Banking Umbilical Cord Blood (UCB) Stem Cells: Awareness, Attitude and Expectations of Potential Donors from One of the Largest Potential Repository (India) (original) (raw)
Related papers
Knowledge and attitudes among pregnant women and maternity staff about umbilical cord blood banking
Transfusion Medicine, 2016
Dear Sir, Umbilical cord blood (UCB) is a recognised and frequently used source of stem cells for allogeneic hematopoietic transplantation, not only for leukemias and lymphomas but also for bone marrow failure syndromes, haemoglobinopathies, immunodeficiencies and inborn errors of metabolism (Chen et al., 2013). Numerous studies have found the outcome after UCB transplantation to be as good as, or even better, than transplantation with stem cells from matched unrelated donors or siblings (Hwang et al., 2007), with similar leukaemia-free survival and leukaemia relapse (Chen et al., 2013), and lower incidence and severity of acute and chronic graft-versus-host disease (Rodrigues et al., 2014). However, UCB transplantation is more expensive than matched unrelated donor or sibling transplantation, because health care systems are obliged to compensate the cost of building up and managing UCB stem cell banks. UCB samples are collected from the remaining placental and UCB immediately after delivery and stored into either a public or private UCB bank. Despite substantial technical and scientific improvements in UCB banking and transplantation, the method has not yet reached its full potential to follow the growing demand for stem cells. This is partially caused by relatively small number of UCB samples fulfilling the high-quality standards required for storage in the Bone Marrow Donors Worldwide, mostly due to insufficient amount or quality of stem cells obtained from the umbilical cord. This can be improved, at least in part, by good training of staff assigned to collect UCB immediately after delivery. However, insufficient awareness of expectant parents about UCB banking in general (Palten & Dudenhausen, 2010) as well as insufficient knowledge regarding its usefulness may be another important cause of reluctance for donating UCB due to lack of motivation. In order to determine the awareness, level of knowledge, attitudes and information sources of pregnant women and hospital maternity staff about UCB banking and to explore a possible link concerning the knowledge about UCB banking between maternity staff members directly involved in perinatal care and pregnant women to whom they provide it, we conducted a prospective study in two university hospitals in Zagreb, Croatia, between November 2014 and April 2015. The study was granted approval by the Ethics Committees of both hospitals. Two simple anonymous questionnaires were used for pregnant women
Majmaah Journal of Health Sciences, 2015
The contemporary evidenced based medical care has improved the quality of life by timely detection, proven therapeutic regimens and preventive measures. Along with the advancement of health sciences, there is an unmet need for the communication of medicine and biomedical research. The goal of our journal is to advance knowledge while improving the effectiveness of health care delivery, raise the social awareness of important health care issues and the translation of knowledge. The current issue of the MJHS presents a blend of quality articles covering topics in health sciences. We take this opportunity to thank all of those who have contributed to the issue, and those clinician and researcher who, often on short notice, were kind enough to provide informed and valuable opinions on the submitted manuscripts. All the articles in this issue were thoroughly refereed, and we particularly thank the unnamed referees for their careful and timely job. We hope our readers enjoy reading this issue of Majmaah Journal of Health Sciences and we look forward to receiving and publishing more high-quality scientific manuscripts.
IJIRMPS, 2020
Background: As the new born is delivered and the umbilical cord divided, blood can be collected from the segment of cord, still attached to the placenta are known as “umbilical cord blood” stem cell. The blood collected in the umbilical cord is said to be a rich origin of stem. The blood contains stem cells which are also known as hematopoietic cells and these cells can convert into any types of organs in the body. These stem cells collected from the umbilical cord can heal genetic diseases related to blood and immune system like cancer, blood disorders and several life –threatening diseases. Objectives: Assess the level of knowledge regarding stem cells and cord blood banking among antenatal mothers. Find out the association between the level of knowledge regarding stem cells and cord blood banking among antenatal mothers with their selected demographic variables.
Pregnant women's knowledge and attitudes about stem cells and cord blood banking
International Nursing Review, 2009
This study was to determine pregnant women's knowledge and attitudes towards stem cells and cord blood banking in Istanbul, Turkey. Background: Stem cell research is one of the most important and, at the same time, the most controversial topics of science and technology today. Nurses need to understand stem cell research so they can enter the debate on this issue. They can become important sources of information in order to help parents understand the issues. Methods: This exploratory descriptive study was conducted in two antenatal outpatient clinics in Istanbul. The sample consisted of 334 pregnant women during routine prenatal visits. Data were collected in interviews by using an interview form developed by the researchers according to the literature. The form included demographic characteristics of participants and 20 questions about stem cells, storing cord blood and banking and 10 independent attitude statements. Results: The majority of the participants had a lack of knowledge about stem cells and cord blood banking and wanted more information. Before pregnancy, they received some information through the media (newspaper, Internet, television, etc.), but unintentionally. It was determined that they wanted information before becoming pregnant, more from their obstetrician but also from nurses and midwives. The majority also wanted to store their infants' cord blood and stated that they would be more likely to choose a public cord blood bank. Conclusion: Those giving ante-and perinatal care need to offer accurate and scientific counselling services on this subject to parents who need to be informed.
Knowledge, Awareness, and Attitudes toward Umbilical Cord Blood Biobanking
Open Access Macedonian Journal of Medical Sciences
BACKGROUND: Umbilical Cord Blood (UCB) stem cells are a non-invasive, effective alternative source of hematopoietic stem cells for the treatment of a variety of diseases. AIM: The aim of the study was to research knowledge, awareness, and attitudes of the general public and health professionals regarding the UCB storage. MATERIALS AND METHODS: A cross-sectional study was conducted with an online survey (n = 408) using the snowball method. RESULTS: A majority of respondents declared that they were not aware of UCB banking; however, people with an academic background in healthcare have a greater awareness of UCB banking. A subjective assessment found that their knowledge of UCB banking is better than that of non-professionals, however, they exhibited better knowledge and understanding of UCB use and banking in only a few aspects. People with an academic background in healthcare have a more polarized attitude toward cord blood banking and a higher percentage are unwilling to pay for UC...
Stem Cell Banking-Awareness and Acceptance by Expecting Mothers in Mumbai Region
International Journal of Business and Management, 2015
Stem cell technology is the breakthrough in Medical science. It seems to be the solution for all the human diseases and has the potential to change the way we live. Fatal diseases will cease to be fatal anymore with this innovation in medical science. Considering its promising endowment many countries have adopted Stem Cell Banking and Medical research and curative studies are growing in this area. This paper explores the pregnant women's awareness and acceptance of cord blood stem cells in Mumbai region. It is an empirical study to understand the association between the 'Awareness and Acceptance of Stem Cell Banking' and the demographic profile of the expecting mothers, the effect of the environmental factors such as Gynecologist initiative, promotional activities of Stem Cell Banks, cost associated with storage, and attitude towards preventive health care. Methodology adopted-Questionnaire was administered among the expecting mothers in Mumbai region and Bi-variate statistical analysis, cross tabulation, chi-square data analysis tool were adopted to understand the association among the variables defined. The authors have done a substantial literature review of recent news articles and papers publications to understand the stem cell technology and its benefits. This paper highlights future scope of research that can be carried out in this area with reference to practical application so that our Government can reap the benefits of this innovation in medical science for the citizens of our country.
Blood transfusion = Trasfusione del sangue, 2012
Umbilical cord blood (UCB) is a source of stem cells for allogeneic haematopoietic transplantation in paediatric and adult patients with haematological malignancies and other indications. Voluntary donation is the basis for the success of unrelated UCB transplantation programmes. In the last few years a growing number of private banks offer their services to expectant parents, to store UCB for future use. The debate concerning UCB donation and private preservation has been ongoing for several years. The aims of this single centre study were to explore knowledge about UCB stem cells and attitudes towards voluntary UCB donation or private UCB preservation among both blood donors and pregnant women. This study was conducted at the "Sapienza" University of Rome. Two types of anonymous questionnaires were prepared: one type was administered to 1,000 blood donors while the other type was distributed to 300 pregnant women. Most blood donors as well as the majority of pregnant wom...
Knowledge and Attitude of Staff Nurses on Umblical Cord Blood Stem Cell Banking
THE GENESIS
Umbilical cord blood (UCB) was once considered a waste product and was discarded with the placenta after delivery. With advances in medicine, it has been found to be a rich source of life-saving hematopoietic stem cells and has saved many lives in the recent decades. With advances in cord blood transplantation, many such patients are now able to find a fully or partially HLA-matched cord blood donor. The present study was exploratory descriptive in nature. A total of 170 staff nurses who met the inclusion criteria were selected from
Cell and Tissue Banking
The donation of umbilical cord blood (UCB) to public banks is essential to increase the probability of finding compatible donors for hematopoietic stem cell transplants. Brazil is currently the third-largest country in number of registered bone marrow donors, but it is far behind in terms of UCB donation. Thus, this questionnaire-based study aimed to assess Brazilian pregnant women's awareness, knowledge, beliefs, and opinions about UCB banking in order to identify the causes of low donation rates. Sixty-one percent of the responders were aware of UCB banking, but 86.9% of those declared to know little or very little about it. Only 14% of pregnant women were asked whether they would like to store or donate UCB. Just 13% have made a decision, and more than half decided not to donate or store it, with the leading cause being lack of knowledge. Finally, 94% of the responders believe that women should be told about UCB banking by their doctor before the last trimester of pregnancy. In conclusion, this study demonstrated that Brazilian pregnant women have insufficient knowledge about UCB banking, which affects their decision regarding UCB donation, and they wish to be better informed about it by health professionals.
Umbilical Cord Blood Banking: Consensus Statement of the Indian Academy of Pediatrics
Indian Pediatrics, 2018
Practitioners and people need information about the therapeutic potential of umbilical cord blood stem cells and pros and cons of storing cord blood in public versus private banks. Process: Indian Academy of Pediatrics conducted a consultative meeting on umbilical cord blood banking on 25th June 2016 in Pune, attended by experts in the field of hematopoietic stem cell transplantation working across India. Review of scientific literature was also performed. All expert committee members reviewed the final manuscript. Objective: To bring out consensus guidelines for umbilical cord banking in India. Recommendations: Umbilical cord blood stem cell transplantation has been used to cure many malignant disorders, hematological conditions, immune deficiency disorders and inherited metabolic disorders, even when it's partially HLA mismatched. Collection procedure is safe for mother and baby in an otherwise uncomplicated delivery. Public cord blood banking should be promoted over private banking. Private cord blood banking is highly recommended when an existing family member (sibling or biological parent) is suffering from diseases approved to be cured by allogenic stem cell transplantation. Otherwise, private cord blood banking is not a 'biological insurance', and should be discouraged. At present, autologous cord stem cells cannot be used for treating diseases of genetic origin, metabolic disorders and hematological cancers. Advertisements for private banking are often misleading. Legislative measures are required to regularize the marketing strategies of cord blood banking.