Estimation of Serum Ferritin Level to Detect Iron Deficiency Anemia in Children less than 5 Years of age (original) (raw)
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International Journal of Contemporary Pediatrics, 2019
Background: Nutritional anemia is a worldwide problem with the highest prevalence in the developing countries. One of the most vulnerable groups is 6-24 months of age. NFHS-3 survey shows that the incidence of anemia in children aged 6-35 months is 79.2% with 72.7% in urban areas and 81.2% in rural areas. First stage of iron deficiency is depletion of iron stores, which is reflected by decreased serum ferritin levels and increased total iron binding capacity (TIBC) levels. The objective of this study was to detect presence of iron deficiency in children even before clinical appearance of anemia by measuring serum ferritin levels.Methods: The study was conducted from March 2017 to November 2017 in the Department of Pediatrics of Sir Sayajirao Gaekwad General Hospital, a tertiary level hospital and government medical college, Vadodara. A cross sectional study was done in which a total of 111 asymptomatic infants and toddlers in age group of 6-24 months presenting to well-baby clinic w...
2020
Objective: To evaluate the effect of intravenous Iron therapy on serum Ferritin and Haemoglobin levels in children with iron deficiency anaemia. Study Design: Cross sectional study. Place and Duration of Study: Combined Military Hospital (CMH), Quetta, from Aug 2015 to Jul 2017. Methodology: Patients of either sex with age 1 to 12 years with iron deficiency anemia were included in the study. Sampling technique was Consecutive non-probability purposive sampling. Iron deficiency anemia was diagnosed on the basis of mean corpuscular volume (MCV), Hemoglobin (hb) concentration and serum ferritin. Intravenous iron therapy was given to all patients included in the study. Patients were followed up after 4 weeks. Paired t-test was applied for pre and post therapy HB and serum Ferritin. A p-value ≤0.05 was considered significant. Results: Total number of patients included in the study was 55. Out of total patients male were 35 (64%) and female were 20 (36%). Mean age of patients was 2.48 ± 1...
IMC Journal of Medical Science
Background and objective: Children in the developing world are vulnerable to iron deficiency (ID) and iron deficiency anemia (IDA) because they grow fast and consume diets low in iron. Thus, this study assessed anemia in children aged 6 - 12 years in rural Nigeria, using hematological indices and serum ferritin as diagnostic tools. Materials and methods: This cross-sectional study was carried out in two primary schools in Kumin Masara Kataf village in Kaduna state, Nigeria. School children aged 6 - 12 years were enrolled. Personal information and laboratory data were collected. Hemoglobin and serum ferritin concentration was estimated to determine anemia and iron status. Data analysis was done using IBM-SPSS Inc., Chicago, IL, USA, version-25.0. Results: A total of 191 school-age children aged 6 - 12 years were enrolled in the study. The overall serum ferritin was 16.51±5.20 mg/L, but the children aged 6 - 9 years had significantly (p<0.05) higher serum ferritin (17.23±5.57 mg/L)...
Serum ferritin to detect iron deficiency in children below five years of age
Paediatrica Indonesiana, 2013
Background cognitive and motor development of children until the age of is recommended and serum ferritin has been proposed as an Objective To assess the diagnostic accuracy of serum ferritin for Methods This cross-sectional, diagnostic study was conducted in for serum ferritin level use as a diagnostic tool was determined by receiver operator curve. Results Conclusions The diagnostic value of serum ferritin levels is below five years of age. [Paediatr Indones. 2013;53:150-4.].
PLOS ONE, 2016
Background Iron deficiency Anemia (IDA) in children is a recognized public health problem that impacts adversely on child morbidity, mortality and impairs cognitive development. In Pakistan information on the true prevalence and predictors of IDA is limited. This study sought to investigate IDA in children under five years of age using data from a nationally representative stratified cross-sectional survey. Methods Secondary analysis was performed on the National Nutrition Survey in Pakistan 2011-2012. We used a pre-structured instrument to collect socio demographic and nutritional data on mothers and children. We also collected Anthropometric measurements and blood samples for micronutrient deficiencies. IDA was defined as having both haemoglobin levels of <110 g/L and ferritin levels of < 12 μg/L. Data analysis was performed by applying univariate and multivariate techniques using logistic regression through SPSS.
International Journal of Contemporary Pediatrics, 2018
Background: Iron deficiency anemia is the most common nutritional deficiency disorder in the world. The present study was conducted to know the prevalence and severity of iron deficiency anemia among of 6 months to 60 months old children. A large proportion of iron deficiency is preventable with appropriate and timely intervention.Methods: This cross-sectional study was done on 100 children clinically suggestive of anemia with hemoglobin level less than 11gm/dl admitted in pediatrics ward of tertiary care hospital. 5 ml of blood sample was taken and complete hemogram, peripheral blood film and serum ferritin estimation was done. Case were studied in reference to history, age, clinical examination, hemoglobin level and confirmation of iron deficiency anemia was done by serum ferritin levels.Results: The prevalence of iron deficiency anemia in present study was 56%. It was most prevalent in the age group of 6 to 24 months. Exclusively breastfed children showed higher prevalence of iro...
Journal of Fundamental and Applied Sciences
Iron deficiency anemia (IDA) is the most common micronutrient deficiency serious health problems such as poor The main objective of the study was to investigate prevalence of IDA and its associated risk factors of school children. A cross school children (122 males and drawn for hemoglobin and serum ferritin analysis. Results revealed that the prevalence of iron deficiency without anemia was 12.6% and 7.7% of the children was found to have iron deficiency anemia. Result showed that birth weight was correlated significantly with iron deficiency based on serum ferritin concentration.
Background: Iron deficiency anemia is most common nutritional disorder in the world with higher prevalence in developing countries than developed countries. Study of the prevalence of iron deficiency anaemia will be useful if picture of the risk factors that contribute to the development of anaemia are also studied. Iron deficiency anaemia accounts for significant morbidity and mortality. There are numerous countries lacking national prevalence data in school going age group. Also, most survey data including National Family and Health Survey 4 in India, are related to the three population groups: preschool age children, pregnant women and non-pregnant women of reproductive age. Hence to determine the clinical profile and severity of iron deficiency anaemia among children aged 5-10 years, we conducted a study in a urban multispeciality hospital. Materials and Methods: Total 200 children of 5-10 years of age attending B.A.R.C. Hospital , satisfying study criteria were selected , after informed and written consent from Parents / Guardians.Detailed history regarding age, gender, contact details , socio economic status , type of diet as well as symptoms profile was taken. Complete anthropometric data (Weight , Height , Body mass index) was noted and General and Systemic examination was done. Complete blood count (CBC) of all children included in the study was done to identify children having anaemia as per WHO criteria. Serum Iron , ferritin and Total iron binding capacity (TIBC), peripheral blood smears and stool for parasite infestation was done in all anaemic children. Results: The overall prevalence of IDA was found to be 6.5 % (13/200) in children aged 5-10 years in B.A.R.C. population. There was significant association of age with occurrence of IDA (p=0.034). IDA was found to be highest i.e.16.7% among children in age group of 5-5.11 years.. Prevalence of IDA was more (11.7%) in girls than (3.3%) in boys. 76.9 % children had mild (Hb =10-11.5 g/dl) anaemia ,23.1 % children had moderate anaemia (Hb = 7-10 g/dl) and no child in our study population had severe anaemia However 12 % percent children were found to be having Iron deficiency state. Anemia was highest (66.7%) in children with Kuppuswami class III. No association was found between IDA and BMI. Occasional consumption of fruits and green leafy vegetables was associated with IDA. Conclusion: There was a low prevalence of Iron deficiency anaemia in our community. However significant number of children were having iron deficiency state. These children need close follow up to prevent development of IDA. Nutritional education of these children could prevent Iron deficiency anaemia .
Journal of Medicine, 2014
Iron deficiency is a serious health complication particularly in developing countries, which is usually caused due to poor nutrition, genetic disorders and chronic infections. Compared to developed countries prevalence of anaemia in developing and underdeveloped countries is very high, and children are the ones which are mostly affected. In this paper an attempt has been made to study the prevalence of anaemia among some school-going children in Dhaka. An attempt has also been made to assess the severity of anaemia and iron status among the school-going underprivileged children by measuring serum iron (SI), serum TIBC and serum ferritin (SF) and explore a relationship between haemoglobin level and various parameters of iron nutrition. A substantial number of indicators have been used in determining the iron deficiency.Results obtained from the study show that two thirds of the study children are anaemic due to haemoglobin level below 12 gm/dl. However, majority of them had mild anae...
Hematology, 2007
The hemoglobin (Hb), serum iron (SI), total iron binding capacity (TIBC), transferrin saturation (TS) and serum ferritin (SF) values of 240 apparently healthy children were determined in a prospective cross-sectional study conducted in Port Harcourt, Nigeria. Standard colorimetric and enzyme immunoassay procedures were used for the estimation all variables. The mean values of all parameters in this study population were; Hb (11.2 ± 1.83 gldl), TIBC (361.4 ± 245.7 ugldl, loge SI (1.807 ± 0.45), loge SF (1.51 ± 0.47) and TS (29.3 ± 18.5%). There was an age-dependent statistical significant difference in the Hb, TIBC and TS values (P < 0.01). Sex was not found to exert any significant influence on the parameters except TIBC. TS had the highest sensitivity and efficiency values of 48 and 95%, respectively. Positive predictive value (PPV), likelihood ratio (LR+) and post-test probability values were highest with SF (58%, 3.3 and 62.2%, respectively) as a diagnostic indicator. Hb values correlated positively and significantly with TS (P < 0.01), loge SI and loge SF concentrations (P < 0.05). Loge SF also correlated positively and significantly with Hb and TIBC (P < 0.05). The overall prevalence of iron deficiency anaemia among these children was 33.75%. We conclude that there is a high prevalence of iron deficiency anaemia among apparently healthy children under the age of five years in this part of the world and these results may justify the need for the introduction of a broad intervention programme for this highly vulnerable group. This study is also in support of the hypothesis that SF is the best test for diagnosing or excluding iron deficiency anaemia. The combination of SF, Hb and TS determinations may prove more useful in a resource-limited moderate setting.