Hypermethylation of p15 Gene in Diffuse - Large B-Cell Lymphoma: Association with Less Aggressiveness of the Disease (original) (raw)
2014, Clinical and Translational Science
AI-generated Abstract
This study investigates the hypermethylation of the p15 gene in diffuse large B-cell lymphoma (DLBCL) and its association with disease aggressiveness. Through the analysis of biopsy samples, a significant correlation was found between p15 gene hypermethylation and a less aggressive form of DLBCL, suggesting that hypermethylation may serve as a potential biomarker for predicting disease outcomes. The findings highlight the importance of epigenetic modifications in the behavior of DLBCL and propose new avenues for therapeutic exploration, including the targeting of methylation pathways.
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