A Comparison of Germ Tube Production by Candidaalbicans in Three Media (original) (raw)
1998, Turkish Journal of Biology
Introduction C. albicans is a opportunistic pathogen and is dimorphic. The conversion of C. albicans from the commensal to the pathogenic state is associated with transition from the yeast cell to the hyphal form (1), although the evidence in support of this is equivocal (2, 3). This phenomenon of dimorphism must involve reorganization of the cell wall at the molecular level as revealed by detection of antigens and adhesins on hyphal-form cells (4-9). The morphological development of C. albicans can be described as follows: The yeast-form cell is the unicellular form of the fungus which propagates itself by budding. Under certain environmental conditions this form cell produces a cylindrical structure-the germ tube which is the initial morphological form of hyphae. The two parts are then described as the germ-tube portion and the yeast-cell portion. The whole structure is referred to as a hyphal-form cell (9).
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