Visual performance of silicone hydrogel daily disposable contact lenses (original) (raw)
Related papers
Visual and optical performance of silicone hydrogel contact lenses for moderate myopia
Journal of Optometry, 2010
To compare the short-term visual and optical performance of silicone hydrogel contact lenses for myopia ≥-3.00D. Methods: This was a short-term, non-dispense, double-masked, randomized study investigating Night&Day (ND), PureVision (PV), O2 Optix (O2), Bio nity (BF), Acuvue Advance (AA) and Acuvue OASYS for myopia ≥-3.00D. Testing was conducted under scotopic conditions. Measures (one eye only) included: high-and low-contrast visual acuity (HCVA/LCVA), contrast sensitivity, subjective clarity of vision ratings (0-100 scale using reference images, with test image representing grade 50) and ocular aberrations (up to the 4th order, analyzed across individual scotopic pupil sizes). Results: Three males and 27 females participated, with a mean (± SD) age of 24.9 ± 7.7 yrs (range 19 to 53 yrs), sphere of-5.30 ± 1.73D (range-3.00 to-10.75D) and cylinder-0.36 ± 0.23D (range 0 to-0.75D). Mean (± SEM) logMAR HCVA ranged from 0.06 (PV) to 0.10 (AA) (± 0.02), LCVA from 0.33 (BF) to 0.40 (AA) (± 0.02) and contrast sensitivity from 2.33 (BF) to 2.53 (ND) (± 0.15) (differences not statistically signi cant; all p > 0.05). Subjective ratings for the test image ranged from 59 (PV) to 64 (ND) (± 4) and 56 (AA) to 65 (ND) (± 4), for monochromatic and polychromatic reference images, respectively (all p > 0.05). There was a statistically signi cant impact on ocular aberrations with all study lenses compared to no lens. Between-lens differences were statistically signi cant for defocus (Z 0 2), horizontal coma (Z 1 3) and spherical aberration (Z 0 4). Conclusions: Despite some differences in ocular aberrations, there were no signi cant differences in HCVA, LCVA, contrast sensitivity or subjective ratings across lenses.
Contact Lens and Anterior Eye, 2013
Purpose: To evaluate the performance of a silicone hydrogel daily disposable lens in neophyte subjects over 12 months. Methods: Seventy four subjects with no previous contact lens experience were randomised to wear narafilcon A (1 DAY ACUVUE ® TruEye TM ) lenses (LW group) or to wear no contact lenses (NLW group) for 12 months. Biomicroscopy (performed by a masked investigator), visual acuity and subjective response scores were recorded at an initial visit and six follow-up visits, in addition to lens fit and surface evaluation for the LW group. Comfort was recorded with SMS messaging. Results: Fifteen of the LW group discontinued before the end of the study, compared with six of the NLW group. Measured visual acuity was about half a line better for the NLW group as these subjects were provided with their full sphero-cylindrical over-refraction, compared to the LW group in their best spherical corrected contact lenses; subjective scores for vision were similar for the two groups. Bulbar conjunctival hyperaemia, limbal hyperaemia, corneal staining, conjunctival staining and papillary conjunctivitis were clinically equivalent for the two groups whereas conjunctival staining was higher in the LW group. Comfort scores assessed by SMS were equivalent for the LW and NLW groups; there was a measurable improvement in comfort during the first month of wear for the LW group.
2004
Purpose: It is possible that many reports of topographical and refractive changes associated with silicone hydrogel contact lens wear are the result of inadvertent wearing of inverted lenses. We wished to investigate differences in subjective, topographic, and refractive impact of wearing inverted silicone hydrogel lenses in comparison to wearing lenses in the normal (non-inverted) configuration. Methods: Baseline uncorrected visual acuity and topographical maps were taken for 14 subjects, and a comfort survey was completed for each. The subjects were then fit with Focus Night & Day (Ciba Vision) silicone hydrogel contact lenses; one of the two lenses was inverted on each subject, as determined by a randomized, masked schedule. Lenses were removed after 12 hours that included overnight wear. Acuities, topographical maps and the comfort survey were then repeated. Results: Significant change was noted from baseline for both lens conditions for acuities (p<0.01) and the topographica...
Impact of contact lens material and design on the ocular surface
Clinical and Experimental Optometry, 2017
Background: To evaluate the impact on the ocular surface of a daily disposable hydrogel contact lens with high water content compared with two silicone hydrogel daily disposable lenses of lower water content. Methods: The hydrogel lens assessed was made from nesofilcon A and the silicone hydrogel lenses were made of delefilcon A and stenfilcon A. Contact lens thickness was measured to assess material stability during daily wear, and ocular surface parameters such as tear film osmolarity, tear meniscus area and central corneal thickness were also assessed. Optical quality was analysed for all cases by means of wavefront aberrometry. Results: The nesofilcon A was shown to be the thinnest lens (p < 0.001), while no differences in lens thickness were found between the two silicone hydrogel lenses (p = 0.495). No significant differences were found in tear film osmolarity, tear meniscus area, central corneal thickness or corneal aberrations, either as a function of the lens measured or time of use (p > 0.05). Conclusion: In spite of having the thinnest lens and the highest water content, the hydrogel does not significantly impact on tear film and corneal swelling after one day of use in first-time wearers.
Eye & Contact Lens: Science & Clinical Practice, 2008
Purpose. To evaluate the effect of negatively powered soft contact lenses on ocular higher-order aberrations (HOAs). Methods. HOA measurements were performed with fixed optical zones of 4.0 and 6.0 mm on 20 eyes of 10 participants before and minutes after wearing extended-wear Focus NIGHT & DAY contact lenses. For each eye, three contact lens powers were used: Ϫ2.00 diopters (D),-4.00 D, and a power equal to the spherical equivalent of each eye. Results. The change in spherical aberration was highly correlated with the change in negative power of the contact lens at an optical zone of 4 and 6 mm (Pearson correlation coefficient ϭ 0.914 and 0.743, respectively, PϽ0.0001). Total HOAs had a weaker but important correlation at an optical zone of 6 mm (Pearson correlation coefficient ϭ 0.470, Pϭ0.037) and insignificant correlation at an optical zone of 4 mm. Coma and trefoil were poorly correlated with contact lens power in either optical zone. Compared to the control using both optical zones, the-2.00 D contact lens resulted in a significant increase in total HOAs and spherical aberration, whereas the-6.00 D lens yielded a marked decrease in spherical aberration and a mild, statistically insignificant increase in total HOAs. Both contact lens powers yielded larger ocular coma and unchanged trefoil levels. The change from induction to reduction of spherical aberration occurred at-4.00 D. Conclusions. The Focus NIGHT & DAY lens vehicle harbors positive spherical aberration and coma, independently of the lens power. The negative power of contact lenses induces negative spherical aberration, which, at large values, compensates for the lens vehicle positive spherical aberration to produce a net negative spherical aberration.
Clinical Comparison of a Silicone Hydrogel and a Conventional Hydrogel Daily Disposable Contact Lens
Clinical Ophthalmology, 2021
Purpose: To compare the subjective performances of verofilcon A daily disposable silicone hydrogel contact lenses (CLs) and etafilcon A hydrogel CLs. Methods: Successful wearers of spherical soft CLs for distance correction were prospectively randomized to wear verofilcon A or etafilcon A lenses for 1 week and crossed over to the alternative lenses. The primary study objective was a comparison of distance visual acuity (VA). Exploratory endpoints included subjective overall lens preference (5-point scale) and subjective ratings (10-point scales) of end-of-day (EOD) vision, overall handling, insertion comfort, EOD comfort, overall quality of vision, overall comfort, vision throughout the day, lens handling at insertion, and lens handling at removal. Results: Of 92 subjects (184 eyes), 46 each were randomized to verofilcon A or etafilcon A lenses and subsequently crossed over to the other lenses. Evaluation of distance VA showed that verofilcon A lenses were noninferior to etafilcon A lenses. Comparison of lens preference showed that 68 (73.9%) subjects somewhat or strongly preferred verofilcon A lenses, whereas 21 (22.9%) somewhat or strongly preferred etafilcon A lenses (p<0.0001). Mean ± SD ratings of EOD vision (8.6±1.5 vs 7.7±1.9), overall handling (8.7±1.5 vs 6.9 ±2.3), insertion comfort (9.2±1.0 vs 7.7±1.9), and EOD comfort (8.0±1.9 vs 7.0±2.2) were all significantly (p≤0.0001 each) higher for verofilcon A than for etafilcon A lenses. Mean ± SD ratings of overall quality of vision (8.9±1.2 vs 8.2±1.8), overall comfort (8.6±1.5 vs 7.4 ±1.8), vision throughout the day (8.9±1.3 vs 8.1±1.8), lens handling at insertion (9.0±1.4 vs 6.9±2.5), and lens handling at removal (8.3±2.1 vs 7.7±2.2) were also significantly higher for verofilcon A lenses. No subject experienced any ocular adverse events. Conclusion: After 1 week of wear, the study population reported that ratings for subjective endpoints were significantly higher for verofilcon A lenses than for etafilcon A lenses.
New Option in Conventional Silicone Hydrogel Contact Lenses: The Brazilian Experience
Vision Pan-America, The Pan-American Journal of Ophthalmology, 2015
PURPOSE: To evaluate the clinical performance of a new conventional silicone hydrogel contact lens in spherical and toric designs. METHODS: We fitted the Perfect SH and Perfect Toric SH (World Vision Ophthalmic ® , Brazil) in 19 patients (33 eyes). Contact lens material was Filcon II (hydration: 74%; Dk: 60 x 10-11@35C). We evaluated demographics (sex, age), also if the patient had tried to wear contact lenses before, best-corrected visual acuity with spectacles and with contact lenses, spherical equivalent of the refraction, design of the fitted lenses (between spherical and toric), keratometry, the base-curve of the fitted lenses, the occurrence of complications, and patient’s satisfaction with the new lenses. RESULTS: Fourteen patients were female (73,7%) and five were male (26,3%). The average spectacle-corrected visual acuity (LogMAR) was 0,31 ±0,35. The LogMar visual acuity with contact lenses was 0,25±0,29. Seventeen (89,4%) patients were satisfied with the new contact lens a...
Changes in the geometry of modern daily disposable soft contact lenses during wear
The geometry of contact lenses can be altered by wear but determining the changes that occur in soft contact lenses (SCLs) is challenging. This study aimed to investigate the shape alterations of daily disposable SCLs after wear using swept-source optical coherence tomography (SS-OCT). Forty-five eyes with myopia of − 3.00 diopters (D) were enrolled. The participants wore three types of SCLs: hydrogel lens (nesofilcon A) and silicone hydrogel lenses (delefilcon A and stenfilcon A). The SCLs were scanned 3-6 min after lens removal. We found a significant decrease in the SCL anterior curvature: 0.24 ± 0.17 mm for nesofilcon A, 0.44 ± 0.21 mm for delefilcon A, and 0.53 ± 0.29 mm for stenfilcon A. The changes in the anterior curvature of SCLs correlated moderately with the mean corneal keratometry; Pearson's correlation coefficients for nesofilcon A and delefilcon A were 0.57 and 0.52, respectively (P < 0.001). A statistically significant change in the total diameter was observed in SCL made of stenfilcon A (0.39 mm, P < 0.001). To conclude, the central radii of curvature decreased after a wearing period for all three types of daily disposable SCLs to imitate the anterior corneal surface, however, the changes in other geometrical parameters measured with SS-OCT were lens-specific. Refractive errors are often corrected with soft contact lenses (SCLs). However, despite their many advantages, daily disposable SCLs are not the most frequently chosen lenses by patients due to a lack of awareness of this option or concerns about possible complications 1. Nevertheless, we have recently observed an overall increase in the usage of daily disposable SCLs due to the lower risk of infection and inflammation compared with extended (sleeping with SCLs) or continuous (using SCLs for thirty days and nights) monthly SCLs. Moreover, daily SCLs are less likely to accumulate deposits of proteins and lipids that impair vision and cause discomfort. Furthermore, apart from using proper hygiene when inserting or removing the contact lenses, patients do not have to perform daily care of their contact lenses 2-4. Current SCLs are manufactured with two types of materials: hydrogel and silicone hydrogel. In recent years, continuous development of silicone hydrogel materials have included modification to the lens's surface to improve patient comfort by increasing material wettability and biocompatibility with a tear film. SCLs material properties such as elasticity, viscosity, and yield strength are determined by the characteristics of the material, including water content and Young's modulus. The water content of materials can range from 30 to 80% 3,5. Additionally, Young's modulus of lens material varies between 0.3 and 1.5 MPa 6. These material properties allow adjustments of the SCL interface curvature to the shape of the anterior cornea during wear 5-7. However, little scientific data has been reported regarding whether this change is temporal (only on the eye) or might be present after removal. Geometrical interactions between SCLs and the surface of the eye have a significant impact on the lens performance in terms of comfort and vision quality 8-10. This knowledge might be useful in the development of new designs and materials for daily disposable SCLs, which are supposed to be the type of lenses most frequently used in the future, especially considering the revolutionary projects of SCLs containing electronic components 11-13. Contact lens design is usually described by back optic zone radius, back optic zone diameter, total diameter, back vertex power, or central thickness 1. Although several techniques to determine the curvatures and shapes of SCLs are available, the measurements are difficult to obtain and have issues with repeatability and reproducibility, mainly due to the instability of SCLs 14. The radii of curvature can be measured by radiuscope, keratometer, toposcope, microspherometer, and other instruments. The lens diameter can be obtained by projector magnifier, 10 × loupe with graticule, or moiré fringe deflectometer. While the lens thickness can be assessed with an electronic/
Ophthalmic and Physiological Optics, 2009
Purpose: To study the effects on visual performance of a novel custom hydrogel contact lens, which employs a correction for vertical coma aberration, in keratoconic eyes. Methods: Six subjects (8 eyes) with mild or moderate keratoconus were recruited for the study. Preliminary measurements included corneal topography, wavefront aberrometry, subjective refraction, visual acuity (VA) and 50% contrast VA. Based on the aberrometry data, customized lenses were made and fitted to the subjects. Evaluation of the on-eye performance of the lenses was carried out, including wavefront aberrometry, over-refraction, VA and 50% contrast VA. In two of the subjects, both eyes were fitted with the customized lenses, and binocular performance was evaluated. Results: Monocular visual performance with a 4 mm pupil, with the lenses worn, was improved, and reached the mean values of )0.003 (LogMar units) of 100% high contrast VA, and 0.049 (in LogMar units) of 50% contrast VA. Vertical coma aberration and total higher-order aberrations (HOAs) were reduced (naked eyes: )0.64 ± 0.21 root mean square (rms) of vertical coma and 0.86 ± 0.15 rms of total HOAs; with the lenses worn: )0.29 ± 0.23 rms of vertical coma and 0.57 ± 0.17 rms of total HOAs, all for a 4 mm pupil). Binocular VA results from two of the subjects were on average )0.040 (LogMar units) 100% high contrast acuity and )0.060 (LogMar units) 50% contrast visual acuity. Conclusions: Customized hydrogel contact lenses implementing correction of vertical coma, have been found to improve both monocular and binocular visual performance of eyes affected with mild or moderate keratoconus.
Current Eye Research, 2017
Purpose: To evaluate the effects of three different silicone hydrogel contact lenses (SHCL), (balafilcon A, senofilcon A, and comfilcon A) on tear function tests, corneal thickness, and ocular surface cytology in first time contact lens users. Materials and methods: In this prospective study, 120 eyes of 60 subjects were evaluated. Balafilcon A users were designated as group 1, senofilcon A users as group 2, and comfilcon A users as group 3. In all cases, before and after 6 months of contact lens wear, ocular surface disease index score (OSDI), tear breakup time (TBUT), Schirmer 1 test, central corneal thickness (CCT), central corneal epithelium thickness (CCET), and conjunctival impression cytology samples were evaluated. Results: In group 1, 40 eyes of the 20 patients, in group 2, 40 eyes of the 20 patients, and in group 3, 40 eyes of the 20 patients were evaluated. The mean OSDI scores did not differ between the three groups after contact lens wear (p > 0.05). In group 1 and group 2, significant decrease was found in the mean TBUT 6 months after contact lens wear (p = 0.04, p < 0.001, respectively). In group 3, after 6 months of contact lens wear, the mean Schirmer 1 tear test was decreased significantly (p = 0.021). In all 3 groups, no significant change was observed in the mean CCT and CCET after contact lens wear (p > 0.05). After 6 months, the morphological changes in temporal and superior conjunctival epithelial cells were found to be significant in all groups (p < 0.001). Conclusion: Six months after SHCL wear, marked morphological changes occurred in the conjunctival epithelium. Tear function tests were also affected, while corneal thickness did not show any significant difference.