Antimicrobial activity of three hard coral species from South China Sea (Malaysia) (original) (raw)

2014

Abstract

The problem of antimicrobial drug resistance has necessitated a search for new antimicrobial substances from other sources including natural sources. Marine organisms are known to produce metabolites to protect themselves against pathogens and therefore can be considered as a potential source of antimicrobial substances. This study designed to evaluate the antimicrobial activity of three hard coral species namely Favites sp Link (Faviidae), Galaxea fascicularis Linnaeus (Oculinidae), and Galaxea astreata Lamarck (Oculinidae) against six pathogenic microbes. The coral species were extracted with water and a combination of dichloromethane and methanol. The antimicrobial activity of the extracts was evaluated using disc diffusion method and microdilution method. From the disc diffusion method, the organic extracts showed antimicrobial activity while the aqueous extracts showed no activity. The organic extract from G. fascicularis was the most effective against Staphylococcus aureus (11...

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