Prognostic model for traumatic death due to bleeding: cross-sectional international study (original) (raw)
ObjectiveTo develop and validate a prognostic model and a simple model to predict death due to bleeding in trauma patients.DesignCross-sectional study with multivariable logistic regression using data from two large trauma cohorts.Setting274 hospitals from 40 countries in the Clinical Randomisation of Anti-fibrinolytic in Significant Haemorrhage (CRASH-2) trial and 24 hospitals in the Northern French Alps Trauma registry.Participants13 485 trauma patients in the CRASH-2 trial and 9945 patients in the Northern French Alps Trauma registry who were admitted to hospital within 3 hours of injury.Main outcome measureIn-hospital death due to bleeding within 28 days.ResultsThere were 815 (6%) deaths from bleeding in the CRASH-2 trial and 102 (1%) in the Northern French Alps Trauma registry. The full model included age, systolic blood pressure (SBP), Glasgow Coma Scale (GCS), heart rate, respiratory rate and type of injury (penetrating). The simple model included age, SBP and GCS. In a cross...
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