Bone Morphogenetic Protein 2 Activates Smad6 Gene Transcription through Bone-specific Transcription Factor Runx2 (original) (raw)
Loss of Smad3-Mediated Negative Regulation of Runx2 Activity Leads to an Alteration in Cell Fate Determination
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SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation
Eliana S. F. W. Abdelhay
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Smad6 Represses Dlx3 Transcriptional Activity through Inhibition of DNA Binding
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CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter
Edward Schwarz
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Runx2 Is a Common Target of Transforming Growth Factor β1 and Bone Morphogenetic Protein 2, and Cooperation between Runx2 and Smad5 Induces Osteoblast-Specific Gene Expression in the Pluripotent Mesenchymal Precursor Cell Line C2C12
Eung-Gook Kim
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SWI/SNF-Independent Nuclease Hypersensitivity and an Increased Level of Histone Acetylation at the PI Promoter Accompany Active Transcription of the Bone Master Gene Runx2
Berta Henriquez, Fernando Cruzat
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SWI/SNF-Independent Nuclease Hypersensitivity and an Increased Level of Histone Acetylation at the P1 Promoter Accompany Active Transcription of the Bone Master Gene Runx2
Alejandro Villagra
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Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads
Carl-henrik Heldin
The EMBO journal, 2001
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Human Smad3 and Smad4 Are Sequence-Specific Transcription Activators
le Dai
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Bone Morphogenetic Protein-2 Stimulates Runx2 Acetylation
Mi-hye Lee
Journal of Biological Chemistry, 2006
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Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase
Chenbei Chang
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Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor β-related signaling
Robert Maxson
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Smad3 activates the Sox9-dependent transcription on chromatin
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Menin is required for bone morphogenetic protein 2- and transforming growth factor β-regulated osteoblastic differentiation through interaction with Smads and Runx2
Lucie Canaff
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Identification of a new human Smad6 splice variant
Lutz Konrad
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Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins
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Targeted Disruption in Murine Cells Reveals Variable Requirement for Smad4 in Transforming Growth Factor beta -related Signaling
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Smad3 and Smad4 Mediate Transcriptional Activation of the Human Smad7 Promoter by Transforming Growth Factor beta
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Transcriptional regulation of Smad2 is required for enhancement of TGF?/Smad signaling by TGF? inducible early gene
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Regulation of the osteoblast-specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways
Sharon Dent
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Smads oppose Hox transcriptional activities
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Experimental Cell Research, 2006
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Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-beta Signaling
Serhiy Souchelnytskyi
Journal of Biological Chemistry, 1997
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Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1
Kai Jiao
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Transforming growth factor β inhibits bone morphogenetic protein-induced transcription through novel phosphorylated Smad1/5-Smad3 complexes
Eva Grönroos
Molecular and cellular biology, 2012
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SMAD1/5 signaling in osteoclasts regulates bone formation via coupling factors
Kim Mansky
PLOS ONE, 2018
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Dominant-Negative SMAD-3 Interferes with Transcriptional Activation by Multiple Agonists
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