Norovirus drug candidates that inhibit viral capsid attachment to human histo-blood group antigens (original) (raw)
Norovirus: Targets and tools in antiviral drug discovery
Dirk Jochmans
Biochemical Pharmacology, 2014
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Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance
Eloise Mastrangelo
Pharmaceuticals
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Computational studies on the interaction of ABO-active saccharides with the norovirus VA387 capsid protein can explain experimental binding data
Göran Larson, Per-Georg Nyholm
Journal of Computer-Aided Molecular Design, 2010
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An in silico virtual screening study for the design of norovirus inhibitors: fragment-based molecular docking and binding free energy calculations
Magnus Lundborg
Carbohydrate Research, 2013
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Identification of compelling inhibitors of human norovirus 3CL protease to combat gastroenteritis: A structure-based virtual screening and molecular dynamics study
Nawal Helmi
Frontiers in Chemistry
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Human Noroviruses' Fondness for Histo-Blood Group Antigens
Bishal Singh
Journal of Virology, 2014
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Atomic structure of the predominant GII.4 human norovirus capsid reveals novel stability and plasticity
Frederick Neill
Nature Communications
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Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease
Gerald Lushington
European journal of medicinal chemistry, 2018
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High-Resolution X-Ray Structure and Functional Analysis of the Murine Norovirus 1 Capsid Protein Protruding Domain
John Rubin
Journal of Virology, 2010
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Targeting Norovirus Infection—Multivalent Entry Inhibitor Design Based on NMR Experiments Dedicated to Professor Heinz Rüterjans on the occasion of his 75th birthday
Francisco Parra
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Unveiling of Pyrimidindinones as Potential Anti-Norovirus Agents—A Pharmacoinformatic-Based Approach
Oluwakemi Ebenezer
Molecules, 2022
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Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease
Gerald Lushington
Journal of Medicinal Chemistry, 2020
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Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors
Gerald Lushington
European Journal of Medicinal Chemistry, 2016
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Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease
Kurt Krause
Viruses
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In Silico Screening and Molecular Dynamics Simulation Studies in the Identification of Natural Compound Inhibitors Targeting the Human Norovirus RdRp Protein to Fight Gastroenteritis
Farah Anjum
International Journal of Molecular Sciences
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In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors
Jingxu Guo
Journal of Structural Biology: X, 2020
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Norovirus vaccines and potential antinorovirus drugs: recent advances and future perspectives
Lijuan Yuan
Future Virology, 2015
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GII.4 Human Norovirus: Surveying the Antigenic Landscape
Ralph Baric
Viruses
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Characterization of a novel conformational GII.4 norovirus epitope: Implications in norovirus-host interactions
Javier Buesa
Journal of Virology, 2016
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Targeting Norovirus Infection-Multivalent Entry Inhibitor Design Based on NMR Experiments
Julie Guiard
Chemistry - A European Journal, 2011
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More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules
David J Rowlands
Nature Structural & Molecular Biology, 2014
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Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle
Makoto Yamazaki
Journal of Virology, 2012
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The P Domain of Norovirus Capsid Protein Forms a Subviral Particle That Binds to Histo-Blood Group Antigen Receptors
Ming Tan
Journal of Virology, 2005
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Broadly cross-reactive human antibodies that inhibit genogroup I and II noroviruses
Gabriela Alvarado
Nature Communications, 2021
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Molecular Details of the Recognition of Blood Group Antigens by a Human Norovirus as Determined by STD NMR Spectroscopy
Francisco Parra
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Structure of human enterovirus 71 in complex with a capsid-binding inhibitor
Moh Yap
2013
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Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus
Mark Von Itzstein
Glycoconjugate Journal, 2006
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Noroviral P particle: Structure, function and applications in virus–host interaction
Intan Less
Virology, 2008
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Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
Naemi Welter
PLOS Biology
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Particle conformation regulates antibody access to a conserved GII.4 norovirus blockade epitope
Taylor Jones, Eric Donaldson
Journal of virology, 2014
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