[Malignant priapism and secondary bladder cancer] (original) (raw)
Related papers
Penile Metastatic Disease Presenting as Malignant Priapism: A Case Report
Journal of Urological Surgery
Penile metastatic disease is an uncommon condition with a dismal prognosis. Reported herein is a case of metachronous penile metastasis from bladder urothelial carcinoma, which presents as malignant priapism without tumoral masses. The authors explain the imaging and pathologic findings that led to its diagnosis and staging.
Cureus
Priapism is one of the most common urologic emergencies and is characterized by a prolonged and painful erectile state unrelated to sexual stimulation or sexual desire. Neoplasm-associated priapism is a rare condition and is usually caused by corporeal metastases of other pelvic area malignancies. Primary penile malignancy-related malignant priapism is extremely rare. In this reported case, an 82-year-old male presented with priapism. The penile doppler ultrasound and pelvic magnetic resonance imaging were compatible with ischemic priapism and corporal mass. Subsequently, the patient underwent total penectomy and bilateral superficial inguinal lymphadenectomy. The pathology report was consistent with primary penile squamous cell cancer (SCC), so the patient underwent adjuvant radiotherapy. However, he developed multiple metastases and could survive for about six months. The patient had undergone radical cystectomy (RC) and urethrectomy 19 and 2 years ago due to urothelial carcinoma, respectively. To the best of our knowledge, this is the second case of malignant priapism due to primary penile SCC and represents one of the longest urethral recurrence periods after RC. When a patient presents with malignant priapism, primary penile malignancies should be considered in differential diagnosis, even if the patient has a history of pelvic area malignancies.
Asian Journal of Medical Sciences, 2013
Metastatic neoplasms of the penis are uncommon. The most common primary organs have been reported to be the bladder and prostate. In the present report, a patient with priapism was demonstrated to have carcinoma prostate complicated with penile, lung, and liver metastasis in the absence of bone involvement and normal serum PSA levels.DOI: http://dx.doi.org/10.3126/ajms.v4i2.7827 Asian Journal of Medical Sciences 4(2013) 51-54
Cases Journal, 2009
Metastatic involement of penis is an exceptionally rare condition. 77% of the metastases are originated from the pelvic region; prostate and bladder are the most frequent primary locations. Retrograde venous route, retrograde lymphatic route, arterial spread, direct extension, implantation and secondary to instrumentation are the mechanisms of metastasis. Approximately two thirds of all penile metastasis are detected at a mean time of 18 months after the detection of the primary tumor and the remaining one third is presented at the same time with primary tumor. Diagnosis is usually made by biopsy and also non invasive methods as MRI or colour-coded duplex ultrasonography. Treatment options in these patients are local excision, partial or complete penectomy, external beam radiation therapy and chemotheraphy. Despite these alternatives prognosis is usually poor.
High flow malignant priapism with isolated metastasis to the corpora cavernosa
Urology, 1998
Malignant priapism is a rare disease with only 88 reported cases. We present a case of a patient with priapism secondary to isolated metastasis to corpora cavernosa from bladder tumor. Metastasis to penis usually represents evidence of a more widespread disease in 80% to 90% of the patients. Rarely, as in this case, the metastasis is solitary.
Penile metastasis from invasive bladder cancer
Acta chirurgica iugoslavica, 2009
Objective: To present the rare case of penile metastasis from bladder cancer. Patient report: A 68-year-old man with invasive bladder cancer disseminated in penile shaft and the pelvic lymph nodes is presented. The patient underwent cystoprostatectomy, total penectomy and adjuvant chemotherapy. Results: Ten months after surgery, patient is in complete remission. Conclusion: Despite the fact that secondary penile tumors usually require palliative therapy, in selected cases surgical treatment of primary tumor and penectomy, followed with chemotherapy, can improve survival.
A rare case of penile metastasis of testicular cancer presented with priapism
Hinyokika kiyo. Acta urologica Japonica, 2005
Priapism is thought as a condition of penile erection that persists beyond or is unrelated to sexual stimulation. Commonly two different entities of priapism are known, one is low-flow priapism and the other is high-flow priapism. It is important to distinguish these two conditions for the subsequent different treatments. We report a rare case of an indistinguishable priapism caused by penile metastasis of testicular cancer.
Prognosis of men with penile metastasis and malignant priapism: a systematic review
Oncotarget, 2018
Metastases to the penis are rare, but can have severe consequences. The aim of this study was to systematically review the literature in order to gain more information on the presentation and prognosis of this metastatic disease. We reviewed the literature relating to all case reports, series and reviews about penile metastasis, from 2003 to 2013, through a Medline search. We identified 63 articles and 69 patients. Metastases were located on the root (38.8%), the shaft (38.8%) or the glans (22.2%) of the penis. The diagnosis of penile metastasis was made after the primary cancer had been diagnosed. The most common presentation was a single small penile nodule. Ten patients reported priapism. The median survival time after diagnosis of penile metastasis was 10 months (range 6-18 months). A Kaplan-Meier analysis has shown that the patients presenting with priapism and those with metastases from non-urologic tumors have a significantly worse prognosis (age adjusted Log Rank: p=0.037 fo...
Transitional cell carcinoma of the bladder metastatic to the penis
Urology, 2004
Transitional cell carcinoma of the bladder has the potential to metastasize to multiple organs, and the vascularity of the penis makes it a potential site for hematogenous metastases. We present 2 cases of transitional cell carcinoma with metastases to the penis, with a review of the published reports involving penile metastases. We also discuss the presentation of penile metastases and relevant management issues in these patients who typically have quite advanced disease at presentation. UROLOGY 63: 981.e1-981.e3, 2004.