Comparison between synthetic nuclear localization signal peptides from the steroid/thyroid hormone receptors superfamily (original) (raw)

ummarv:The main objective of the study is to demonstrate that short basic peptides from the :eroid/th-yroid hormone receptors superfamily act as Nuclear Localization Signals out of receptors )ntext. Such synthesized pepfides, chemically coupled to Bovine Serum Albumin,were shown to enable he corresponding BSA-conjugate to be transported to the nucleus. A second objective is to demonstrate he utility of viral cointernalization as a good method for rapid quantitation, comparison and competition i nuclear entry.