Preparation of Silanized-Chitosan via Solution-Casting Method: Study on the Mechanical, Water Adsorption and Swelling Area Properties (original) (raw)
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Hystersis of Composites [Working Title]
Since long scientists explored natural/bio-polymers to explicit their innate features to develop certain novel utilities in modernization of prevalent Science & Technology. Consequently biotope derived polysaccharide embrace huge prospective desired functions. Amid, chitosan, the second most ubiquitous polymer after cellulose exists as a β-(1-4)-linked d-glucosamine/N-acetyl-d-glucosamine randomly distributed linear polycationic yield from partial deacetylation of chitin polysaccharide. Chitin's complexity limits its extraction/insolubility in aqueous solution, thus less studied/research until 1980s. As major polysaccharides are either neutral/negatively charged in an acidic environment, instead chitosan is cationic, eventually forms electrostatic complexes/multilayer structures/composites with anionic synthetic dopants/natural polymers. Chitosan own biocompatibility, non-toxicity, low allergy and biodegradability allow utility as in water treatment, wound-healing, pharmaceutical excipient/drug carrier, obesity treatment and scaffold for tissue engineering. It is reflected in the increasing number of related publications throughout in biomedical, environmental and industrials applications. Feeble chitosan solubility limits their applications, yet benign synthetic techniques viz.; sol-gel, encapsulation, chemical grafting are employed to yield composites/ hydrogels/films/granules which generates new functionality, besides enhanced biocompatibility and biodegradability. This chapter presents the R&D, trends and the latest prospects involved in advance synthesis of chitosan supported composites/ hydrogels/films/granules/sheets with special highlighted pharmaceutical/biomedical and environmental applications.
Chitosan and its Broad Applications: A Brief Review
Journal of Clinical and Experimental Investigations, 2021
Objective: This review summarizes the methods of chitosan production as well as its various potential applications. Materials and Methods: This study has been performed by literature review. Results: Chitin is a natural compound that is the second most abundant biological compound in nature. Chitin is found in many fungi species and aquatic crustaceans like crabs, shrimps, and many insects. Shrimp is the source of one of the most rapidly increasing businesses in the world. However, during shrimp processing, the hard exoskeleton of shrimps, like shrimp skin and head portions, is discarded as bio-waste. This exoskeleton of shrimp contains a considerable amount of chitin. Chitosan is a bio-product that is produced from chitin by the deacetylation process. Either chemical or biological processes can carry out the deacetylation process. The massive number of chitin treated as bio-waste can be used to produce chitosan. Chitosan is a biocompatible compound, naturally biodegradable, and non-toxic, and this compound can be used in various applications. Chitosan has potential antimicrobial and antioxidant activities. Moreover, it can also be used in drug delivery, biotechnology, bionanotechnology, food technology, regenerative medicine, medicine, numerous industrial applications, gene therapy, cancer therapy, agriculture, environmental protection, and so on. Conclusion: Chitosan can be used in almost all fields of biology. Although chitosan is not still used in all the mentioned fields shortly, chitosan should significantly impact these areas. More researches should be performed to make chitosan a compound of many applications and possibilities.