In silico modelling and molecular dynamics simulation studies of thiazolidine based PTP1B inhibitors (original) (raw)

In silico accounting of novel pyridazine analogues as h-PTP 1B inhibitors: pharmacophore modelling, atom-based 3D QSAR and docking studies

rajnish kumar

Medicinal Chemistry Research, 2014

View PDFchevron_right

Accounting of ligand-receptor interactions to explore and design novel architecture for PTP 1B inhibition: a legitimate approach

rajnish kumar

Journal of Chemometrics, 2012

View PDFchevron_right

Rationalizing Protein-Ligand Interactions for PTP1B Inhibitors Using Computational Methods

Sudhir Kulkarni

Chemical Biology & Drug Design, 2009

View PDFchevron_right

Molecular dynamics simulation study of PTP1B with allosteric inhibitor and its application in receptor based pharmacophore modeling

Nagakumar Bharatham

Journal of Computer-Aided Molecular Design, 2008

View PDFchevron_right

Pharmacophore Mapping, Docking and Three Dimensional QSAR Analysis of ((S)- γ -(Arylamino) Prolyl) Thiazolidine Compounds As A Potent and Stable DPP-IV Inhibitors

Swaraj Patil

2013

View PDFchevron_right

Ligand-based pharmacophore modeling; atom-based 3D-QSAR analysis and molecular docking studies of phosphoinositide-dependent kinase-1 inhibitors

venkata reddy gorla

Indian Journal of Pharmaceutical Sciences, 2012

View PDFchevron_right

Synthesis of protein tyrosine phosphatase 1B inhibitors: Model validation and docking studies

Amar Singh

Bioorganic & medicinal …, 2009

View PDFchevron_right

Prediction of enzyme inhibition and mode of inhibitory action based on calculation of distances between hydrogen bond donor/acceptor groups of the molecule and docking analysis: An application on the discovery of novel effective PTP1B inhibitors

Konstantinos Liaras, Phaedra (Faidra) Eleftheriou

View PDFchevron_right

Integrated use of ligand and structure based virtual screening, molecular dynamics, free energy calculation and ADME prediction for the identification of potential PTP1B inhibitors

Bharti Devi

View PDFchevron_right

Synergistic application of target structure-based alignment and 3D-QSAR study of protein tyrosine phosphatase 1B (PTP1B) inhibitors

Rajesh Singh

Medicinal Chemistry Research, 2011

View PDFchevron_right

Discovery of Novel DPP-IV Inhibitors as Potential Candidates for the Treatment of Type 2 Diabetes mellitus Predicted by 3D QSAR Pharmacophore Models, Molecular Docking and de novo Evolution

Azizullo Musoev

Molecules, 2019

View PDFchevron_right

Molecular docking and virtual screening for novel protein tyrosine phosphatase 1B (PTP1B) inhibitors

Suresh Babu

View PDFchevron_right

Molecular modeling studies of phenoxypyrimidinyl imidazoles as p38 kinase inhibitors using QSAR and docking☆

Achaiah Garlapati

European Journal of Medicinal Chemistry, 2008

View PDFchevron_right

Computational Methods in Cooperation with Experimental Approaches to Design Protein Tyrosine Phosphatase 1B Inhibitors in Type 2 Diabetes Drug Design: A Review of the Achievements of This Century

Alicia Hernández-Campos

Pharmaceuticals

View PDFchevron_right

Computational Modeling of Novel Phosphoinositol‐3‐kinase γ Inhibitors Using Molecular Docking, Molecular Dynamics, and 3D‐QSAR

Suparna Ghosh

Bulletin of the Korean Chemical Society, 2021

View PDFchevron_right

Design, Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2

Xian-Chao Cheng

International journal of molecular sciences, 2013

View PDFchevron_right

Protein structure-based drug design: from docking to molecular dynamics Paweł Sled z and Amedeo Caflisch

Yuying Huang

View PDFchevron_right

3D-QSAR, molecular docking and molecular dynamics studies of a series of RORγt inhibitors

Yunlong Gao

Journal of biomolecular structure & dynamics, 2014

View PDFchevron_right

Validation Of Formylchromane Derivatives As Ptp 1b Inhibitors By Pharmacophore Modeling, Atom Based 3d-Qsar And Docking Studies

RAJNISH KUMAR

Chemical Biology & Drug Design, 2013

View PDFchevron_right

Virtual screening, molecular dynamics, density functional theory and quantitative structure activity relationship studies to design peroxisome proliferator-activated receptor-γ agonists as anti-diabetic drugs

Nadia Afrin

Journal of Biomolecular Structure and Dynamics, 2020

View PDFchevron_right

Computational identification of potential dipeptidyl peptidase (DPP)-IV inhibitors: Structure based virtual screening, molecular dynamics simulation and knowledge based SAR studies

Virendra Nath Srivastav, MANISH Ramchandani

Journal of molecular structure, 2020

View PDFchevron_right

Virtual Screening of PEBP1 Inhibitors By Combining 2D/3D-QSAR Analysis, Hologram QSAR, Homology Modeling, Molecular Docking Analysis and Molecular Dynamic Simulations

TOUFIK Hamid

2021

View PDFchevron_right

In Silico Evaluation of Bioactive Compounds: Docking Simulations Based Enzyme-Inhibitor Interaction Compared with X-ray Models

Georgios Vlachopoulos

View PDFchevron_right

A mechanistic approach to explore novel HDAC1 inhibitor using pharmacophore modeling, 3D- QSAR analysis, molecular docking, density functional and molecular dynamics simulation study

sanjay choubey

Journal of Molecular Graphics and Modelling, 2016

View PDFchevron_right

Combined 3D-QSAR, molecular docking and dynamics simulations studies to model and design TTK inhibitors

Numan Yousaf

Frontiers in Chemistry

View PDFchevron_right

MOLECULAR DOCKING: AN EXPLANATORY APPROACH IN STRUCTURE-BASED DRUG DESIGNING AND DISCOVERY Review Article

International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)

International Journal of Pharmacy and Pharmaceutical Sciences, 2021

View PDFchevron_right

First report on 3D-QSAR and molecular dynamics based docking studies of GCPII inhibitors for targeted drug delivery applications

Chelvam Venkatesh

Journal of Molecular Structure, 2018

View PDFchevron_right

Advances in molecular modeling and docking as a tool for modern drug discovery

Ahmad F Eweas

View PDFchevron_right

DESIGN, IN SILICO DOCKING AND PREDICTIVE ADME PROPERTIES OF SOME THIAZOLIDINE-2, 4-DIONES DERIVATIVES AS PPARγ MODULATORS

International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)

International Journal of Pharmacy and Pharmaceutical Sciences, 2016

View PDFchevron_right

3D-QSAR Studies, Molecular Docking, Molecular Dynamic Simulation, and ADMET Proprieties of Novel Pteridinone Derivatives as PLK1 Inhibitors for the Treatment of Prostate Cancer

Mohamed El fadili

Life

View PDFchevron_right

Computational Study of Molecular Electrostatic Potential, Drug Likeness Screening and Structure-Activity/Property Relationships of Thiazolidine-2,4-Dione Derivatives

salim djekhaba

Journal of Bionanoscience, 2016

View PDFchevron_right

Molecular Modelling a Key Method for Potential Therapeutic Drug Discovery

Manish Tripathi

Biomedical Journal of Scientific & Technical Research, 2021

View PDFchevron_right

Insight parameter drug design for human beta-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of alpha-keto-[1,2,4]-oxadiazoles

Chau Ling Tham

View PDFchevron_right