Ventilation control for airborne transmission of human exhaled bio-aerosols in buildings (original) (raw)
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Advances in preventive medicine, 2011
Health care facility ventilation design greatly affects disease transmission by aerosols. The desire to control infection in hospitals and at the same time to reduce their carbon footprint motivates the use of unconventional solutions for building design and associated control measures. This paper considers indoor sources and types of infectious aerosols, and pathogen viability and infectivity behaviors in response to environmental conditions. Aerosol dispersion, heat and mass transfer, deposition in the respiratory tract, and infection mechanisms are discussed, with an emphasis on experimental and modeling approaches. Key building design parameters are described that include types of ventilation systems (mixing, displacement, natural and hybrid), air exchange rate, temperature and relative humidity, air flow distribution structure, occupancy, engineered disinfection of air (filtration and UV radiation), and architectural programming (source and activity management) for health care ...
Annals of Occupational Hygiene, 2015
Most studies on the transmission of infectious airborne disease have focused on patient room air changes per hour (ACH) and how ACH provides pathogen dilution and removal. The logical but mostly unproven premise is that greater air change rates reduce the concentration of infectious particles and thus, the probability of airborne disease transmission. Recently, a growing body of research suggests pathways between pathogenic source (patient) and control (exhaust) may be the dominant environmental factor. While increases in airborne disease transmission have been associated with ventilation rates below 2 ACH, comparatively less data are available to quantify the benefits of higher air change rates in clinical spaces. As a result, a series of tests were conducted in an actual hospital to observe the containment and removal of respirable aerosols (0.5-10 μm) with respect to ventilation rate and directional airflow in a general patient room, and, an airborne infectious isolation room. Higher ventilation rates were not found to be proportionately effective in reducing aerosol concentrations. Specifically, increasing mechanical ventilation from 2.5 to 5.5 ACH reduced aerosol concentrations only 30% on average. However, particle concentrations were more than 40% higher in pathways between the source and exhaust as was the suspension and migration of larger particles (3-10 μm) throughout the patient room(s). Computational analyses were used to validate the experimental results, and, to further quantify the effect of ventilation rate on exhaust and deposition removal in patient rooms as well as other particle transport phenomena.
Control of airborne infectious disease in buildings: Evidence and research priorities
Indoor Air, 2021
The evolution of SARS-CoV-2 virus has resulted in variants likely to be more readily transmitted through respiratory aerosols, underscoring the increased potential for indoor environmental controls to mitigate risk. Use of tight-fitting face masks to trap infectious aerosol in exhaled breath and reduce inhalation exposure to contaminated air is of critical importance for disease control. Administrative controls including the regulation of occupancy and interpersonal spacing are also important, while presenting social and economic challenges. Indoor engineering controls including ventilation, exhaust, air flow control, filtration, and disinfection by germicidal ultraviolet irradiation can reduce reliance on stringent occupancy restrictions. However, the effects of controls-individually and in combination-on reducing infectious aerosol transfer indoors remain to be clearly characterized to the extent needed to support widespread implementation by building operators. We review aerobiologic and epidemiologic evidence of indoor environmental controls against transmission and present a quantitative aerosol transfer scenario illustrating relative differences in exposure at close-interactive, room, and building scales. We identify an overarching need for investment to implement building controls and evaluate their effectiveness on infection in well-characterized and real-world settings, supported by specific, methodological advances. Improved understanding of engineering control effectiveness guides implementation at scale while considering occupant comfort, operational challenges, and energy costs. Practical Implications Emerging variants of SARS-CoV-2 have led to increased infectivity by the aerosol inhalation mode and increasing infection incidence. Even in the absence of symptoms, people infected with respiratory viruses can exhale infectious aerosols that can be inhaled, deposit in the respiratory tract, and initiate infection. Indoor environments are the predominant settings for respiratory infection transmission because people spend most of their time indoors, and because concentrations of infectious aerosols can accumulate, resulting in hazardous inhalation exposure at close-interactive, room (even at distances much greater than two meters), and building scales. We illustrate the relative respiratory aerosol transfer and exposure at these scales, provide an overview of the scientific basis of engineering controls that can be deployed in buildings to reduce transfer between people, and outline priority research directions to guide widespread implementation of controls in buildings.
Removal of airborne contamination in airborne infectious isolation rooms
Ashrae Journal, 2019
The study discussed in this article evaluated the ventilation performance of three strategies for HVAC control for airborne infectious diseases induced by contaminated exhaled air from patients in an airborne infectious isolation room (AIIR). This article examines airflow path and airborne pollutant distribution by computational fluid dynamics modeling and field measurement. In hospitals, the risk of airborne virus diffusion mainly depends on airflow behavior and changes in direction caused by supply air and exhaust air locations. An improved isolation room ventilation strategy has been developed, and is found to be the most efficient in removing contaminants based on observations and simulation results from three ventilation systems.
Experimental and Computational Multiphase Flow
This study numerically investigated the transport characteristics of the cough-expelled droplets and their corresponding exposure risk of each occupant under various mixing ventilation layouts. Transient simulations were conducted in a conference room, while pathogen-bearing droplets were released by a standing speaker. The results showed that droplet residues (< 40 μm) had a high potential to reach occupant's breathing zone, among which the number fraction of aerosol residues (< 10 μm) could be nearly doubled compared with that of the rest droplet residues in the breathing zone. Occupants' exposure risks were found very sensitive to the ventilation layouts. The strong ventilated flow could significantly promote droplet dispersions when those inlets were closely located to the infectious speaker, resulting in all occupants exposed to a considerable fraction of aerosols and droplets within a given exposure time of 300 s. The mixing ventilation layout did not have a consistent performance on restricting the pathogen spread and controlling the occupant's exposure risk in an enclosed workspace. Its performance could be highly sensitive to the location of the infectious agent. Centralized vent layouts could provide relatively more consistent performance on removing droplets, whilst some local airflow recirculation with locked droplets were noticed.
Transactions of the Indian National Academy of Engineering
With the outbreak of pandemic COVID-19, protection of public and health workers has become a national priority. In this regard, it is desirable to study the coughing-and sneezing-generated pathogen aerosols, its dispersion and transportation in isolation rooms, clinics, confined spaces and other general public places to evolve efficient ventilation system along with suitable protective measures to limit the spread of the virus. The present paper describes the overall experimental scheme supported with computational fluid dynamics evaluation to address this problem for evolution of optimal ventilation system using the National Aerosol Facility at IIT Kanpur set up in collaboration with BARC Trombay. The outcome of this study is aimed to evolve a national standard for optimum isolation rooms that would provide adequate protection to health workers.
ASHRAE transactions, 2016
Exposure to airborne influenza (or flu) from a patient's cough and exhaled air causes potential flu virus transmission to the persons located nearby. Hospital-acquired influenza is a major airborne disease that occurs to health care workers (HCW). This paper examines the airflow patterns and influenza-infected cough aerosol transport behavior in a ceiling-ventilated mock airborne infection isolation room (AIIR) and its effectiveness in mitigating HCW's exposure to airborne infection. The computational fluid dynamics (CFD) analysis of the airflow patterns and the flu virus dispersal behavior in a mock AIIR is conducted using the room geometries and layout (room dimensions, bathroom dimensions and details, placement of vents and furniture), ventilation parameters (flow rates at the inlet and outlet vents, diffuser design, thermal sources, etc.), and pressurization corresponding to that of a traditional ceiling-mounted ventilation arrangement observed in existing hospitals. The...
Assessment of displacement ventilation systems in airborne infection risk in hospital rooms
PLOS ONE
Efficient ventilation in hospital airborne isolation rooms is important vis-à-vis decreasing the risk of cross infection and reducing energy consumption. This paper analyses the suitability of using a displacement ventilation strategy in airborne infection isolation rooms, focusing on health care worker exposure to pathogens exhaled by infected patients. The analysis is mainly based on numerical simulation results obtained with the support of a 3-D transient numerical model validated using experimental data. A thermal breathing manikin lying on a bed represents the source patient and another thermal breathing manikin represents the exposed individual standing beside the bed and facing the patient. A radiant wall represents an external wall exposed to solar radiation. The air change efficiency index and contaminant removal effectiveness indices and inhalation by the health care worker of contaminants exhaled by the patient are considered in a typical airborne infection isolation room set up with three air renewal rates (6 h -1 , 9 h -1 and 12 h -1 ), two exhaust opening positions and two health care worker positions. Results show that the radiant wall significantly affects the air flow pattern and contaminant dispersion. The lockup phenomenon occurs at the inhalation height of the standing manikin. Displacement ventilation renews the air of the airborne isolation room and eliminates the exhaled pollutants efficiently, but is at a disadvantage compared to other ventilation strategies when the risk of exposure is taken into account.
Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 2022
COVID-19 is a severe and rapidly spreading respiratory disease that can be transmitted through airborne particles, emitted from cough. This study investigated the influence of underfloor air distribution (UFAD) and overhead air distribution on the diffusion of the coughed particles emitted from two infected patients in an isolation ward. Additionally, the study examined the performance of mounting retractable covers around the exhausts on minimizing the dispersion of the particles. A coupled Eulerian-Lagrangian approach is adopted by using a discrete random walk model. The effect of Brownian force, drag force with Cunningham slip correction factor, turbulence dispersion, Rosin-Rammler, and the breakup is considered in the respiratory airborne coughed particles simulation. The model has a good agreement with the experimental data. The results show that overhead air distribution (case 1) disperses the particles faster to the occupied zone due to the strong mixing between downward inlet airflow and indoor air accompanied by infectious particles. The usage of retractable covers (case 2) significantly minimized the diffusion of the particles inside the ward and their residence time. The particles quantity drops by 53, 98.62, and 99.94 % at 2.0, 10.0, and 120.0 s, respectively, compared to case 1. Case 2 shows the best efficient protection and inhaled air quality for the HCW in all the walking areas inside the room. The upward inlet air in underfloor air distribution (case 3) keeps particles floating for a while at a higher level near the ceiling exhausts, enhancing removal efficiency. Also, it has a slower lateral dispersion of the particles than in case 1. Underfloor air distribution minimized the number of particles by 30.0 % at 120.0 s, compared to overhead air distribution. Inlet air location significantly affects the diffusion of infectious particles in the indoor environment.