Highlights From the Institute for Functional Medicine's 2014 Annual Conference: Functional Perspectives on Food and Nutrition: The Ultimate Upstream Medicine (original) (raw)
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Journal of the American Dietetic Association, 2008
The Institute of Medicine recently convened a workshop to review the state of the various domains of nutritional genomics research and policy and to provide guidance for further development and translation of this knowledge into nutrition practice and policy. Nutritional genomics holds the promise to revolutionize both clinical and public health nutrition practice and facilitate the establishment of (a) genome-informed nutrient and food-based dietary guidelines for disease prevention and healthful aging, (b) individualized medical nutrition therapy for disease management, and (c) better targeted public health nutrition interventions (including micronutrient fortification and supplementation) that maximize benefit and minimize adverse outcomes within genetically diverse human populations. As the field of nutritional genomics matures, which will include filling fundamental gaps in knowledge of nutrient-genome interactions in health and disease and demonstrating the potential benefits of customizing nutrition prescriptions based on genetics, registered dietitians will be faced with the opportunity of making genetically driven dietary recommendations aimed at improving human health.
Dietary Epigenetics: Are You What Your Parents Ate?
Epigenetics in Society, 2015
A book about the emerging field of epigenetics and its societal implications written in a simple, yet exciting, manner. Written by students of diverse disciplines, and reviewed by experts in the field, it is intended for students and educated lay people. We hope this accessible book will excite further interest and concern regarding the social, ethical, legal, health, and policy implications that the field of will have for all arenas of our lives.
Nutriepigenomics Advances into Personalized Nutrition
BJSTR, 2017
This review presents an omics systems perspective that presents an integrated approach to understanding the contribution of the genetic, epigenetic, metabolomic, and proteomic interactions under the influence of a dynamic nutritional environment. The review takes into account the application of genomic and post-genomic era methodologies being used to study the impact of inter-individual phenotypic differences and disease susceptibility to current and future generations. Every individual alive today is a combination of the heliotypes inherited from their parents, and the results of genetic-epigenetic interaction influencing the fetal epigenome during pre-natal development and post-natal life. Epigenetic marks imprinted in-utero are attributed to deficits in the maternal contribution to the fetal nutritional environment. Integral to this discussion is the concept of developmental plasticity, which presents itself as an unfolding narrative in the “developmental origins of health and disease” (DOHaD) hypothesis, and the ‘predictive adaptive response (PAR)’ concept. When taken together, these concepts present the case for an adaptive response to developmental programming that canpredispose an individual to future diseaseor confers an advantage. Nutriepgenomics is the study of how nutrients affect human health through epigenetic modifications. Recent advances investigating how the nutritional environment during embryonic development influences the establishment of metabolic phenotypes that can contribute to the emergence of disease are discussed. Several encouraging trials suggest that prevention and therapy of age- and lifestyle-related diseases by individualized tailoring to optimal epigenetic diets including combinations of natural products, polyphenols or drugs are conceivable
Nutrigenetics and Nutrigenomic Is Changing the Field of Nutrition
Home Health Care Management & Practice, 2015
Over the past several decades new dietary approaches were advertised as the greatest new panacea for maintaining health and fitness. Lay diet books were flying off the shelves as many delved deep into the text learning the science behind the trendsetting diet, wading through various recipes in an effort to witness transformational results from healthy eating. The therapeutic approach to nutritional health was based on the assumption that all individuals have similar nutritional requirements with the minor exceptions of gender, age, height, weight, and level of physical activity. It is obvious that individuals in similar situations who follow the same dietary recommendations frequently experience different outcomes. The one-size-fits-all approach to helping individuals adopt healthy eating habits eventually fails for a large majority because of the principles of nutrigenetics and nutrigenomics. Imagine the possibilities for larger changes in individuals utilizing these principles to affect their short-and long-term health through a personalized dietary plan. Although this personalized dietary approach is not yet ready for prime time, it is clearly changing the face of nutrition and future nutritional approaches for health benefits.
Nutrients
Background: Nutrigenetics indicates that individual genetic variability results in altered health outcomes necessitating personalized nutrition adaptation. Registered dietitians are recognized as the clinical nutrition experts, but their knowledge and attitudes regarding nutrigenetics has not been delineated. Methods: This cross sectional online survey was conducted in a convenience sample of 169 national nutrition conference attendees. The survey queried demographics, knowledge, and attitudes towards nutrigenetics and information on training in nutrigenetics. Results: The majority of participants were registered dietitians and female, 45% of whom held advanced degrees. Personalized nutrition was perceived by 93.5% of participants as highly important or important; however, 94% of respondents indicated they are not sufficiently knowledgeable in personalized nutrition and only 9.5% had received training in nutrigenetics. The mean nutrigenetics knowledge score was 6.89 ± 1.67 (out of a...