Six-year multicenter study on short-term peripheral venous catheters-related bloodstream infection rates in 204 intensive care units of 57 hospitals in 19 cities of India: International Nosocomial Infection Control Consortium (INICC) findings (original) (raw)
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Central venous catheter-related bloodstream infections in the intensivecare unit
2012
Context: Central venous catheter-related bloodstream infection (CRBSI) is associated with high rates of morbidity and mortality in critically ill patients. Aims: This study was conducted to determine the incidence of central venous catheter-related infections (CRIs) and to identify the factors influencing it. So far, there are very few studies that have been conducted on CRBSI in the intensive care unit in India. Settings and Design: This was a prospective, observational study carried out in the medical intensive care unit (MICU) over a period of 1 year from January to December 2004. Materials and Methods: A total of 54 patients with indwelling central venous catheters of age group between 20 and 75 years were included. The catheters were cultured using the standard semiquantitative culture (SQC) method. Statistical analysis used SPSS-10 version statistical software. Results: A total of 54 CVC catheters with 319 catheter days were included in this study. Of 54 patients with CVCs stu...
2020
Central Venous Catheters (CVCs) are indispensable in current intensive care treatment; also pose a greater risk of device related infections in comparison to any other type of medical device and are major cause of morbidity, mortality and increased expense. A cross sectional prospective study of one year duration was conducted in the tertiary care University Hospital ICU located in the rural region of Haryana, India, to determine the incidence of the central venous catheter related bloodstream infection (CRBSI), rate of catheter colonization and to identify the associated risk factors and the microbial spectrum of CRBSI along with the antimicrobial sensitivity pattern of microbial isolates. Sixty patients with central venous catheter inserted and admitted under ICU having signs and symptoms of septicaemia post 48 hours of central venous catheter insertion were included. The rate of CRBSI was assessed by paired quantitative blood culture method in the CVC and peripheral vein. The CRB...
Catheter related blood stream infections in ICU: A study from North India
International Journal of Infection Control, 2013
Central venous catheter (CVC) insertion is common in ICU practices; this can be a source of dangerous bacteremia, sepsis, multi organ failure and sometimes even death. We conducted this study to find out the rate of Catheter colonization, Catheter related blood stream infections (CRBSI), their association and microbial spectrum of CRBSI in critical care unit over 1 year period. Patients admitted in critical care units requiring central venous catheterization and presenting with signs of septicemia during catheterization period were investigated for catheter related blood stream infections. tip of Central venous catheter (CVC) as well as peripheral blood for culture were obtained simultaneously and processed according to pre determined protocol. Antimicrobial susceptibility testing was done for the isolated organisms. CRBSI rate of 10/1000 catheter days was observed, with Staphylococcus spp. as the most common organism. Since central venous catheters are increasingly being used in the critical care, regular surveillance for infections associated with them is essential.
Peripheral venous catheter related blood stream infection in intensive care unit
International Journal of Advances in Medicine, 2018
Intravenous catheters are indispensable in day-today medical practice, especially in intensive care unit. Catheter related bloodstream infection (CRBSI) is defined as the presence of bacteraemia originating from an intravenous catheter. 1 Although such catheters provide necessary vascular access, their use puts patients at risk for local and systemic infectious complications, including local site infection , catheter related blood stream infection, septic thrombophlebitis , endocarditis and other metastatic infections (e.g lung abscess brain abscess, osteomyelitis and endophthalmitis). 2 Among the intravenous catheters, peripheral venous catheters (PVC) are most widely used as its insertion does not require any special instrument or phlebotomist, beside that it is available at lowest level of health care facility. Due to the wide use of PVC in ICU and general wards, there is an ABSTRACT Background: Peripheral venous catheter related blood stream infections (PVC-BSI) are a common cause of morbidity and mortality in hospitals. Most of the catheter related blood stream infections occurs due to lack of proper aseptic measures. This study points out the risk factors microbial profile and antimicrobial susceptibility of isolates associated with PVC-BSI. The common organisms causing Catheter related BSI are Staphylococcus aureus (41.1%), and Klebsiella species (17.6%) followed by CONS and Enterococcus species. Objective of present study was to isolate and identify the organisms causing PCV-BSI, perform antimicrobial sensitivity testing of isolated organisms and to identify the associated risk factors and preventive measures that should be used. Methods: The study was conducted over a period of one year from August 2015 to July 2016 in the Department of Microbiology. Study group comprised of all the patients with peripheral venous catheterization who developed signs and symptoms of septicemia after 48 hrs of insertion of PVC. These patients were followed up from the time of catheterization till discharge. Peripheral venous catheter tip was collected under aseptic condition along with peripheral blood samples from a site other than the catheterized one. Samples were collected from patients at any point of time who developed signs and symptoms of septicemia after 48 hrs of catheter insertion. The length of time for which the PVC was in place was recorded. Results: In total, 87 cases were included in the study with mean catheter duration of 4.8 days accounting for 418 catheter days. Out of these 87 cases, 17 cases developed PVC-BSI (19.5%) and 34 cases developed colonization (24.1%). Staphylococcus species (41.1%) was the most common isolate. Conclusions: PVC-BSI has a significant role in hospital acquired infections and more studies are needed to establish this.
Journal of Hospital Infection, 2018
Background Vascular catheter-related bloodstream infections (CRBSIs) are highly preventable hospital-acquired infections and a major threat to patient safety. While there is significant information regarding CRBSI outcome among Intensive Care Unit (ICU) patients, data regarding non-ICU patients are scarce. Aim To determine the risk factors associated with 30-day mortality among non-ICU patients with nosocomial CRBSIs. Methods Prospective cohort study of non-ICU patients with nosocomial CRBSIs in a tertiary-care centre, between January 2004 and December 2014. Primary outcome: 30-day mortality, defined as death from any cause within 30 days of CRBSI. Follow-up: 30-days from CRBSI onset. Time until death was the dependent variable in Cox regression analysis. Findings A total of 546 cases of CRBSIs were identified; mean age: 64.5 years (IQR:55-75), male: 66%, and mean Charlson score: 3.59 (IQR:2-5). Of these, 58.4% resulted from central venous catheters and 41.6%, from peripheral venous catheters. The causative agents were Gram-positive cocci (70.1% of cases), Gram-negative bacilli (31.1%), and Candida species (1%). Mortality within 30 days was 13.9%, with no significant changes over the study period. Independent risk factors for 30-day mortality were
The Indian journal of chest diseases & allied sciences, 2022
Aims. To determine the incidence of central line associated bloodstream infections (CLABSIs) in the medical intensive care unit (ICU) and ward setting at All India Institute of Medical Sciences (AIIMS), New Delhi. Settings and Design. The study was conducted in the medical ICU, a 9-bedded ICU at the AIIMS, a tertiary care teaching hospital. The study design was a prospective observational study. Methods. One hundred patients admitted to medical ICU and the ward at AIIMS with an indwelling, non-tunnelled central venous catheter (CVC) in place at admission and those with a hospital stay with indwelling CVC for more than 48 hours were monitored. These patients were followed daily for the development of new onset sepsis 48 hours after insertion of CVC, in which case three sets of blood samples for culture were drawn over a span of 24 hours. Statistical Methods. Incidence of CLABSIs was measured per 1000 central line days. Results. One hundred patients hospitalised for an aggregate 1119 days acquired 29 hospital-acquired infections (HAIs), a rate of 38.8% or 31.2 HAIs per 1000 hospital days. The incidence of bloodstream infections (BSIs) in this group was 6.8%. No case of laboratory confirmed CLABSIs could be demonstrated. Incidence of clinical sepsis was 27.6% or 8.2 per 1000 CVC days. There were 9 cases out of the 29 patients (39.7%) who had evidence of HAIs with no apparent focus of infection. Only one of these cases had evidence of BSI with isolation of Staphylococcus aureus in both CVC tip culture and the simultaneous blood culture; however the antibiograms were different. Conclusions. The low rate of BSIs in the present study and the absence of occurrence of a laboratory confirmed CLABSI should be interpreted in the light of the small sample size of the study and the multitude of antibiotics received before the development of HAI.
2015
The catheter related blood stream infections (CRBSI) are identified as a threat of human kind worldwide affecting ICU admitted patients in hospitals. The rate of chances of getting the CRBSIs vary depending on the hospital set ups and several other variables. The aim of this study is to evaluate the percentage of bacterial colonisation and catheter related blood stream infections (CRBSI) together with the antibiotic susceptibility patterns in a tertiary care hospital located in Chennai, Tamilnadu. Of the 68 catheters studied out of 55 patients, the incidence of colonisation was found 37.6% and CRBSI was 14%. The pathogens identified from the cultures include S.aureus, Pneumonia sp. Klebisiella etc. Among this Staphylococcus aureus was found to be the major contributor of CRBSI with 25% rate of. With respect to antibacterial resistance 100% of Enterobacteriacae were ESBL producer, 49.0% Pseudomonas sp. were imipenem resistant, 65% Staphylococcus aureus were resistant to methicillin r...
CHEST Journal, 2005
Study objectives: To determine the risk of PICC-related BSI in hospitalized patients. Study design: Prospective cohort study using data from two randomized trials assessing the efficacy of chlorhexidine-impregnated sponge dressing and chlorhexidine for cutaneous antisepsis. Methods: PICCs inserted into the antecubital vein in two randomized trials during from 1998 to 2000 were prospectively studied; most patients were in an ICU. PICC-related BSI was confirmed in each case by demonstrating concordance between isolates colonizing the PICC at the time of removal and from blood cultures by restriction-fragment DNA subtyping. Results: Overall, 115 patients had 251 PICCs placed. Mean duration of catheterization was 11.3 days (total, 2,832 PICC-days); 42% of the patients were in an ICU at some time, 62% had urinary catheters, and 49% had received mechanical ventilation. Six PICC-related BSIs were identified (2.4%), four with coagulasenegative staphylococcus, one with Staphylococcus aureus, and one with Klebsiella pneumoniae, a rate of 2.1 per 1,000 catheter-days.