Lung Cancer and Paraneoplastic Neurologic Syndromes. Case Report and Review of the Literature (original) (raw)

Paraneoplastic neurologic syndromes (PNSs) are rare clinical manifestations associated with cancer, particularly small-cell lung cancer. This case report details a 77-year-old man with significant distal polyneuropathy linked to the presence of anti-myelin-associated glycoprotein (MAG) antibodies and highlights the immune response involved in PNSs. The paper discusses the pathophysiological mechanisms of such syndromes in lung cancer, emphasizing their diagnostic significance and the necessity for early cancer screening in cases of anti-MAG neuropathy.