Tissue Doppler echocardiography reveals distinct patterns of impaired myocardial velocities in different degrees of coronary artery disease (original) (raw)
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Echocardiography, 1997
Tissue Doppler echocardiography (TDE) is a new method by which transmural myocardial function can be studied noninvasively. I n order to investigate physiology and reproducibility, 24 young, healthy volunteers were examined by M-mode TDE. Nonuniformity of transmural tissue layer velocities became apparent: Subendocardial and subepicardial velocities of the anteroseptal myocardial wall (AW) were 3.5 2 0.7 and 1.3-c 0.5 cmlsec (P < 0.0001, t-test), whereas i n the posterolateral wall (PW) values of 3.6 +-0.6 and 1.2 0.4 cm/sec (P < 0.0001, t-test), respectively, were revealed. The ratios, termed "myocardial velocity gradients" as a new indicator of left ventricular performance, were 3.1 f 1.0 and 3.4 5 1.1, respectively. AW and PW did not differ (N.S.). Tolerance borders did not overlap, and intraobserver variability did not reach intersubject variability (P < 0.0001, F-ratio test). TDE provides new and more sophisticated insights into left ventricular performance. It seems to be accurate and reliable and therefore worth introducing into the clinical arena.
Reviews in Clinical Medicine, 2014
Coronary artery diseases affect both systolic and diastolic functions and can be assessed both globally and regionally. Tissue doppler imaging is a novel technique with additional advantages to the currently used two-dimensional echocardiography. This paper is a review of the published articles on documented Coronary artery diseases patients confirmed by angiography, without any previous myocardial infarction and with normal left ventricular ejection fraction. Accordingly, a significant relationship was achieved between systolic rather than diastolic parameters with Coronary artery diseases. Furthermore, major heterogeneity was noticed among the available studies in this respect.The incremental values of tissue doppler imaging in patients with stable angina in addition to other non invasive tests has led to its recommendation by ACC/AHA.
Journal of Clinical Medicine
Background and Aim: Dobutamine stress echocardiography (DSE) is a well-established noninvasive investigation for significant coronary artery disease (CAD). The aim of this study was to evaluate the accuracy of cardiac Doppler parameters in predicting CAD. Methods: We prospectively studied 103 consecutive patients with suspected CAD based on typical symptoms; 59 proved to have CAD, and 44 patients proved to have no-CAD (n = 44). All patients underwent a complete stress Doppler echocardiographic examination. Total isovolumic time (T-IVT) as a marker of cavity dyssynchrony and wall motion score index (WMSI) were also calculated. Results: At peak dobutamine stress, the compromised LV longitudinal excursion (MAPSE), systolic septal and lateral velocities (s’), and diastolic indices were more pronounced in the CAD patients compared with those without CAD, but LV dimension did not differ between groups (p > 0.05). The WMSI was higher and t-IVT more prolonged in patients with CAD (p <...
Journal of the American Society of Echocardiography, 2001
Because of the geometry of the basal inferior wall and its juxtaposition with the basal insertion of the posterior medial papillary muscle, accurate echocardiographic assessment of basal inferior wall motion can be challenging. Pulsed wave Doppler tissue imaging (DTI) can provide assessment of segmental myocardial motion. 1-6 We hypothesized that infarction of the basal inferior segment would decrease its DTI systolic and diastolic velocities and may enable differentiation of normal from abnormal myocardium. Because left ventricular hypertrophy (LVH) affects myocardial velocities as assessed by DTI, 7,8 and patients with myocardial infarction (MI) often have LVH, we examined the DTI velocities in 3 groups of subjects:(1) subjects with normal myocardial motion and no LVH (control subjects), (2) subjects with LVH and normal myocardial motion, and (3) subjects with recent or prior inferior MI. METHODS Subjects Inclusion criteria. We performed DTI in 99 consecutive patients who underwent 2-dimensional Doppler echocar
American Heart Journal, 1996
The velocity of myocardial contraction is an established measure of myocardial function.1 Echocardiographic quantification of regional left ventricular (LV) function has been derived previously from manually digitized M-mode tracings. 2, 3 In clinical practice, wall motion analysis consists primarily of subjective visual assessment of endocardial excursion and myocardial thickening from two-dimensional images. 4 Two independent groups have recently described novel ultrasound systems that selectively calculate and display color-coded tissue velocity from Doppler shifts created by cardiac motion on-line.5-8 Although the feasibility of these tissue Doppler imaging (TDI) systems has been demonstrated, quantitative myocardial velocity data throughout the cardiac cycle have not been described. The objectives of this study were (1) to compare TDI measures of LV wall velocity to simultaneous calculations of posterior wall velocity from digitized M-mode tracings, (2) to use color-coded TDI velocity data to quantify regional endocardial velocity of the anteroseptum and posterior wall throughout the cardiac cycle in normal subjects, and (3) to demonstrate the feasibility of color-coded velocity data to quantify alterations in regional LV function in patients with heart disease.
Echocardiography, 1999
and facilitates visual estimation of myocardial contracti1ity.l Using quantitative tissue Doppler echocardiography (QTDE), regional wall velocity can be precisely m e a~u r e d .~,~ In coronary heart disease, QTDE has been used to study the effects of drug interventions or coronary artery reva~cularization.~ As of yet, however, quantitative tissue Doppler parameters have not been validated in the clinical assessment of global systolic function in comparison with complete hemodynamic measurements. The purpose of this study was to evaluate hemodynamic determinants of systolic wall velocity indices and to demonstrate that QTDE is a feasible approach in the assessment of left ventricular systolic function. We hypothesized that tissue Doppler data are closely related to hemodynamic indices and
World Journal of Cardiovascular Diseases, 2020
Background: This study aimed to determine the impact of the percutaneous coronary intervention (PCI) on myocardial function assessed by tissue Doppler echocardiography. Methods: Conventional two-dimensional echocardiography and Myocardial tissue peak velocities were recorded at the lateral, ant.septal, post.septal, posterior, ant. and inferior angles of the mitral annulus as well as at the lateral tricuspid annulus by pulsed-wave tissue Doppler echocardiography before PCI, as well as 1 day and 6 weeks after intervention. Results: Fifty consecutive patients with chronic stable angina and preserved systolic left ventricular function (mean age, 58.3 ± 6.594 years; 32 men) undergoing PCI were studied. Conventional echocardiographic revealed no statistically significant difference between pre-and post-PCI (1 day after PCI and 6 weeks after PCI) as regarding trans-mitral and trans-tricuspid flow velocities except as regarding LVEDD, LVESD and LVEF which showed a significant improvement post-PCI. Compared with pre-interventional values, systolic peak velocity and early diastolic velocities improved at all sites (P ≤ 0.05 for each). The most pronounced improvement occurred in the septal area. Similarly, late diastolic velocities improved at all sites
Grading of Myocardial Dysfunction by Tissue Doppler Echocardiography
Journal of the American College of Cardiology, 2006
The aim of the study was to compare the ability of the tissue Doppler echocardiographic imaging (TDI) modalities velocity, strain, and displacement to quantify systolic myocardial function. BACKGROUND Several TDI modalities may be used to quantify regional myocardial function, but it is not clear how the different modalities should be applied.