NATURE MEDICINE ADVANCE ONLINE PUBLICATION GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease (original) (raw)

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

Neil Kowall

Nature medicine, 2014

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Recent progress on the role of GABAergic neurotransmission in the pathogenesis of Alzheimer’s disease

Nurul Kabir

Reviews in The Neurosciences, 2016

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Reduction in the neuronal surface of post‐ and pre‐synaptic GABA B receptors in the hippocampus in a mouse model of Alzheimer´s disease

José Martínez-Hernández

Brain Pathology

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Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model

Isabelle Aubert, Maria Davoli

Journal of Alzheimer's disease : JAD, 2012

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Alzheimer’s Disease Enhanced Tonic Inhibition is Correlated With Upregulated Astrocyte GABA Transporter-3/4 in a Knock-In APP Mouse Model

Afia Ali

Frontiers in Pharmacology

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GABAA receptor β2 and β3 subunits mRNA in the hippocampal formation of aged human brain with Alzheimer-related neuropathology

Dennis Grayson

Molecular Brain Research, 1998

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GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer’s disease

J. Yajeya

Frontiers in Cellular Neuroscience, 2014

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Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission

Philippe Gailly

Scientific Reports

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Selective modulation of α5 GABAA receptors exacerbates aberrant inhibition at key hippocampal neuronal circuits in APP mouse model of Alzheimer’s disease

Afia Ali

2020

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Density of GABAB Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease

José Martínez-Hernández

International Journal of Molecular Sciences

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Production of GABA by cultured hippocampal glial cells

Tom Novak

Neurochemistry International, 2004

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GABA A receptors in aging and Alzheimer’s disease

Robert Rissman

Journal of Neurochemistry, 2007

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Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances

Tomas Ondrejcak

Pharmacology Biochemistry and Behavior

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The amount of astrocytic GABA positively correlates with the degree of tonic inhibition in hippocampal CA1 and cerebellum

Taekeun Kim

2011

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Activated astrocytes: a therapeutic target in Alzheimer’s disease?

Stacey Fuller

Expert Review of Neurotherapeutics, 2009

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GABAA agonist muscimol ameliorates learning/memory deficits in streptozocin-induced Alzheimer’s disease non-transgenic rat model

Ulrika Beitnere

SpringerPlus, 2015

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Glutamate and GABA in Microglia-Neuron Cross-Talk in Alzheimer’s Disease

Joanna B Strosznajder

International Journal of Molecular Sciences, 2021

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Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology

yuya sakimoto

International Journal of Molecular Sciences, 2021

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Defective Tumor Necrosis Factor- -dependent Control of Astrocyte Glutamate Release in a Transgenic Mouse Model of Alzheimer Disease

Chiara Valori

Journal of Biological Chemistry, 2005

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Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons

Steffen Hartel

Antioxidants

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Etazolate, a neuroprotective drug linking GABAAreceptor pharmacology to amyloid precursor protein processing

Fabien Schweighoffer

Journal of Neurochemistry, 2008

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Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

Jeffrey Savas

Science, 2019

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Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3

Rosemarie Grantyn

Frontiers in Neural Circuits, 2013

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Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus

Simo Oja

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1997

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Alterations on Na+,K+-ATPase and Acetylcholinesterase Activities Induced by Amyloid-β Peptide in Rat Brain and GM1 Ganglioside Neuroprotective Action

Vera Maria Treis Trindade

Neurochemical Research, 2013

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Grolla AA, Fakhfouri G, Balzaretti G, Marcello E, Gardoni F, Canonico P,Diluca M, Genazzani AA, Lim D. Aβ leads to Ca(2+) signaling alterations andtranscriptional changes in glial cells. Neurobiol Aging. 2012 Jun 4

Gohar Fakhfouri

Neurobiology of Aging

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Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer′s disease progression?

Anna Chiarini, Ilaria Dal Prà, Ubaldo Armato

Neural Regeneration Research, 2015

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