Sequences related to mouse mammary tumor virus genome in tumor cells and lymphocytes from patients with breast cancer (original) (raw)

1984, Biochemical and Biophysical Research Communications

AI-generated Abstract

This research investigates the presence of murine mammary tumor virus (MuMTV) related sequences in human breast cancer tissues and lymphocytes. Of 28 analyzed tumors, two contained homologous sequences to MuMTV, detected through hybridization techniques. Cultured lymphocytes from patients presented these sequences, contrasting with fresh lymphocyte DNA, which was negative. The findings suggest a potential link between MuMTV and human breast cancer, warranting further exploration into its role in tumorigenesis.