Field trial on the post-insemination intrauterine treatment of dairy cows with mild endometritis with cephapirin (original) (raw)
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The effect of intrauterine cephapirin on treatment of endometritis in commercial dairy cattle
To evaluate the effect of intrauterine cephapirin on treatment of endometritis 39 Holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. In experiment 1, 6 out of 14 cows were 25 to 30 days after parturition were treated by intrauterine oxytetracycline. Another 8 cows were treated by intrauterine cephapirin (Metri-Care). In experiment 2, 25 cows that were 55-60 days after parturition received three types of treatment. 6 cows were received only PGF2α, 9 cows were received PGF2α and procaine penicillin G, and 10 cows were treated by intrauterine Metri-Care. Cervical mucosa was collected before and after each treatment. There was no significant difference between mean (±SD) of neutrophils before and 14 days after treatment with them. Conception rates of cows received oxytetracycline and Metri-Care were 66.66% (4/6) and 37.5% (3/8), respectively. There was significant difference between mean of neutrophils before a...
The effect of treatment of clinical endometritis on reproductive performance in dairy cows
Journal of dairy science, 2002
The objective of this field trial was to compare the effect of intrauterine (i.u.) antibiotic or intramuscular (i.m.) prostaglandin F2 alpha (PGF2 alpha) on time to pregnancy in dairy cows diagnosed with clinical endometritis between 20 and 33 days in milk (DIM). The case definition of endometritis was the presence of purulent uterine discharge or cervical diameter > 7.5 cm, or the presence of muco-purulent discharge after 26 DIM. There were 316 cows with endometritis from 27 farms assigned randomly within herd to receive 500 mg of cephapirin benzathine intrauterine (i.u.), 500 micrograms of cloprostenol i.m., or no treatment. The rate of resolution of clinical signs 14 d after treatment was 77% and was not affected by treatment. Reproductive performance was monitored for a minimum of 7 mo after treatment. Survival analysis (multivariable proportional hazards regression) was used to measure the effect of treatment on time to pregnancy. There was no benefit of treatment of endomet...
Turkish Journal of Veterinary and Animal Sciences
Subclinical endometritis contributes to repeat breeder syndrome in dairy cows. This study evaluated the effect of intrauterine cephapirin benzathine administration aft er timed artificial insemination (TAI) on the conception rate (CR) in repeat breeder dairy cows. To determine the antibiotic effects, all cows (n = 335) that had more than 3 services with no clinical abnormalities of the reproductive tract received the same combined synchronisation protocol: an ear implant containing progestagen using the Ovsynch protocol and a third gonadotropin-releasing hormone (GnRH) administration 7 days aft er TAI. Cows in the treatment group (TRT; n = 160) received intrauterine cephapirin 12 h aft er TAI, and cows in the control group (CON; n = 175) did not receive intrauterine antibiotics. The percentage of cows that responded to the first (67.5% in TRT, 70.9% in CON) and second (98.8% in TRT, 97.1% in CON) GnRH of Ovsynch was similar between the groups. In addition, the response to the third ...
2016
The aim of this study was to test treatment of clinical endometritis in the early postpartum (PP; group A; 5-10 day after calving) and late PP (group B; 30-35 day PP) using systemic administrations of ceftiofur with two injections of PGF2α at intervals of 8 h. Examination of vaginal discharge, determination of plasma progesterone (P4), measurement of acute phase proteins (APP), histological examination of uterine biopsies and fertility parameter data were used for evaluation of treatment success. No significant differences in improvement of vaginal discharge, the start of ovarian activity, the length of the first luteal phase measured by P4, or in the time-trends of APP and presence of subclinical endometritis on days 43-45 PP, based on histological examination, were detected. Fertility parameters of group A were better than in group B. However, this difference was not significant, possibly because of the small experimental groups.