A Recent Report on ‘Plants with Anti-Candida Properties’ (original) (raw)

2020, International Journal of Current Research and Review

Fungal infections are drawing attention because of the high mortality and morbidity rate associated with them. Candida, Cryptococcus, Pneumocystis, and Aspergillus are the main members of fungal genera responsible for life-threatening fungal infections all over the world. Candida exists as commensal opportunistic pathogens in the natural flora of human beings. Members of this genus have specialized virulence attributes which include adhesion, biofilm formation, yeast to hyphal transition, cell surface hydrophobicity, and secretion of hydrolytic enzymes. C. albicans, C. parapsilosis, C. glabrata, and C. tropicalis are key species, mainly responsible for 95% of candidiasis worldwide. Azoles, amphotericin B, echinocandins and terbinafine are the main synthetic drugs against the pathogens. Rising resistance to antifungals demands the development of alternative drugs, especially of plant origin. In this review, we have included the selected plants having significant anti-Candida potential, based upon recent studies.