Integrons and Transposons on the Salmonella enterica Serovar Typhimurium Virulence Plasmid (original) (raw)

2005, Antimicrobial Agents and Chemotherapy

AI-generated Abstract

Antibiotic resistance is formally an adaptive mechanism contributing to bacterial virulence. In Salmonella enterica serotypes, several virulence genes have been located on plasmids. This report describes the molecular characterization of a Salmonella virulence plasmid from the ST4 strain isolated in Italy in 1997, which showed resistance to multiple antibiotics and contained two class 1 integrons carrying resistance genes. Additionally, findings suggest that virulence plasmids may evolve through the acquisition of resistance genes that often colocalize to form resistance islands, potentially through recombination and transposition processes.

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