Evaluation of a new experimental setup for radiobiology experiments at the E1 area of the ELI-NP building using FLUKA (original) (raw)

2019

Abstract

Currently there are two state-of-art research infrastructures in Romania, ELI-NP and CETAL, which use ultrahigh power lasers (10 PW in the first case, 1 PW in the second) for a wide array of research activities. One of the declared purposes of the ELI-NP project is to explore the possibility of developing new techniques in proton therapy by using laser- accelerated beams. However, it is highly probable that some of the initial experiments will be directed towards gaining more insight into the radiobiology of proton therapy and the factors that influence the relative biological effectiveness of the beam. The present paper analyses the feasibility of such radiobiology experiments at the E1 area of the ELI-NP building, using proton beams with maximum energies of up to 500 MeV. The FLUKA code is used to simulate a case in which a proton beam with 40 0 divergence is collimated on a 10-cm-diameter exit window. The beam is used to irradiate a parallelepipedal water phantom placed in air at a distance of 10 cm from the window. The phantom has a 20x20 cm 2 cross area and a depth of 10 cm. We present the results regarding beam homogeneity and symmetry at the phantom entrance side, as well as the depth dose curves and the depth LET curves, both for primary protons and for all ionizing particles. We conclude by showing how this information can be used for designing the setup of radiobiology experiments at an ultrahigh power laser area.

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