Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant mice (original) (raw)

Loss of circadian rhythmicity in aging mPer1-/-mCry2-/- mutant mice

Henrik Oster

Genes & Development, 2003

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Targeted modification of the Per2 clock gene alters circadian function in mPer2luciferase (mPer2Luc) mice

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mCRY1 and mCRY2 Are Essential Components of the Negative Limb of the Circadian Clock Feedback Loop

Kazuhiko Kume

Cell, 1999

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Targeted Disruption of the mPer3 Gene: Subtle Effects on Circadian Clock Function

David Weaver

Molecular and Cellular Biology, 2000

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Mammalian circadian autoregulatory loop: A timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription

Joseph S Takahashi

Neuron, 1998

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PER2 controls circadian periods through nuclear localization in the suprachiasmatic nucleus

Norio Ishida

Genes to Cells, 2007

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Restoration of circadian behavioural rhythms in a period null Drosophila mutant (per01) by mammalian period homologues mPer1 and mPer2

Weili Fu, Yasufumi Shigeyoshi

Genes to Cells, 2002

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Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2

Martha Vitaterna

1999

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Effects of constant light on circadian rhythmicity in mice lacking functional cry genes: dissimilar from per mutants

Kamiel Spoelstra

Journal of Comparative Physiology A, 2008

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Interacting Molecular Loops in the Mammalian Circadian Clock

Kazuhiko Kume

Science, 2000

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Circadian Clock Gene Per2 Is Not Necessary for the Photoperiodic Response in Mice

keisuke ikegami

PLoS ONE, 2013

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Restoration of Circadian Rhythmicity in Circadian Clock-Deficient Mice in Constant Light

Stephan Steinlechner

Journal of Biological Rhythms, 2006

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ORL1 receptor-mediated down-regulation of mPER2 in the suprachiasmatic nucleus accelerates re-entrainment of the circadian clock following a shift in the environmental light/dark cycle

Koji Teshima

Neuropharmacology, 2007

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The circadian cycle of mPER clock gene products in the suprachiasmatic nucleus of the Siberian hamster encodes both daily and seasonal time

Fran Ebling

European Journal of Neuroscience, 2000

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Multitissue Circadian Expression of Rat period Homolog (rPer2) mRNA Is Governed by the Mammalian Circadian Clock, the Suprachiasmatic Nucleus in the Brain

Norio Ishida

Journal of Biological Chemistry, 1998

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CHRONO and DEC1/DEC2 compensate for lack of CRY1/CRY2 in expression of coherent circadian rhythm but not in generation of circadian oscillation in the neonatal mouse SCN

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Scientific Reports

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Cryptochromes are critical for the development of coherent circadian rhythms in the mouse suprachiasmatic nucleus

Daisuke Ono, さと 本間

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Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

vivek kumar sharma

Molecular Cell, 2009

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Organ-specific development characterizes circadian clock gene Per2 expression in rats

さと 本間

AJP: Regulatory, Integrative and Comparative Physiology, 2014

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Postnatal Constant Light Compensates Cryptochrome1 and 2 Double Deficiency for Disruption of Circadian Behavioral Rhythms in Mice under Constant Dark

さと 本間

PLoS ONE, 2013

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Suppressed cellular oscillations in after-hours mutant mice are associated with enhanced circadian phase-resetting

Hugh Piggins, David Bechtold

The Journal of Physiology, 2013

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A positive role for PERIOD in mammalian circadian gene expression

Takeshi Todo

Cell reports, 2014

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Cryptochrome-Deficient Mice Lack Circadian Electrical Activity in the Suprachiasmatic Nuclei

Ines Chaves

Current Biology, 2002

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Circadian Oscillation ofBMAL1,a Partner of a Mammalian Clock GeneClock,in Rat Suprachiasmatic Nucleus

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Biochemical and Biophysical Research Communications, 1998

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Early doors ( Edo ) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking

Colby Sandate

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Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK

S. Rusconi

BMC Molecular Biology, 2008

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Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway

Kazuhiro Shimomura

2010

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Genetics and Neurobiology of Circadian Clocks in Mammals

Joseph S Takahashi

Cold Spring Harbor Symposia on Quantitative Biology, 2007

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In vivo role of phosphorylation of cryptochrome 2 in the mouse circadian clock

Takeshi Todo

Molecular and cellular biology, 2014

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Time after time: inputs to and outputs from the mammalian circadian oscillators

David Morse

Trends in Neurosciences, 2002

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Distinct Functions of Period2 and Period3 in the Mouse Circadian System Revealed by In Vitro Analysis

Shin Yamazaki

PLOS ONE, 2010

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The mammalian circadian system: a hierarchical multi-oscillator structure for generating circadian rhythm

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The Journal of Physiological Sciences

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Interaction of Per and Cry genes in the mammalian circadian clock

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