Evaluation of antioxidant properties of secondary metabolites in aqueous extracts of Ficus thonningii blume tested on wistar rats (original) (raw)

2020, Journal of Analytical & Pharmaceutical Research

diabetes mellitus, gonorrhoea, respiratory infections, and mental illnesses. The leaves of F. thonningii contain various bioactive compounds which include alkaloids, terpenoids, flavonoids, tannins and active proteins, all of which contribute to its curative properties. In vitro and in vivo pharmacological studies revealed that F.thonningii possesses antimicrobial, anti diarrheal, anti helmintic, antioxidant, anti-inflammatory and analgesic properties. Scientific research has validated the ethno medicinal claims that F. thonningii is useful in disease management. However, there is need to continue identifying, isolating and quantifying the active principles and possibly determine the mechanisms underlying the curative properties of its bark. 2 It is in this context that the current study was conducted to investigate phyto chemically screen, evaluate the antioxidant of the stem bark extract on Wistar rats Materials and methods This was an experimental in vitro and in vivo preclinical study on Wistar rats conducted from the 11 November 2016 to the 25th May 2017. The study was done in the Preclinical Animal toxicology and