Cytomorphology of Chondroid Syringoma: Analysis of 20 Cases and Review of Literature (original) (raw)

Chondroid syringoma: Cytomorphology of four cases and review of literature

2016

Introduction: Chondroid syringoma also known as benign mixed tumor of the skin presents as a slow growing, painless dermal/subcutaneous nodule. The cytological features of this entity have been rarely described, and are limited to a few case reports. The present study emphasizes on the cytological features of chondroid syringoma on fine needle aspiration (FNA). Materials and Methods: A retrospective analysis of all cases of chondroid syringoma diagnosed/missed on fine needle aspiration (FNA) with subsequent histopathologic confirmation over a period of five years (2011-2015) was undertaken. FNA was done using a 23 gauge needle fitted to a 10 mL syringe mounted on Franzen’s handle. Chondroid syringoma was diagnosed on cytology in 3 cases of which 2 were confined to head and neck region while 1 was in axilla. One case was misdiagnosed as fibroadenoma with secondary myxoid change on cytology. Results: Case 1 was a 57-year-old man with a nodule in left axilla. Case 2 was a 52-year-old w...

A Case Report of Chondroid Syringoma - A Rare Adnexal Tumor at Rare Site

Annals of International medical and Dental Research

Chondroid syringoma is skin adnexal tumor. It is a rare tumor, which can be benign as well as malignant. It is composed of epithelial and stromal components; therefore, known as mixed tumor. Clinically it presents as painless subcutaneous nodule, usually in head and neck region. Histopathology is the only mode of diagnosis. But it can't reliably differentiate benign or malignant tumor. So regular follow up after excision is needed. We present a case of young female with swelling left little finger, which was clinically diagnosed as neuroma, but histopathology suggested the diagnosis of chondroid syringoma. This case is being presented for its rarity and rare location.

Chondroid Syringoma: A case with unusual localization

Chondroid syringoma is a skin tumour with benign character that is named as mixcutaneous tumour. Chondroid sy-ringoma grows slowly without pain and ulcer and is seen as subcutaneous or intracutaneous in 0.5-3 cm size. Chondroid syringoma is generally seen in middle age and old men in head and neck region. It can rarely trunk, back, extremities and genital organs. Since chondroid syringoma is a benign lesion, it was reported in malign and atypic forms. The most important clinical finding of malign tumours is a rapid growing bulk. Malign chondroid syringoma is generally seen in young female patients in body and extremity localizations. Because of malign transformation, potential, total excision is the preferred treatment in benign chondroid syringomas. Despite being rare lesions, in subcutaneous nodules in body and extremities, particularly in head and neck region, chondroid syringoma should be thought. In this study, benign a case chondroid syringoma locating in extremity of young female patient was presented

Giant chondroid syringoma with divergent differentiation: Cyto-histo-immuno correlation

International Journal of Applied and Basic Medical Research, 2013

Chondroid syringoma is a rare benign skin adnexal tumor of eccrine/apocrine origin affecting commonly the head and neck region. It is also called as mixed tumor of skin because of the presence of both the epithelial and mesenchymal components. There are very few case reports of chondroid syringoma diagnosed on fine needle aspiration cytology (FNAC). We hereby report a case of giant chondroid syringoma occurring over the lower back in a 50-year-old male, diagnosed initially on cytology and confirmed by histopathology. This case is reported for its unusual size and site of occurrence. We describe the clinical features, cytology, histopathology, immunohistochemistry, and differential diagnosis of giant chondroid syringoma along with review of literature.

Case of chondroid syringoma mimicking as nodular hidradenoma: A diagnostic pitfall on cytopathology

Diagnostic cytopathology, 2017

Limited literature is available on the use of fine needle aspiration (FNA) for skin tumors. Awareness of cytological features of these lesions is important to prevent misdiagnosis. A 45-year-old male, presented with slowly growing swelling over the thigh since 4 years. FNA from multiple sites yielded highly cellular smears with a dual cell population consisting of cells with small round nucleus scanty cytoplasm and polygonal cells with moderate to abundant cytoplasm. Extracellular basement membrane like material was also noted. A diagnosis of benign adnexal neoplasm, suggestive of nodular hidradenoma was made. Paraffin sections showed an encapsulated dermal tumor composed of ductal and myoepithelial cells in ducts, sheets, strands with chondromyxoid stroma. A final diagnosis of chondroid syringoma was given following evaluation of histopathology slides and Immunohistochemistry. FNA interpretation of skin tumors can be challenging since literature is limited. The placement of tumors ...

Chondroid Syringoma: An Uncommon Adnexal Tumor at an Unusual Site

Acta Scientific Cancer Biology

Chondroid syringoma is also known as mixed tumor of skin due to its resemblance with mixed salivary gland tumor. It was first described by Billroth. It is a biphasic tumor composed of proliferation of epithelial and mesenchymal components. Predominantly seen in middle aged males in head and neck region. Our case report is of a young female who presented with a nodular firm swelling on the back.

Benign chondroid syringoma: a confusing clinical diagnosis

European Journal of Plastic Surgery, 2002

Benign chondroid syringomas are benign adnexal tumors that occur most commonly in the head and neck region. There are two histological types of chondroid syringoma. They usually present as firm intradermal or subcutaneous nodules. Clinically these tumors are frequently misdiagnosed. The differential diagnosis is epidermal cyst, lipoma, and pilar cyst. We present the benign chondroid syringomas seen during the period of August 1995 to August 2001. There were 13 chondroid syringomas in 1921 skin lesions (1.07%).

Malignant Chondroid Syringoma in a West African Cancer Institute: A Case Report

International Journal of Surgery Case Reports, 2016

To report a case of malignant chondroid syringoma, a rare skin tumor at Joliot Curie Cancer Institute in Dakar. RESULTS: We report a case of malignant chondroid syringoma of the deltoid and axilla in a 53 year old patient. Malignant chondroid syringoma is an extremely rare tumor of the sweat glands. It is included in myoepithelial tumors of the skin. It has an epithelial component with eccrin or apocrin differentiation, and myoepithelial component. It preferentially seat at the extremities. We report an unusual case with deltoid presentation and axillary mass masqueriding as metastatic lymph node. Surgery is the main treatment. It has a poor prognosis.

Benign Chondroid Syringoma on Chin: A Case Report and Literature Review

Cureus

Chondroid syringoma is a cutaneous adnexal tumor originating from sweat glands origin. It is rare in occurrence and usually benign, having an incidence of 0.01 to 0.098%. As these tumors are uncommon, their diagnosis is missed many times and are misdiagnosed. Hence in any case of facial skin swelling increasing slowly in size, this entity should be kept in mind as one of the possibilities and differential diagnosis. Histopathological examination of the excision biopsy gives the definitive confirmatory diagnosis. Surgically excising the swelling locally along with a surrounding normal tissue cuff is the standard treatment given which prevents recurrence. Hereby we present a 35-year-old case of facial chondroid syringoma having a focal component of eccrine hidrocystoma, keratinous cyst as well as syringocystadenoma papilliferum on the chin that was clinically suspected to be an epidermoid cyst or mucocele.