Multiple resistance mechanisms to azole antifungals in yeast clinical isolates (original) (raw)

Formation of Azole-Resistant Candida albicans by Mutation of Sterol 14-Demethylase P450

Osamu Gotoh

Antimicrobial Agents and Chemotherapy, 1999

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Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

Dominique Sanglard

Antimicrobial Agents and Chemotherapy, 1998

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Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14a-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

Dominique Sanglard

1998

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Contribution of mutations in the cytochrome P450 14alpha-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

Marcel Borgers, Hugo Vanden Bossche

Microbiology (Reading, England), 1999

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Vacuolar Sequestration of Azoles, a Novel Strategy of Azole Antifungal Resistance Conserved across Pathogenic and Nonpathogenic Yeast

Naseem Gaur

Antimicrobial Agents and Chemotherapy

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Cyclic AMP Signaling Pathway Modulates Susceptibility of Candida Species and Saccharomyces cerevisiae to Antifungal Azoles and Other Sterol Biosynthesis Inhibitors

Pooja Jain

Antimicrobial Agents and Chemotherapy, 2003

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Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

M. Weig

Antimicrobial Agents and Chemotherapy, 2010

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Copyright © 1997, American Society for Microbiology Molecular Biological Characterization of an Azole-Resistant

Hugo Vanden Bossche

1997

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Differential Azole Antifungal Efficacies Contrasted Using a Saccharomyces cerevisiae Strain Humanized for Sterol 14α-Demethylase at the Homologous Locus

Denis POMPON

Antimicrobial Agents and Chemotherapy, 2008

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Azole susceptibility and resistance in Candida dubliniensis

Derek Sullivan

Biochemical Society Transactions, 2005

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Candida tropicalis Antifungal Cross-Resistance Is Related to Different Azole Target (Erg11p) Modifications

Emilia Mellado

Antimicrobial Agents and Chemotherapy, 2013

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Molecular mechanisms of azole resistance in Candida bloodstream isolates

Andrea Kwa

BMC Infectious Diseases

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The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum

Aoyama Toshihiro

Journal of …, 2007

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Mechanisms of Azole Resistance in Clinical Isolates of Candida glabrata Collected during a Hospital Survey of Antifungal Resistance

Riccardo Torelli

Antimicrobial Agents and Chemotherapy, 2005

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Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms

Dominique Sanglard

Antimicrobial Agents and Chemotherapy, 2015

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Azole resistance in Candida albicans from animals: Highlights on efflux pump activity and gene overexpression

Jamille Sales

Mycoses, 2017

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Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature

Florent Morio

Diagnostic microbiology and infectious disease, 2010

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Genetic Dissection of Azole Resistance Mechanisms in Candida albicans and Their Validation in a Mouse Model of Disseminated Infection

Alix Coste

Antimicrobial Agents and Chemotherapy, 2010

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Azole Resistance by Loss of Function of the Sterol Δ 5,6 -Desaturase Gene ( ERG3 ) in Candida albicans Does Not Necessarily Decrease Virulence

Dominique Sanglard

Antimicrobial Agents and Chemotherapy, 2012

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Azole Resistance Reduces Susceptibility to the Tetrazole Antifungal VT-1161

Mikhail Keniya

Antimicrobial Agents and Chemotherapy

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The ergosterol biosynthesis pathway, transporter genes, and azole resistance in Aspergillus fumigatus

Gustavo Henrique

Medical Mycology, 2005

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Mechanisms of Azole Resistance in Petite Mutants of Candida glabrata

dominique CHABASSE

Antimicrobial Agents and Chemotherapy, 2004

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Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus

Sanjoy Paul

Antimicrobial agents and chemotherapy, 2017

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The ATP Binding Cassette Transporter Gene CgCDR1 from Candida glabrata Is Involved in the Resistance of Clinical Isolates to Azole Antifungal Agents

David Calabrese

1999

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Mechanisms of azole antifungal resistance in clinical isolates of Candida tropicalis

Shivaprakash M R

PLOS ONE, 2022

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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

Karl Kuchler

Antimicrobial Agents …, 1995

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Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B

M. Weig

Antimicrobial Agents and Chemotherapy, 2012

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Relative Contributions of the Candida albicans ABC Transporters Cdr1p and Cdr2p to Clinical Azole Resistance

sarah tsao

Antimicrobial Agents and Chemotherapy, 2009

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