A Case Report on Malaria (original) (raw)
Related papers
To Study the Different Clinical Presentation of Malaria
International Journal of Medical and Biomedical Studies, 2020
This study was done at Department Of Medicine. All patients admitted with malaria in tertiary care Centre during the study period August 2017 to July 2018 were taken for the study after considering the inclusion and exclusion criteria. Our study is a clinical, prospective, observational and open study. Result: Fever occurred in all patients, and it was intermittent in 72.5% of the cases, continuous in 17.5% of the cases and remittent in the remaining 10%. Intermittent fever is the commonest. All 100% patients had chills and rigors. Most of the Patients (65%) had presented with acute illness of 2-10 days duration of fever. Bifrontal dull aching to throbbing headache associated with fever was presenting clinical symptoms in 92% of patients. Most of the patients complained of generalized weakness, malaise and myalgia. Cerebral manifestation is seen in 10% of patients. Spleenomegaly was predominant in 64% of patients and 40% patient had hepatomegaly. Patient with mixed infection had more propensity to develop systemic complication. Conclusion: Malaria is an age-old disease of mankind, caused by protozoal plasmodium and transmitted by anopheles mosquito. It is prevalent throughout most tropical countries. Both species are commonly presented with symptoms of intermittent Fever, chills, Bi-frontal headache, vomiting and commonly clinical feature is splenomegaly. Severe complication like anemia, thrombocytopenia jaundice, acute renal failure and sometimes life threatening cerebral malaria are need to address promptly to avoid adverse outcome.
International Journal of Advances in Medicine, 2016
Malaria continues to be one of the important public health problems in India. As per World Health Organization report 2015, South East Asian Region bears the second largest burden of malaria (10%), only being next to African region (88%).Malaria caused 214 million infections and 438000 deaths worldwide, most of them occurred in the Africa region (90%) followed by SEA Region (7%). 1 Among Southeast Asia region, India shares two-thirds of the burden (66%) followed by Myanmar (18%) and Indonesia (10%). 2 The malaria situation remains a major problem in certain states and geographical pockets. The majority of malaria cases and deaths in India are being reported from Orissa, Rajasthan, Jharkhand, Chhattisgarh, Madhya Pradesh and the Seven North Eastern states. 3 Malaria is caused by protozoan parasite of genus plasmodium. Five species of the plasmodium P. Falciparum, P. Vivax, P. Ovale, P. Malariae and P. Knowlesi cause malaria in humans. Infection is initiated when sporozoites from the salivary glands of a female anopheles mosquito are inoculated during a blood meal into the human blood stream. 4 The common clinical manifestation are fever with chills and rigors, headache, vomiting, jaundice and common sign being splenomegaly, pallor, and icterus. 13,22-23 Hematological abnormality which is most commonly seen in malaria is thrombocytopenia followed by anemia. Both are seen ABSTRACT Background: Malaria continues to be one of the important public health problems in India. As per World Health Organization report 2015, South East Asian Region bears the second largest burden of malaria (10%), only being next to African region (88%).The present study is aimed at to study clinical profile and complications, in a tertiary care hospital. Methods: A total of 100 cases were included in the study that admitted at NMCH, Kota and identified positive for malaria parasites on peripheral smear examination with conventional microscopy and / or by rapid diagnostic test. Results: predominant symptoms were fever (100%), vomiting (52%), headache (34%), myalgia (28%) and jaundice (27%) and signs were splenomegaly (75%), pallor (57%), icterus (28%), hepato-splenomegaly (19%), and hepatomegaly (04%). In this study, 82% patients suffered from uncomplicated malaria and 18% from complicated malaria. Conclusions: Malaria is responsible for major health concern in Southeastern region of Rajasthan and is found to affect comparatively the younger adult population. P. Vivax was the major parasite type causing malaria and most of the complications were due to P. falciparum.
The changing clinical spectrum of Malaria: a clinical study from Bundelkhand
IOSR Journal of Dental and Medical Sciences, 2014
Objective: To find out clinical and laboratory findings in acute malaria caused by various plasmodium species. Methods: This was a prospective study which was carried out in the department of medicine at MLB Medical College ,Jhansi from May 2012 to September 2013.In this prospective study ,401 patients of malaria were enrolled who met both inclusion and exclusion criteria. Frequencies of alterations in clinical and laboratory parameters were determined in various plasmodium species. Results: Out of 401 patients, 194 were Plasmodium falciparum, 185 were P.vivax and 22 were mixed infection. Fever (97.5%), chills and rigors (84.7%) were the most common complaint in all three varieties of plasmodium infection. Pallor (78.3%) and splenomegaly (56.6%) were often detected in individuals with malaria. Thrombocytopenia (52.8%) was most common laboratory abnormalities detected in various plasmodium species. Jaundice and anemia were more common in P.falciparum and mixed infection as compared to P.vivax Conclusion: Malaria must be considered as leading differential diagnosis in an acutely febrile patient with one or more of abnormalities like splenomegaly, fall in blood counts or rise in bilirubin etc. Fever with chills and rigors, pallor, splenomegaly and thrombocytopenia were most common manifestation in malaria.
Hematological Profile of Patients with Malaria at Tertiary Care Hospital
Zenodo (CERN European Organization for Nuclear Research), 2019
All the patients with ≥01 year of age of either gender presented with fever and chills, headache were recruited in the study and explored for malaria parasite. The relevant patients had blood complete picture (CP), MP and immunochromatographic test (ICT) to evaluate the malaria and its pattern along with exploration of hematological parameters while the frequency / percentages (%) and means ±SD computed for study variables. RESULTS: During one-year study period, total three thousand, five hundred and four (3504) patients were detected as malaria with means ± SD for age (yrs), WBC, hemoglobin and platelet was 57.99±10.93, 12,500±7.96, 9.87±5.52 (gm/dL) and 10,9000 ± 15.83Respectively. Out of 3504, two thousand five hundred and fifty patients-2550 (72.7%) were males and 954 (27.2%) were females. The anemia, leucocytosis, leucopenia, lymphocytosis, lymphopenia and thrombocytopenia was observed in 74%, 55%, 27%, 37%, 17% and 80% while among leucocytosis neutrophilia (36%), monocytosis (12%), eosinophilia (5%) and basophilia (2%). CONCLUSION: The hematological changes are common complications encountered in.
A brief review on Malaria Disease (Causes, Treatment, Diagnosis)
2019
Malaria is caused by a parasite called Plasmodium, which is transmitted via the bites of infected mosquitoes. In the human body, the parasites multiply in the liver, and then infect red blood cells. The human malaria parasite has a complex life cycle that requires both a human host and an insect host. In Anopheles mosquitoes, Plasmodium reproduces sexually (by merging the parasite's sex cells).
The study of clinical, biochemical and hematological profile in malaria patients
International Journal of Advances in Medicine, 2016
Malaria is a febrile illness characterized by fever and related symptoms; however it is very important to remember that malaria is not a simple disease of fever, chills and rigors. The number of atypical presentations of malaria has gradually increased during the past few decades. 3 Malaria can present with non-specific symptoms like headache, ABSTRACT Background: Malaria is a major health problem in India. Malaria is the most important parasitic infection which causes major health challenges. Malaria pathogenesis is based on extensive changes in hematological and biochemical parameters. The objective of this study was to study the clinical features, hematological and biochemical parameters in malaria patients and correlate them. Methods: The present study was done in the department of medicine, M.G.M.M.C & M.Y.H. Indore (M.P.). In this study various signs and symptoms and frequency of changes in hematological and biochemical parameters caused by Plasmodium species were determined. Mean, standard deviation, minimum, maximum values of laboratory alterations were noted and associations were calculated. Results: 104 patients who had peripheral smear positive for malaria parasite were included in this study. Out of these 104 patients 53 (50.96%) patients of P. falciparum, 48 (46.15%) patients of P. vivax and 3 (2.88%) patients of mixed infection. In the present study most common system involved was haematological (69%) followed by hepatic (42.3%), renal (29.04%), neurological (28.84%), cardiovascular (16.34%) and pulmonary (2.88%). Conclusions: Malaria though potentially treatable, still kills many patients every year in India. The most common presentation of malaria is fever, so in endemic region malaria may be considered as a leading differential diagnosis in all patients presenting as acute febrile illness, especially patients who also have organomegaly, fall in hemoglobin level, thrombocytopenia and altered liver function tests. Therefore, it is vital to know and perform hematological and biochemical investigations to detect early complications and to treat them effectively.
IOSR Journals , 2019
STUDY POPULATION: Study was done on admitted cases of patients above 18yrs suffering from P.falciparum malaria who have been confirmed either by peripheral blood film or rapid diagnostic tests in Medicine Department of RIMS. INCLUSION CRITERIA :All malaria cases satisfying at least one or more parameters of criteria such as unconsciousness, convulsions, high grade fever, anaemia, shock, increased serum creatinine and urea, oliguria, jaundice, hepatomegaly, splenomegaly, vomiting, abdominal pain, bleeding from abnormal site, headache were considered as complicated malaria cases. Respondent: In unconscious and severely ill non co-operative patients respondent were their attendants. SAMPLING PROCEDURE: Every consecutive case satisfying the inclusion criteria was studied. SAMPLE SIZE: 52 cases studied during the time period.
Clinical Spectrum of Severe Plasmodium falciparum Malaria in a Tertiary Care Centre of Eastern India
Introduction: Plasmodium falciparum malaria is one of the major public health problem presented with varied clinical severity. This study was carried out to observe the clinical spectrum of severe falciparum malaria in a tertiary health care centre. Methods: This study was undertaken in hospitalized adults with suspected severe malaria. Confirmation of falciparum infection was done by ICT/QBC and single-step-PCR. Diagnosis of severe malaria was done by WHO-guideline 2010. Original Research Article Purohit et al.; IJTDH, 12(4): 1-11, 2016; Article no.IJTDH.22387 2 Results: 450 adult cases with falciparum infection were studied. Maximum number of cases was from 15-25 years age group depicting the high exposure to malaria. In these patients, acute renal failure (ARF) was the most common (36.2%) complication followed by cerebral malaria (35.3%), jaundice (27.8%), hepatic dysfunction (21.8%), respiratory distress (18.4%), severe malarial anemia (15.8%), thrombocytopenia (15.1%), and hypoglycemia (9.3%). Mortality was found in 6.0% of cases. Cerebral involvement and ARF were the common cause of death in these patients. Conclusion: ARF is the most common type of clinical severity followed by cerebral malaria in adults and both are equally responsible for death along with other complications. Looking into the matter of varied clinical severity, accurate diagnosis, effective anti-malarial treatment along with supportive therapy is necessary to triumph over this deadly severe falciparum malaria.