mediated and Occurs Concomitantly with Demyelination in Mice Infected with a Neurotropic Coronavirus
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Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus
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Journal of virology, 1997
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