Parietal cell sensitivity to histamine in duodenal ulcer patients (original) (raw)

1994, European Journal of Gastroenterology & Hepatology

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Duodenal ulcer patients exhibit a greater skin response to histamine

Journal of the European Academy of Dermatology and Venereology, 1998

Background Histamine is considered a major mediator in the process of gastric acid secretion. When acid peptic activity overpowers the mucosal defense mechanism, peptic ulceration may develop. Is the hyperreactivity of patients with duodenal ulcer to histamine also expressed in the skin?

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