Identification of the Individual Residues That Determine Human CD59 Species Selective Activity
Stephen Tomlinson
Journal of Biological Chemistry, 1999
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Protection of erythrocytes from human complement-mediated lysis by membrane-targeted recombinant soluble CD59: a new approach to PNH therapy
Sean Gallagher
Blood, 2006
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Membrane defence against complement lysis: The structure and biological properties of CD59
Peter I Lachman
Immunologic Research, 1993
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Insights into the Human CD59 Complement Binding Interface Toward Engineering New Therapeutics
Stephen Tomlinson
Journal of Biological Chemistry, 2005
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Protection of human breast cancer cells from complement-mediated lysis by expression of heterologous CD59
Stephen Tomlinson
Clinical and Experimental Immunology, 1999
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Primary and Secondary CD59 Deficiency
Dror Mevorach
Encyclopedia of Medical Immunology
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Application of a novel inhibitor of human CD59 for the enhancement of complement-dependent cytolysis on cancer cells
Xuebin Qin
Cellular & molecular immunology, 2011
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Levels of expression of complement regulatory proteins CD46, CD55 and CD59 on resting and activated human peripheral blood leucocytes
Stephen E Christmas
Immunology, 2006
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Relative roles of decay-accelerating factor, membrane cofactor protein, and CD59 in the protection of human endothelial cells against complement-mediated lysis
Mohamed Daha
European Journal of Immunology, 1992
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Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex
Stephen Tomlinson
Acta Crystallographica Section D Biological Crystallography, 2007
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Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b
A. Shahsafaei
Mammalian Genome, 2001
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A High-Affinity Inhibitor of Human CD59 Enhances Complement-Mediated Virolysis of HIV-1: Implications for Treatment of HIV-1/AIDS
Bruce Shiramizu
The Journal of Immunology, 2010
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Mapping the Active Site of CD59
Stephen Tomlinson
Journal of Experimental Medicine, 1997
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CD59 incorporation protects hepatitis C virus against complement-mediated destruction
Xuebin Qin
Hepatology, 2011
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Soluble CD59-ANTIGEN Levels Are Increased in Renal Disease Plasma
Oluseyi Vanderpuye
American Journal of Biochemistry and Biotechnology, 2013
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CD59 protects rat kidney from complement mediated injury in collaboration with Crry
Hidechika Okada
Kidney International, 2000
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Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria
Annie Bygrave
Blood, 2001
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Control of C3b and C5b deposition by CD46 (membrane cofactor protein) after alternative but not classical complement activation
Patricia Devaux
European Journal of Immunology, 1999
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The membrane complement regulatory protein CD59 and its association with rheumatoid arthritis and systemic lupus erythematosus
Monika Gandhi
Current Medicine Research and Practice, 2019
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Analysis of human CD59 tissue expression directed by the CMV-IE-1 promoter in transgenic rats
Ignacio Anegon
Transgenic Research, 1996
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Immunoadsorbent affinity purification of the fifth component (C5) of human complement and development of a highly sensitive hemolytic assay
Marjorie Jones
Journal of Immunological Methods, 1980
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Targeting of functional antibody-CD59 fusion proteins to a cell surface
Stephen Tomlinson
Journal of Clinical Investigation, 1999
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Regulation of CD59 expression on the human endothelial cell line EA.hy 926
Pirkko Mattila
European Journal of Immunology, 1993
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Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis
Timo Lehto
The Biochemical journal, 1996
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Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein
Russel Kaufman
Proceedings of the National Academy of Sciences of the United States of America, 1992
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Molecular pathogenesis of human CD59 deficiency
Dror Mevorach
Neurology Genetics
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Complement regulation in the rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells
Richard Quigg
Kidney International, 1995
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Regulation of complement functional efficiency by histidine-rich glycoprotein
Nan-Shan Chang
…, 1992
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Human CD59 expressed in transgenic mouse hearts inhibits the activation of complement
HERMAN WALDMANN
Transplant Immunology, 1995
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Complement Regulator CD59 Protects Against Atherosclerosis by Restricting the Formation of Complement Membrane Attack Complex
A. Shahsafaei
Circulation Research, 2009
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Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases
Yuki Iwayanagi
Scientific reports, 2017
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High level transcription of the complement regulatory protein CD59 requires an enhancer located in …
Yukiko Tone
Journal of Biological Chemistry, 1999
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CD46: expanding beyond complement regulation
Darcy Gill
Trends in Immunology, 2004
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The expression of CD59 in normal human nervous tissue
S. Mørk
Immunology, 1994
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Immunohistological analysis of CD59 and membrane attack complex of complement in muscle in juvenile dermatomyositis
Suely Marie
2002
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