NATURE MEDICINE ADVANCE ONLINE PUBLICATION GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease (original) (raw)
GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease
Neil Kowall
Nature medicine, 2014
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Recent progress on the role of GABAergic neurotransmission in the pathogenesis of Alzheimer’s disease
Nurul Kabir
Reviews in The Neurosciences, 2016
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Reduction in the neuronal surface of post‐ and pre‐synaptic GABA B receptors in the hippocampus in a mouse model of Alzheimer´s disease
José Martínez-Hernández
Brain Pathology
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Hippocampal GABAergic neurons are susceptible to amyloid-β toxicity in vitro and are decreased in number in the Alzheimer's disease TgCRND8 mouse model
Isabelle Aubert, Maria Davoli
Journal of Alzheimer's disease : JAD, 2012
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Alzheimer’s Disease Enhanced Tonic Inhibition is Correlated With Upregulated Astrocyte GABA Transporter-3/4 in a Knock-In APP Mouse Model
Afia Ali
Frontiers in Pharmacology
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GABAA receptor β2 and β3 subunits mRNA in the hippocampal formation of aged human brain with Alzheimer-related neuropathology
Dennis Grayson
Molecular Brain Research, 1998
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GABAergic neurotransmission and new strategies of neuromodulation to compensate synaptic dysfunction in early stages of Alzheimer’s disease
J. Yajeya
Frontiers in Cellular Neuroscience, 2014
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Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission
Philippe Gailly
Scientific Reports
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Selective modulation of α5 GABAA receptors exacerbates aberrant inhibition at key hippocampal neuronal circuits in APP mouse model of Alzheimer’s disease
Afia Ali
2020
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Density of GABAB Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease
José Martínez-Hernández
International Journal of Molecular Sciences
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Production of GABA by cultured hippocampal glial cells
Tom Novak
Neurochemistry International, 2004
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GABA A receptors in aging and Alzheimer’s disease
Robert Rissman
Journal of Neurochemistry, 2007
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Glutamate receptors in preclinical research on Alzheimer's disease: Update on recent advances
Tomas Ondrejcak
Pharmacology Biochemistry and Behavior
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The amount of astrocytic GABA positively correlates with the degree of tonic inhibition in hippocampal CA1 and cerebellum
Taekeun Kim
2011
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Activated astrocytes: a therapeutic target in Alzheimer’s disease?
Stacey Fuller
Expert Review of Neurotherapeutics, 2009
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GABAA agonist muscimol ameliorates learning/memory deficits in streptozocin-induced Alzheimer’s disease non-transgenic rat model
Ulrika Beitnere
SpringerPlus, 2015
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Glutamate and GABA in Microglia-Neuron Cross-Talk in Alzheimer’s Disease
Joanna B Strosznajder
International Journal of Molecular Sciences, 2021
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Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology
yuya sakimoto
International Journal of Molecular Sciences, 2021
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Defective Tumor Necrosis Factor- -dependent Control of Astrocyte Glutamate Release in a Transgenic Mouse Model of Alzheimer Disease
Chiara Valori
Journal of Biological Chemistry, 2005
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Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons
Steffen Hartel
Antioxidants
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Etazolate, a neuroprotective drug linking GABAAreceptor pharmacology to amyloid precursor protein processing
Fabien Schweighoffer
Journal of Neurochemistry, 2008
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Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission
Jeffrey Savas
Science, 2019
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Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3
Rosemarie Grantyn
Frontiers in Neural Circuits, 2013
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Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus
Simo Oja
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1997
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Alterations on Na+,K+-ATPase and Acetylcholinesterase Activities Induced by Amyloid-β Peptide in Rat Brain and GM1 Ganglioside Neuroprotective Action
Vera Maria Treis Trindade
Neurochemical Research, 2013
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Grolla AA, Fakhfouri G, Balzaretti G, Marcello E, Gardoni F, Canonico P,Diluca M, Genazzani AA, Lim D. Aβ leads to Ca(2+) signaling alterations andtranscriptional changes in glial cells. Neurobiol Aging. 2012 Jun 4
Gohar Fakhfouri
Neurobiology of Aging
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Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer′s disease progression?
Anna Chiarini, Ilaria Dal Prà, Ubaldo Armato
Neural Regeneration Research, 2015
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