Absorption and release of zinc and copper ions by chitosan fibers (original) (raw)
2007, Journal of Applied Polymer Science
Chitosan fibers were treated with aqueous solutions of ZnCl2 and CuSO4·5H2O to prepare zinc and copper containing fibers, respectively. Significant weight gains were obtained as the zinc and copper ions were absorbed onto the fibers through chelation with the primary amine groups. The fibers were then placed in contact with aqueous solutions containing NaCl and water soluble proteins, respectively, to assess the release of zinc and copper ions. Results showed that the release of zinc and copper ions were affected by the treatment temperature, time, and the composition of the contacting media. More metal ions were released when the fibers were in contact with aqueous protein solutions than in NaCl solution, indicating the binding abilities of the protein molecules for zinc and copper ions. The zinc and copper containing fibers were tested for their antimicrobial effects against several species of bacteria commonly found in wound and skin. Results showed that these metal containing chitosan fibers had much stronger antimicrobial properties than the original chitosan fiber. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007
Related papers
Marine Drugs
Marine-derived chitosan (CS) is a cationic polysaccharide widely studied for its bioactivity, which is mostly attached to its primary amine groups. CS is able to neutralize reactive oxygen species (ROS) from the microenvironments in which it is integrated, consequently reducing cell-induced oxidative stress. It also acts as a bacterial peripheral layer hindering nutrient intake and interacting with negatively charged outer cellular components, which lead to an increase in the cell permeability or to its lysis. Its biocompatibility, biodegradability, ease of processability (particularly in mild conditions), and chemical versatility has fueled CS study as a valuable matrix component of bioactive small-scaled organic drug-delivery systems, with current research also showcasing CS’s potential within tridimensional sponges, hydrogels and sutures, blended films, nanofiber sheets and fabric coatings. On the other hand, renewable plant-derived extracts are here emphasized, given their poten...
Polymers
The Schiff base derivative (Ch-8Q) of chitosan (Ch) and 8-hydroxyquinoline-2-carboxaldehyde (8QCHO) was prepared and fibrous mats were obtained by the electrospinning of Ch-8Q/polylactide (PLA) blend solutions in trifluoroacetic acid (TFA). Complexes of the mats were prepared by immersing them in a solution of CuCl2 or FeCl3. Electron paramagnetic resonance (EPR) analysis was performed to examine the complexation of Cu2+(Fe3+) in the Ch-8Q/PLA mats complexes. The morphology of the novel materials and their surface chemical composition were studied by scanning electron microscopy (SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) and X-ray photoelectron spectroscopy (XPS). The performed microbiological screening demonstrated that in contrast to the neat PLA mats, the Ch-8Q-containing mats and their complexes were able to kill all S. aureus bacteria within 3 h of contact. These fibrous materials had efficiency in suppressing the adhesion of pathogeni...
Zinc Oxide and Copper Chitosan Composite Films with Antimicrobial Activity
Polymers, 2021
The role of the oral microbiome and its effect on dental diseases is gaining interest. Therefore, it has been sought to decrease the bacterial load to fight oral cavity diseases. In this study, composite materials based on chitosan, chitosan crosslinked with glutaraldehyde, chitosan with zinc oxide particles, and chitosan with copper nanoparticles were prepared in the form of thin films, to evaluate a new alternative with a more significant impact on the oral cavity bacteria. The chemical structures and physical properties of the films were characterized using by Fourier transform infrared spectroscopy (FTIR,) Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), elemental analysis (EDX), thermogravimetric analysis (TGA), X-ray diffraction (XRD), scanning electron microscopy (SEM), and contact angle measurements. Subsequently, the antimicrobial activity of each material was evaluated by agar diffusion tests. No differences were found in the hydrophilicity of the films with the...
Loading Preview
Sorry, preview is currently unavailable. You can download the paper by clicking the button above.