Antimicrobial cathelicidin peptide LL-37 inhibits the pyroptosis of macrophages and improves the survival of polybacterial septic mice (original ) (raw )Antimicrobial Cathelicidin Peptide LL-37 Inhibits the LPS/ATP-Induced Pyroptosis of Macrophages by Dual Mechanism
Isao Nagaoka
PLoS ONE, 2014
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Therapeutic Potential of Cathelicidin Peptide LL-37, an Antimicrobial Agent, in a Murine Sepsis Model
Isao Nagaoka
International Journal of Molecular Sciences, 2020
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Therapeutic Action of Antimicrobial Cathelicidin Peptide LL-37 on a Murine Sepsis Model
Isao Nagaoka
Juntendo Medical Journal, 2020
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Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells
Isao Nagaoka
International Immunology, 2011
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An Antimicrobial Cathelicidin Peptide, Human CAP18/LL-37, Suppresses Neutrophil Apoptosis via the Activation of Formyl-Peptide Receptor-Like 1 and P2X7
Isao Nagaoka
The Journal of Immunology, 2006
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The antimicrobial peptide LL37 modulates the inflammatory and host defense response of human neutrophils
Olaf Pinkenburg
Journal of Cystic Fibrosis, 2009
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Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
Pieter Hiemstra
Cytokine, 2009
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A Novel P2X7 Receptor Activator, the Human Cathelicidin-Derived Peptide LL37, Induces IL-1 Processing and Release
Mikhail Gavrilin
The Journal of Immunology, 2004
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A Novel P2X7 Receptor Activator, the Human Cathelicidin-Derived Peptide LL37, Induces IL-1β Processing and Release1
Mikhail Gavrilin
The Journal of Immunology
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The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium
John Govan
American Journal of Respiratory Cell and Molecular Biology, 2010
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Host Defense Peptide LL-37 Selectively Reduces Proinflammatory Macrophage Responses
Kelly Brown
The Journal of Immunology, 2011
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Cathelicidin Peptide LL-37 Modulates TREM-1 Expression and Inflammatory Responses to Microbial Compounds
Pieter Hiemstra
Inflammation, 2011
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A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release
Mikhail Gavrilin
Journal of immunology (Baltimore, Md. : 1950), 2004
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Cathelicidin Peptide Sheep Myeloid Antimicrobial Peptide-29 Prevents Endotoxin-induced Mortality in Rat Models of Septic Shock
C. Silvestri
American Journal of Respiratory and Critical Care Medicine, 2004
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The antimicrobial peptide cathelicidin enhances activation of lung epithelial cells by LPS
Johannes Sierigk
The FASEB Journal, 2010
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Cathelicidin Family of Antibacterial Peptides CAP18 and CAP11 Inhibit the Expression of TNF- by Blocking the Binding of LPS to CD14 Cells1
Isao Nagaoka
2001
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The human cathelicidin LL-37 — A pore-forming antibacterial peptide and host-cell modulator
Alessandro Tossi
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2016
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Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats
Isao Nagaoka
Pediatric Surgery International, 2005
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Modulation of Neutrophil Apoptosis by Antimicrobial Peptides
Isao Nagaoka
ISRN Microbiology, 2012
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Identification of human cathelicidin peptide LL-37 as a ligand for macrophage integrin αMβ2 (Mac-1, CD11b/CD18) that promotes phagocytosis by opsonizing bacteria
Valeryi Lishko
Research and Reports in Biochemistry, 2016
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Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils
Isao Nagaoka
Innate Immunity, 2020
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The Human Antimicrobial Peptide LL-37 Is a Multifunctional Modulator of Innate Immune Responses
Michael Gold , Dawn Bowdish
The Journal of Immunology, 2002
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Human Host Defense Cathelicidin Peptide LL-37 Enhances the Lipopolysaccharide Uptake by Liver Sinusoidal Endothelial Cells without Cell Activation
Isao Nagaoka
Journal of immunology (Baltimore, Md. : 1950), 2016
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LL-37 Protects Rats against Lethal Sepsis Caused by Gram-Negative Bacteria
Barbara Skerlavaj
Antimicrobial Agents and Chemotherapy, 2006
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Cutting Edge: Cationic Antimicrobial Peptides Block the Binding of Lipopolysaccharide (LPS) to LPS Binding Protein
Wim Buurman
The Journal of Immunology, 2000
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Human cathelicidin antimicrobial peptide LL-37
Kazuhiko Okumura
2000
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Antimicrobial peptide of an anti-lipopolysaccharide factor modulates of the inflammatory response in RAW264.7 cells
Cho-fat Hui , Shih-bin Lin
Peptides, 2010
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Modulation of the TLR-Mediated Inflammatory Response by the Endogenous Human Host Defense Peptide LL-37
Kelly Brown
The Journal of Immunology, 2006
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Citrullination Alters Immunomodulatory Function of LL-37 Essential for Prevention of Endotoxin-Induced Sepsis
Krzysztof Pyrc
The Journal of Immunology, 2014
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P2X7 Receptor Regulates Internalization of Antimicrobial Peptide LL-37 by Human Macrophages That Promotes Intracellular Pathogen Clearance
Min Wan
Journal of immunology (Baltimore, Md. : 1950), 2015
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Antimicrobial cathelicidin peptide CAP11 suppresses HMGB1 release from lipopolysaccharide-stimulated mononuclear phagocytes via the prevention of necrotic cell death
Isao Nagaoka
International Journal of Molecular Medicine, 2009
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Antimicrobial peptide Cathelicidin-BF prevents intestinal barrier dysfunction in a mouse model of endotoxemia
Yizhen Wang
International immunopharmacology, 2015
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Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application
Amon Wafelman
Peptides, 2006
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In Silico Identification and Biological Evaluation of Antimicrobial Peptides Based on Human Cathelicidin LL-37
Fabrizio Carta
Antimicrobial Agents and Chemotherapy, 2006
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Augmentation of innate host defense by expression of a cathelicidin antimicrobial peptide
Daniel Weiner
Infection and immunity, 1999
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