Suppression of Sost/Sclerostin and Dickkopf‐1 Augment Intervertebral Disc Structure in Mice
Tori Kroon
Journal of Bone and Mineral Research, 2022
View PDFchevron_right
Global Deletion of Sost Increases Intervertebral Disc Hydration But May Trigger Chondrogenesis
Tori Kroon
2020
View PDFchevron_right
Wnt Signaling Activates Shh Signaling in Early Postnatal Intervertebral Discs, and Re-Activates Shh Signaling in Old Discs in the Mouse
Debora Sinner
PLoS ONE, 2014
View PDFchevron_right
Molecular mechanisms involved in intervertebral disc degeneration and potential new treatment strategies
Daniel Ireland
Bioscience Horizons, 2009
View PDFchevron_right
Molecular Biology and Interactions in Intervertebral Disc Development, Homeostasis, and Degeneration, with Emphasis on Future Therapies: A Systematic Review
Mohammad Alkhdour
The Spine Scholar, 2017
View PDFchevron_right
Molecular Sciences Multiscale Regulation of the Intervertebral Disc: Achievements in Experimental, In Silico, and Regenerative Research
Jerome Noailly
International Journal of Molecular Sciences, 2021
View PDFchevron_right
Aging Mouse Partially Models the Aging Human Spine: Lumbar and Coccygeal Disc Height, Composition, Mechanical Properties and Wnt Signaling in Young and Old Mice
R. Aguilar, N. Holguin
Journal of Applied Physiology, 2014
View PDFchevron_right
Bone Density Ligand, Sclerostin, Directly Interacts With LRP5 but Not LRP5G171V to Modulate Wnt Activity
Debra Ellies
Journal of Bone and Mineral Research, 2006
View PDFchevron_right
The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain
Tony Freemont
Rheumatology, 2008
View PDFchevron_right
Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics
Mitchell levine
Current reviews in musculoskeletal medicine, 2015
View PDFchevron_right
Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy
Maria Jeziorska
The Journal of Pathology, 2002
View PDFchevron_right
The expression of osteoprotegerin is required for maintaining the intervertebral disc endplate of aged mice
Lianping Xing
Bone, 2011
View PDFchevron_right
Distinct modes of inhibition by Sclerostin on bone morphogenetic protein and Wnt signaling pathways
Olexandr Korchynskyi
2010
View PDFchevron_right
Multiscale Regulation of the Intervertebral Disc: Achievements in Experimental, In Silico, and Regenerative Research
Jerome Noailly
International Journal of Molecular Sciences
View PDFchevron_right
Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies
Richard Wubbolts
Arthritis Research & Therapy, 2013
View PDFchevron_right
Impaired Intervertebral Disc Development and Premature Disc Degeneration in Mice With Notochord-Specific Deletion of CCN2
Matthew McCann
Arthritis and Rheumatism, 2013
View PDFchevron_right
Impact of Wnt signals on human intervertebral disc cell regeneration
Ming Pei
Journal of Orthopaedic Research®
View PDFchevron_right
Proteomic Signature of the Murine Intervertebral Disc
Matthew McCann, Yizhi Xiao
View PDFchevron_right
Lumbar intervertebral disc degeneration associated with axial and radiating low back pain in ageing SPARC-null mice
Lina Naso, Maral Tajerian
Pain, 2012
View PDFchevron_right
Novel therapeutic strategies for degenerative disc disease: Review of cell biology and intervertebral disc cell therapy
Pranela Rameshwar
SAGE open medicine, 2018
View PDFchevron_right
Importance of Matrix Cues on Intervertebral Disc Development, Degeneration, and Regeneration
Judith Hoyland
International Journal of Molecular Sciences
View PDFchevron_right
Targeted Deletion of the SPARC Gene Accelerates Disc Degeneration in the Aging Mouse
Helene Sage
Journal of Histochemistry and Cytochemistry, 2005
View PDFchevron_right
Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration
Tony Freemont
Arthritis Research & Therapy, 2009
View PDFchevron_right
Pathophysiology of the human intervertebral disc
Giovanni Lombardi
View PDFchevron_right
A biological approach to treating disc degeneration: not for today, but maybe for tomorrow
Mauro Alini
Arthroplasty of the Spine, 2004
View PDFchevron_right
Canonical Wnt signaling in the notochordal cell is upregulated in early intervertebral disk degeneration
Björn Meij
Journal of Orthopaedic Research, 2012
View PDFchevron_right