0213 Circadian Entrainment and Cognition in College Students using Antidepressants (original) (raw)

Introduction Depression, sleep disturbances, and cognitive deficits often co-occur. Compared to non-medicated controls, people using antidepressant medications (particularly serotonin agonists) often have improved sleep including increased slow wave sleep, quality and continuity. Improvements to cognition after antidepressant treatments are also common including benefits to reaction time, inhibition, and memory. Importantly, circadian deficits, including sleep onset latency, fragmentation, and phase shifts are common in patients with depression, yet the effect of antidepressant medication on circadian indicators is unclear. The current project examined sleep, circadian entrainment, and cognition in college students who were diagnosed with depression and using serotonin agonists and in those without depressive symptoms. Methods Participants completed cognitive tasks that assessed reaction time, memory, attention, inhibition, and logical reasoning via the Automated Neuropsychological ...