Comments on How to Perform Valid Ultrasound Measurements of Carotid Artery Intima-Media Thickness and Lumen Diameter (original) (raw)
The joint experience from many research laboratories around the world shows that high quality 2-D ultrasound images may be recorded from the common carotid artery and the carotid artery bulb. In most cases, the image from the carotid artery shows a typical double-line pattern similar in appearance from the near and far wall of the artery. In spite of the similarity of the near and far wall images the thickness of the intima-media complex can only be measured in a valid way in the far wall position. This is because it is only in the far wall that the intima-media complex is defined by leading edges from echoes of interest. In vitro experiments and measurements of arterial wall segment thicknesses obtained by histology and by vascular ultrasound also confirm that only far wall intima-media thickness, in contrast to near wall thickness, may be accurately measured. The anatomical location of a biological structure is always defined by a leading edge of an echo, and the thickness of a st...
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